Patents by Inventor Neelima Sinha

Neelima Sinha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-(4-arylpiperazin-1-yl)-&ohgr;-[N-(&agr;&ohgr;-dicarboximido)]-alkanes useful as uro-selective &agr;1-adrenoceptor blockers
    Patent number: 6420366
    Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective &agr;1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: July 16, 2002
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Nitya Anand, Neelima Sinha, Sanjay Jain, Anita Mehta, Jang Bahadur Gupta
  • 1-(4-arylpiperazin-1-yl)-&ohgr;-[N-(&agr;,&ohgr;-dicarboximido)]-alkanes useful as uro-selective &agr;1-adrenoceptor blockers
    Patent number: 6420559
    Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective &agr;1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: July 16, 2002
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Nitya Anand, Neelima Sinha, Sanjay Jain, Anita Mehta, Anil Kumar Saxena
  • 1-(4-arylpiperazin-1-y1)-&ohgr;-[N-(&agr;,&ohgr;-dicarboximido)]-alkanes useful as uro-selective &agr;1-adrenoceptor blockers
    Patent number: 6410735
    Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective &agr;1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: June 25, 2002
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Nitya Anand, Neelima Sinha, Sanjay Jain, Anita Mehta, Anil Kumar Saxena
  • 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes and their use in medical treatments
    Patent number: 6150367
    Abstract: A chemical compound and composition of Formula 1: ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; said compounds and compositions as being useful therapeutic agents for hypertension, ischemic, cardiovascular and other adrenergic receptor related disorders.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: November 21, 2000
    Assignee: Council of Scientific & Industrial Research
    Inventors: Neelima Sinha, Sanjay Jain, Anil Kumar Saxena, Nitya Anand, Ram Mohan Saxena, Mangal Prasad Dubey, Madhur Ray, Gyanendra K. Patnaik, deceased
  • 1-(4-arylpiperazin-1-yl)-.omega.-[n-(.alpha... omega.-dicarboximido)]-alkanes useful as uro-selective .alpha..sub.1 -adrenoceptor blockers
    Patent number: 6090809
    Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective .alpha..sub.1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: July 18, 2000
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Nitya Anand, Neelima Sinha, Sanjay Jain, Anita Mehta, Anil Kumar Saxena
  • 1-(4-arylpiperazin-1-yl)-.omega.-[n-(.alpha.,.omega.-dicarboximido)]-alka nes useful as uro-selective .alpha.1-adrenoceptor blockers
    Patent number: 6083950
    Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective .alpha..sub.1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
    Type: Grant
    Filed: July 21, 1998
    Date of Patent: July 4, 2000
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Nitya Anand, Neelima Sinha, Sanjay Jain, Anita Mehta, Jang Bahadurgupta
  • Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes
    Patent number: 6084097
    Abstract: The invention relates to a process for the synthesis of 1-[4-Arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes used as potential therapeutic agents for hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders, having general formula 1 ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; a process of preparing said compounds and a method of treating hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders.
    Type: Grant
    Filed: October 29, 1997
    Date of Patent: July 4, 2000
    Assignee: Council of Scientific & Industrial Research
    Inventors: Neelima Sinha, Sanjay Jain, Anil Kumar Saxena, Nitya Anand, Ram Mohan Saxena, Mangal Prasad Dubey, Madhur Ray, Gyanendra Kumar Patnaik, deceased