Abstract: System and method configured to operate under conditions when the object being imaged destroys or negates the information which otherwise allows the user to take advantage of optical parallax, configured to elicit luminescence from the same targets in the object as a result of irradiation of these targets with pump light at different, respectively corresponding wavelengths, and acquire optical data from so-illuminated targets through the very same optical path to image the object at different wavelengths. One embodiment enables acquisition, by the same optical detector and from the same object, of imaging data that includes a reflectance image and multiple fluorescence-based images caused by light at different wavelengths, to assess difference in depths of locations of targets within the object.

Abstract: An imaging probe can include a photoluminescent carbon nanostructure configured to emit a wavelength of light detectable through living tissue, and a targeting moiety including a first binding partner configured to interact with a second binding partner.

Abstract: Systems and methods are provided to obtain optical coherence tomography data and fluorescence imaging data from an object. The systems and methods use a single light source to illuminate and excite fluorescence in the object and a common optical path including an optical fiber to provide illumination and excitation light and collect reflected and emitted light at the object. The optical coherence tomography data and fluorescence imaging data can be combined to produce morphological images of an object with additional location-specific fluorescence cues.

Abstract: A method, and corresponding system, can include identifying a plurality of wavelength spectral band components in hyperspectral image data, the spectral band components corresponding to mutually distinct sources of image contrast. An intensity image corresponding to each respective spectral band component can be calculated, followed by combining the respective intensity images to form an inter-band image based on the respective, mutually distinct sources of image contrast for each spectral band component. Intensity images can be hyperspectral or hyperdiffuse images. Hyperdiffuse imaging can be performed for each spectral band component identified using hyperspectral measurements. Spectral position and spectral width images corresponding to each spectral band component can be calculated and used to determine depth of features inside a surface of the target. Diffuse width images can be calculated from hyperdiffuse image data and used to determine depth.

Abstract: System and method configured to operate under conditions when the object being imaged destroys or negates the information which otherwise allows the user to take advantage of optical parallax, configured to elicit luminescence from the same targets in the object as a result of irradiation of these targets with pump light at different, respectively corresponding wavelengths, and acquire optical data from so-illuminated targets through the very same optical path to image the object at different wavelengths. One embodiment enables acquisition, by the same optical detector and from the same object, of imaging data that includes a reflectance image and multiple fluorescence-based images caused by light at different wavelengths, to assess difference in depths of locations of targets within the object.

Abstract: Embodiments described herein generally relate to compositions comprising a graphene oxide species. In some embodiments, the compositions advantageously have relatively high oxygen content, even after annealing.

Abstract: Embodiments described herein generally relate to compositions comprising a graphene oxide species. In some embodiments, the compositions advantageously have relatively high oxygen content, even after annealing.