Abstract: A method and apparatus model multiple relationship dimensions among a set of entities is presented. A computer system identifies a configuration for the structure. The configuration comprises metadata about supported relationship aspects for the set of entities within a structure context. The computer system identifies aspects for an entity according to the structure context. The entity aspects comprise metadata about relationships for the entity within the structure context. The computer system compares the entity aspects to the configuration for the structure to determine a relationship of the entity to the set of entities. The computer system dynamically attaches the entity to the set of entities according to the determined relationship to form the structure.

Abstract: A method and apparatus model multiple relationship dimensions among a set of entities is presented. A computer system identifies a configuration for the structure. The configuration comprises metadata about supported relationship aspects for the set of entities within a structure context. The computer system identifies aspects for an entity according to the structure context. The entity aspects comprise metadata about relationships for the entity within the structure context. The computer system compares the entity aspects to the configuration for the structure to determine a relationship of the entity to the set of entities. The computer system dynamically attaches the entity to the set of entities according to the determined relationship to form the structure.

Abstract: The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acids. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing ?, ?-dialkylated amino acids in a site-specific manner. Specifically, the invention relates to the synthesis of VIP peptide derivatives, which bind selectively to VIP receptors on target cells. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.

Abstract: The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acids. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing &agr;, &agr;-dialkylated amino acids in a site-specific manner. Specifically, the invention relates to the synthesis of VIP peptide derivatives, which bind selectively to VIP receptors on target cells. The invention encompasses methods for the generation of these peptides, compositions containing the peptides and the pharmacological applications of these peptides especially in the treatment and prevention of cancer.

Abstract: The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acids. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing &agr;,&agr;-dialkylated amino acids in a site-specific manner. Specifically, the invention relates to the synthesis of VIP peptide derivatives, which bind selectively to VIP receptors on target cells.