Abstract: A mechanical circulatory support system may include a blood pump, a housing, an elongate shaft, a first sheath, and a second sheath. The blood pump may be configured to pump blood from a ventricle of a heart of a patient to vasculature of the patient. The elongate shaft may be coupled with the blood pump and extend proximally from the blood pump to the housing. The first sheath may extend over the elongate shaft distal of the housing and include a lumen with an inner diameter. The second sheath may extend over the elongate shaft distal of the housing and include an outer diameter that is less than the inner diameter of the lumen of the first sheath. The first sheath and the second sheath are configured to longitudinally adjust over the elongate shaft and an entirety of the second sheath is configured to adjust through the first sheath.

Abstract: A mechanical circulatory support system may include a blood pump, a housing, an elongate shaft, a first sheath, and a second sheath. The blood pump may pump blood from a ventricle of a heart of a patient to vasculature of the patient. The elongate shaft may couple with the blood pump and extend proximally from the blood pump to the housing. The first sheath may have a first hub and a lumen with an inner diameter. The second sheath may have a second hub and an outer diameter that is less than the inner diameter of the lumen. The first sheath and the second sheath may longitudinally advance over the elongate shaft and a distal end of the second sheath may advance through the lumen and extend distally beyond a distal end of the first sheath.

Abstract: An introducer sheath including a valve hub and an elongate shaft extending from the valve hub. The valve hub defines a main port and a side port. The main port includes a hub body, a compressible seal disposed within the hub body, a pusher at least partially positioned within the hub body and slidably movable relative thereto, and a lock nut partially surrounding the pusher. The lock nut is threadably engaged with the pusher such that rotation of the lock nut moves the pusher axially toward and/or away from the compressible seal.

Abstract: A guide catheter is adapted for providing improved backup support while accessing an ostium of a patient's left coronary artery. The guide catheter includes an elongate shaft having a proximal shaft portion and a power zone shaft portion. The elongate shaft includes an inner polymeric layer extending through the proximal shaft portion and the power zone shaft portion, and outer polymeric layer, and a braid that is disposed between the inner polymeric layer and the outer polymeric layer and extends through the proximal shaft portion and the power zone shaft portion, the braid having a first PIC count within the power zone shaft portion and a second PIC count within the proximal shaft portion. The elongate shaft is biased into a primary curve disposed distal of the power zone shaft portion and a coplanar secondary curve disposed within the power zone shaft portion.

Abstract: An introducer sheath including a valve hub and an elongate shaft extending from the valve hub. The valve hub defines a main port and a side port. The main port includes a hub body, a compressible seal disposed within the hub body, a pusher at least partially positioned within the hub body and slidably movable relative thereto, and a lock nut surrounding the pusher. The lock nut is threadably engaged with the hub body such that rotation of the lock nut moves the pusher axially toward and/or away from the compressible seal.

Abstract: An introducer sheath including a valve hub and an elongate shaft extending from the valve hub. The valve hub defines a main port and a side port. The main port includes a hub body, a seal disposed within the hub body, a main port lid attached to the hub body, a tightening port hub attached to the main port lid, a compressible seal disposed within a lumen of the tightening port hub, a pusher at least partially positioned within the lumen of the tightening port hub and slidably movable relative thereto, and a lock nut surrounding the pusher. The lock nut is threadably engaged with the tightening port hub such that rotation of the lock nut moves the pusher axially toward and/or away from the compressible seal.

Abstract: An example apparatus includes: memory having a terminal, the memory to store machine-readable instructions and adjacent channel leakage data; and programmable circuitry having a terminal coupled to the terminal of the memory, the programmable circuitry to execute the machine-readable instructions to: determine a range of out-of-band frequencies responsive to adjacent channel leakage ratio data; generate weight values responsive to electromagnetic emissions within the range of out-of-band frequencies of a first signal; modify a pre-distortion function responsive to the weight values; and apply the modified pre-distortion function to generate a second signal, the second signal to exhibit fewer emissions in the range of out-of-band frequencies than the first signal during transmission.

Abstract: A sheath for receiving a medical device includes a hub and a body portion. The body portion is configured to be disposed in a patient. An access conduit is coupled to the hub. A stopcock is coupled to the access conduit opposite the hub. The stopcock includes a first leg coupled to the access conduit, a second leg having a male luer connector, and a third leg having a female luer connector.

Abstract: A valve hub assembly for use with a sheath includes a valve hub with a proximal end opposite a distal end, a first arm defining a lumen, and a second arm defining a lumen. A tightening port is arranged at the proximal end of the valve hub. The tightening port includes a hub cap engaged with the tightening port, a radially expandable seal positioned in a lumen of the hub cap, a pusher engaged with the radially expandable seal and at least partially disposed within the hub cap, and a lock nut arranged around the pusher and configured for pressing of the pusher against the radially expandable seal.

Abstract: An attachment device for coupling with a hub includes a base having a proximal end, a distal end, and a lumen extending along a longitudinal axis between the proximal end and the distal end, a first extension coupled with the base, the first extension having a leg portion and a base portion, the base portion comprising at least one opening and a second extension coupled with the base, the second extension having a leg portion and a base portion, the base portion comprising at least one opening. The attachment device includes wherein the leg portion of the first extension and the leg portion of the second portion are each angled relative to the longitudinal axis of the base and wherein the base is composed of an elastomeric material such that the attachment device provides strain relief at both the proximal end and the distal end.

Abstract: A variety of medical procedures utilize two or more medical device components, including medical device components where a first medical device component is advanced within a second medical component. An example would be an elongate dilator used in combination with a guide catheter. The guide catheter and the elongate dilator may be adapted to provide a rotational lock mechanism that allows the guide catheter and the elongate dilator to lock together such that rotating one of the components causes rotation of both components. In some instances, the guide catheter and the elongate dilator may cooperate to also provide a relative axial lock between the two components.

Abstract: A tightening port for use with a hub of an introducer sheath includes a cartridge for reversible engagement with a proximal end of the hub, the cartridge having a proximal end and a distal end and a lumen extending therebetween, a seal positioned within the lumen of the cartridge, a lock nut having an inner portion positioned within the lumen of the cartridge and an outer portion configured for engagement with the proximal end of the cartridge, such that the inner portion of the lock nut is configured to push the seal to reduce a size of an opening of the seal.

Abstract: A tightening port for use with a hemostasis valve of an introducer sheath includes a gripper configured for engagement with the hemostasis valve hub, the gripper having a proximal end, a distal end, a cylindrical body defining a lumen, and a plurality of protrusions extending from the proximal end, a base having a cylindrical body and a lumen defined therethrough for receiving a portion of the gripper, and a plurality of engagement features configured for engaging with the plurality of protrusions of the gripper, and wherein the lumen of the gripper has an initial diameter prior to engagement with the base, and the lumen of the gripper has a compressed diameter after engagement with the base, wherein the compressed diameter is less than the initial diameter.

Abstract: A hemostasis valve hub for a sheath, such as an introducer sheath, includes a hub base including a first arm defining a first lumen and having a distal end and a proximal end and a second arm extending from the first arm and defining a second lumen and having a distal end and a proximal end, a seal positioned within the first lumen and adjacent a lock nut, the lock nut engaged with the proximal end of the first arm and positioned at least partially within the first lumen, a primary seal positioned adjacent the proximal end of the first arm, and a secondary seal positioned adjacent the proximal end of the second arm.

Abstract: A hemostasis valve hub for use with an introducer sheath includes a base having a securing mechanism for securing the hemostasis valve hub to the introducer sheath, an outer shell securable to the base and defining an interior volume, a shutter helix section disposed within the interior volume and including a plurality of fins arranged in a helical fashion, a brush section disposed within the interior volume adjacent the disk shutter section, the brush section including a plurality of brushes arranged in a helical fashion, and a seal positioned within the base and adjacent the brush section, the seal having a partial cross slit arrangement.

Abstract: A hemostasis valve hub for an introducer sheath includes a hub base, a hub cap configured for engagement with the hub base, the hub cap having a first wall with a first opening and a second opening extending through the first wall, a manifold positioned within the hub cap and adjacent the hub base, a primary seal positioned adjacent the first opening of the hub cap, a secondary seal positioned adjacent the second opening of the hub cap, and wherein the primary seal and the secondary seal are configured to provide a fluid seal between the first opening and the second opening, respectively, and the hub base.

Abstract: A virtual content store may be provided. Upon receiving a request for a content stream from a subscriber at a regional headend, a central content vault may be examined to determine whether the content stream is available. Once the content stream is determined to be available in the central content vault, a streaming session may be established to the subscriber from the regional headend. The content stream may be retrieved from the central content vault and provided to the subscriber via the streaming session.

Abstract: A virtual content store may be provided. Upon receiving a request for a content stream from a subscriber at a regional headend, a central content vault may be examined to determine whether the content stream is available. Once the content stream is determined to be available in the central content vault, a streaming session may be established to the subscriber from the regional headend. The content stream may be retrieved from the central content vault and provided to the subscriber via the streaming session.