Abstract: A method for maintaining a measure of accumulated energy delivered to an appliance includes a supervisor repeatedly receiving from a first smart socket a measure of energy delivered to the appliance by the first smart socket and maintaining a measure of accumulated energy delivered to the appliance. When the first smart socket fails and is replaced, the method includes repeatedly receiving from the second smart socket a measure of energy delivered to the appliance by the second smart socket, maintaining the measure of accumulated energy delivered to the appliance based at least in part on the measures previously received from the first smart socket and the measures repeatedly received from the second smart socket of energy delivered to the appliance by the second smart socket, and displaying the measure of accumulated energy delivered to the appliance on a dashboard.

Abstract: For each discovered smart socket, the smart socket is automatically added to a supervisor database and a predetermined set of two or more objects for the smart socket are automatically added to the supervisor database. One or more predetermined alarm extensions are automatically added to predetermined ones of the two or more objects of the smart socket in the supervisor database. One or more predetermined history extensions are automatically added to predetermined ones of the two or more objects of the smart socket in the supervisor database. Predetermined ones of the two or more objects and/or extensions of each of the discovered smart sockets are automatically mapped to a predetermined dashboard.

Abstract: Energy consumption may be reduced by tracking a measure of baseline energy over time in order to determine which of the one or more appliances have a power on mode and a power standby mode based at least in part on the measure of baseline energy delivered to each of the appliances during the baseline time period, wherein the power standby mode consumes less power than the power on mode. During subsequent operation, the supervisor identifies when an appliance is in a power standby mode, and turns off the socket receptacles of the smart sockets that corresponds to those appliances identified as being in their power standby mode.

Abstract: A cooking system includes a housing defining a hollow chamber configured to receive food. The housing has an upper portion defining an opening to said hollow chamber. A lid is movable relative to the housing between an open position and a closed position. The lid seals the opening to the hollow chamber when in the closed position. A portion of the lid is selectively positionable to form a pressure-tight heating volume between the hollow chamber and the portion of said lid. At least one heating element is associated with at least one of the housing and the lid. The at least one heating element is arranged within the pressure-tight heating volume.

Abstract: A virtual object system can coordinate interactions between multiple virtual objects in an artificial reality environment. Embodiments receive a first virtual object, the first virtual object including first properties, where the artificial reality environment is set in a real-world environment. Embodiments register the first properties of the first virtual object to receive notifications of events from the artificial reality environment. Embodiments receive one or more queries from a second virtual object and in response to the one or more queries, respond to the second virtual object with identified features of the real-world environment in which the artificial reality environment is set and identifications of one or more other virtual objects (e.g., the first virtual object). The second virtual object can use the identification of the first virtual object to register for events related to the first virtual object and/or communicate with the first virtual object.

Abstract: Provided herein is a diamond gammavoltaic cell comprising: a diamond body having a diamond body surface including first and second opposing surfaces; a low-barrier electrical contact formed on the first surface; and a high-barrier electrical contact formed on the second surface, wherein the diamond body surface that is not in contact with either the low-barrier electrical contact or the high-barrier electrical contact is at least partially surface transfer doped to provide a p-type surface.

Abstract: There is provided a connector, for introducing or extracting a material to or from at least one receptacle, comprising a housing extending between a distal end and a proximal end, the housing comprising, at least at one end, a pierceable seal; a hollow needle mounted, at least partially, within the housing between the distal end and the proximal end of the housing, a first end of the hollow needle being connected or connectable to a first corresponding receptacle, and a second end of the hollow needle facing the pierceable seal at an end of the housing; and an actuating mechanism acting on the housing or the hollow needle to enable the hollow needle to pierce the pierceable seal thereby forming a communication through the pierceable seal, such that material is able to transfer through the connector.

Abstract: There is provided a connector, for introducing or extracting a material to or from at least one receptacle, comprising a housing extending between a distal end and a proximal end, the housing comprising, at least at one end, a pierceable seal; a hollow needle mounted, at least partially, within the housing between the distal end and the proximal end of the housing, a first end of the hollow needle being connected or connectable to a first corresponding receptacle, and a second end of the hollow needle facing the pierceable seal at an end of the housing; and an actuating mechanism acting on the housing or the hollow needle to enable the hollow needle to pierce the pierceable seal thereby forming a communication through the pierceable seal, such that material is able to transfer through the connector.

Abstract: Provided are ex vivo systems and methods of predicting the response of a drug or other agent on a tissue. In some embodiments, the systems and methods comprise cutting a tissue into tissue fragments, adding a drug or other agent to the tissue fragments based on an estimated tumor content, and performing an ex vivo measurement on the tissue fragments.

Abstract: The present disclosure relates to a bidirectional communication circuit for bidirectional communication between a first differential wired network and a second differential wired network and a related method of operating the bidirectional communication circuit. In particular, the present disclosure relates to a bidirectional communication circuit designed to prevent timing glitches and simultaneous transmission of data from the first network to the second network and from the second network to the first network.

Abstract: Mooring systems and methods are provided. One system may include at least one object partially or fully submerged in a body of water. The system may also include a semi-rigid outer ring that is adrift or moored to at least one sea anchor or to the sea floor by at least one mooring line. At least one object may be connected or tethered by bridle lines to the semi-rigid outer ring to form an array.

Abstract: A compound which is an arylimidazolyl isoxazole of formula (I): (Formula (I)) or a pharmaceutically acceptable salt thereof. The compound has activity in modulating the activity of p300 and/or CBP and is used to treat cancer, particularly prostate cancer.

Abstract: Provided are ex vivo systems and methods of predicting the response of a drug or other agent on a tissue. In some embodiments, the systems and methods comprise cutting a tissue into tissue fragments, adding a drug or other agent to the tissue fragments based on an estimated tumor content, and performing an ex vivo measurement on the tissue fragments.

Abstract: Provided are ex vivo systems and methods of predicting the response of a drug or other agent on a tissue. In some embodiments, the systems and methods comprise cutting a tissue into tissue fragments, adding a drug or other agent to the tissue fragments based on an estimated tumor content, and performing an ex vivo measurement on the tissue fragments.

Abstract: The present disclosure relates to a bidirectional communication circuit for bidirectional communication between a first differential wired network and a second differential wired network and a related method of operating the bidirectional communication circuit. In particular, the present disclosure relates to a bidirectional communication circuit designed to prevent timing glitches and simultaneous transmission of data from the first network to the second network and from the second network to the first network.

Abstract: A methodology and system, devices and computing apparatus are presented for personalizing ride hailing services. A proprietary social media platform is integrated with a computing apparatus providing ride hailing services. The proprietary social media platform allows users and drivers to selectively share comments, posts and ratings that are used to personalize rides and increase the quality of taxi-like services while minimizing risks and helping drivers better monetize the taxi-like services.

Abstract: There is provided a connector, for introducing or extracting a material to or from at least one receptacle, comprising a housing extending between a distal end and a proximal end, the housing comprising, at least at one end, a pierceable seal; a hollow needle mounted, at least partially, within the housing between the distal end and the proximal end of the housing, a first end of the hollow needle being connected or connectable to a first corresponding receptacle, and a second end of the hollow needle facing the pierceable seal at an end of the housing; and an actuating mechanism acting on the housing or the hollow needle to enable the hollow needle to pierce the pierceable seal thereby forming a communication through the pierceable seal, such that material is able to transfer through the connector.

Abstract: A cartridge assembly (2, 200) for use in an aerosol-generating system comprises: a cartridge (4) having an upstream end and a downstream end, the cartridge (4) comprising: at least one compartment (12, 14) having an air inlet at the upstream end of the cartridge (4) and an air outlet downstream of the air inlet; a removable first seal (20) secured to the upstream end of the cartridge (4), wherein the removable first seal (20) obstructs the air inlet of the at least one compartment (12, 14) and is configured to be removed by a user prior to use of the cartridge assembly (2); and a cartridge actuation portion (18) on an inner surface of a downstream end portion of the cartridge (4).

Abstract: Mooring systems and methods are provided. One system may include at least one object partially or fully submerged in a body of water. The system may also include a semi-rigid outer ring that is adrift or moored to at least one sea anchor or to the sea floor by at least one mooring line. At least one object may be connected or tethered by bridle lines to the semi-rigid outer ring to form an array.

Abstract: A compound which is an arylimidazolyl isoxazole of formula (I): (Formula (I)) or a pharmaceutically acceptable salt thereof. The compound has activity in modulating the activity of p300 and/or CBP and is used to treat cancer, particularly prostate cancer.