Patents by Inventor Neil Barnwell

Neil Barnwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production Processes of S- and O-Diacylated Gamma-Glutamyl-Cysteamine Prodrugs
    Publication number: 20220106267
    Abstract: Methods are provided for the synthesis of a compound of formula (X). R2 is selected from —H, —C1-C4-alkyl, —C2-C4-alkenyl and C1-C4-aryl; R3 is selected from —C(O)H and —C(O)C1-C4-alkyl; and A is a pharmaceutically acceptable anion (e.g. a halide). Also provided are intermediate compounds formed during the synthesis.
    Type: Application
    Filed: February 14, 2020
    Publication date: April 7, 2022
    Inventors: Rosaleen Joy Anderson, Lisa Frost, Neil Barnwell, Matthew Levick, Ivan Hales, Michael Dunn
  • Process
    Publication number: 20160002261
    Abstract: Processes for the preparation of the compound of formula II and intermediate compounds for use in the processes.
    Type: Application
    Filed: September 17, 2015
    Publication date: January 7, 2016
    Inventors: Neil Barnwell, Philip Cornwall, Duncan Michael Gill, Gareth P. Howell, Rebecca Elizabeth Meadows, Eric Merifield, Christopher William Mitchell, Andiappan Murugan, Philip O Keefe, Zakariya Mohamed Patel, James Barry Rose, John Singleton, Jane Withnall
  • PROCESS
    Publication number: 20140364601
    Abstract: Processes for the preparation of the compound of formula (II) and intermediate compounds for use in the processes.
    Type: Application
    Filed: May 11, 2012
    Publication date: December 11, 2014
    Applicant: ASTRAZENECA AB
    Inventors: Neil Barnwell, Philip Cornwall, Duncan Michael Gill, Gareth P. Howell, Rebecca Elizabeth Meadows, Andiappan Murugan, Philip O'Keefe, John Singleton, Jane Withnall, Eric Merifield, Christopher William Mitchell, Zakariya Mohamed Patel, James Barry Rose
  • Novel Crystal Modifications
    Publication number: 20090221640
    Abstract: Novel crystal modifications of (5S)-5-[4-(5-chloro-pyridin-2-yloxy)-piperidine-1-sulfonylmethyl]-5-methyl-imidazolidine-2,4-dione are disclosed together with processes for preparing such modifications, pharmaceutical compositions comprising such a modification, and the use of such a modification in therapy.
    Type: Application
    Filed: March 15, 2007
    Publication date: September 3, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Lars-Erik Briggner, Anders Eriksson, Neil Barnwell, Andrea Cole, Jacob Perkins, Luis-Manuel Vaz, Andrew Wells
  • 3,7-Diazabicyclo [3.3.1] formulations as anti-arrhythmic compounds
    Patent number: 7217708
    Abstract: There is provided substantially crystalline forms of 4-({3-[7-(3,3-dimethyl-2-oxobutyl) -9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]propyl}amino)benzo-nitrile; tert-butyl 2 -{7-[3-(4-cyanoanilino)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylcarbamate; tert-butyl 2-{7-[4-(4-cyanophenyl)butyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethylcarbamate; or tert-butyl 2-{7-[2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylcarbamate and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of cardiac arhythmias.
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: May 15, 2007
    Assignee: Astrazeneca AB
    Inventors: Neil Barnwell, Annika Björe, Lal Cheema, David Cladingboel, Adam Herring, Karin Lövqvist
  • 3,7-diazabicyclo [3.3.1] formulations as antiarhythmic compounds
    Publication number: 20040143000
    Abstract: There is provided substantially crystalline forms of 4-({3-[7-(3,3-dimethyl-2-oxobutyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]propyl}amino)benzo-nitrile; 2-{7-[3-(4-cyanoanilino)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylcarbamate; tert-butyl 2-{7-[4-(4-cyanophenyl)butyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethylcarbamate; or tert-butyl 2-{7-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylcarbamate and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of cardiac arrhythmias.
    Type: Application
    Filed: October 10, 2003
    Publication date: July 22, 2004
    Inventors: Neil Barnwell, Annika Bjre, Lal Cheema, David Cladingboel, Adam Herring, Karin Lvqvist