Patents by Inventor Neil C. Leatherbury
Neil C. Leatherbury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7524335Abstract: A fiber-reinforced, polymeric implant material useful for tissue engineering, and method of making same are provided. The fibers are preferably aligned predominantly parallel to each other, but may also be aligned in a single plane. The implant material comprises a polymeric matrix, preferably a biodegradable matrix, having fibers substantially uniformly distributed therein. Inorganic particles may also be included in the implant material. In preferred embodiments, porous tissue scaffolds are provided which facilitate regeneration of load-bearing tissues such as articular cartilage and bone. Non-porous fiber-reinforced implant materials are also provided herein useful as permanent implants for load-bearing sites.Type: GrantFiled: August 31, 2004Date of Patent: April 28, 2009Assignee: Smith & Nephew, Inc.Inventors: Michael A. Slivka, Gabriele G. Niederauer, Kristine Kieswetter, Neil C. Leatherbury
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Publication number: 20040193154Abstract: A method and device for inserting an implant of synthetic material or healthy bone or cartilage into a bone or cartilage defect of unknown depth. The device includes an inner shaft within a hollow outer shaft. One end of the inner shaft of the device is suitable for inserting into the bone or cartilage defect in order to determine the depth, while the other end of the outer shaft is suitable for holding an implant. The implant is cut to fit the defect once its depth has been determined and then inserted into the defect. A cutting device for cutting the implant is disclosed. Also disclosed is an implant capsule loader for inserting an implant into the delivery device.Type: ApplicationFiled: February 23, 2004Publication date: September 30, 2004Applicant: OsteoBiologics, Inc.Inventors: Neil C. Leatherbury, Mark Q. Niederauer, Fred B. Dinger, Joe D. Blandford
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Patent number: 6783712Abstract: A fiber-reinforced, polymeric implant material useful for tissue engineering, and method of making same are provided. The fibers are preferably aligned predominantly parallel to each other, but may also be aligned in a single plane. The implant material comprises a polymeric matrix, preferably a biodegradable matrix, having fibers substantially uniformly distributed therein. In preferred embodiments, porous tissue scaffolds are provided which facilitate regeneration of load-bearing tissues such as articular cartilage and bone. Non-porous fiber-reinforced implant materials are also provided herein useful as permanent implants for load-bearing sites.Type: GrantFiled: November 4, 2002Date of Patent: August 31, 2004Assignee: Osteobiologics, Inc.Inventors: Michael Slivka, Gabriele G. Niederauer, Kristine Kieswetter, Neil C. Leatherbury
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Publication number: 20030114937Abstract: This invention provides biodegradable, biocompatible polymeric films having uniform selected thicknesses between about 60 micrometers and about 5 mm useful in the manufacture of therapeutic implants for insertion into a patient's body and methods of making them. The films may be shaped to cover implants made of other materials to improve their biocompatibility. The films may be coated with or incorporate bioactive agents. They may have differing properties, e.g., porosity, thickness, and degradation rate, in different areas.Type: ApplicationFiled: January 28, 2003Publication date: June 19, 2003Inventors: Neil C. Leatherbury, Kristine Kieswetter, Michael A. Slivka, Gabriele Niederauer
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Publication number: 20030075822Abstract: A fiber-reinforced, polymeric implant material useful for tissue engineering, and method of making same are provided. The fibers are preferably aligned predominantly parallel to each other, but may also be aligned in a single plane. The implant material comprises a polymeric matrix, preferably a biodegradable matrix, having fibers substantially uniformly distributed therein. In preferred embodiments, porous tissue scaffolds are provided which facilitate regeneration of load-bearing tissues such as articular cartilage and bone. Non-porous fiber-reinforced implant materials are also provided herein useful as permanent implants for load-bearing sites.Type: ApplicationFiled: November 4, 2002Publication date: April 24, 2003Inventors: Michael Slivka, Gabriele G. Niederauer, Kristine Kieswetter, Neil C. Leatherbury
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Patent number: 6514286Abstract: This invention provides biodegradable, biocompatible polymeric films having uniform selected thicknesses between about 60 micrometers and about 5 mm useful in the manufacture of therapeutic implants for insertion into a patient's body. The films may be shaped to cover implants made of other materials to improve their biocompatibility. The films may be coated with or incorporate bioactive agents. They may have differing properties, e.g., porosity, thickness, and degradation rate, in different areas.Type: GrantFiled: May 5, 1999Date of Patent: February 4, 2003Assignee: Osteobiologics, Inc.Inventors: Neil C. Leatherbury, Kristine Kieswetter, Michael A. Slivka, Gabriele Niederauer
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Patent number: 6511511Abstract: A fiber-reinforced, polymeric implant material useful for tissue engineering, and method of making same are provided. The fibers are preferably aligned predominantly parallel to each other, but may also be aligned in a single plane. The implant material comprises a polymeric matrix, preferably a biodegradable matrix, having fibers substantially uniformly distributed therein. In preferred embodiments, porous tissue scaffolds are provided which facilitate regeneration of load-bearing tissues such as articular cartilage and bone. Non-porous fiber-reinforced implant materials are also provided herein useful as permanent implants for load-bearing sites.Type: GrantFiled: October 25, 1999Date of Patent: January 28, 2003Assignee: OsteoBiologics, Inc.Inventors: Michael Slivka, Gabriele G. Niederauer, Kristine Kieswetter, Neil C. Leatherbury
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Patent number: 6344496Abstract: Biodegradable polymeric therapeutic substantially nonporous implant materials incorporating bioactive ceramics such as Bioglass® ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.Type: GrantFiled: October 5, 1999Date of Patent: February 5, 2002Assignees: OsteoBiologics, Inc., USBiomaterials CorporationInventors: Gabriele Niederauer, Kristine Kieswetter, Neil C. Leatherbury, David C. Greenspan
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Publication number: 20010051833Abstract: This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. Particulate implant materials are provided, especially useful as autologous bone graft materials.Type: ApplicationFiled: March 19, 2001Publication date: December 13, 2001Inventors: Mary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer
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Patent number: 6203573Abstract: This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.Type: GrantFiled: January 21, 1999Date of Patent: March 20, 2001Assignee: OsteoBiologics, Inc.Inventors: Mary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer
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Patent number: 6156068Abstract: This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.Type: GrantFiled: January 21, 1999Date of Patent: December 5, 2000Assignee: OsteoBiologics, Inc.Inventors: Mary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer
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Patent number: 5977204Abstract: Biodegradable polymeric therapeutic implant materials incorporating bioactive ceramics such as Bioglass.RTM. ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.Type: GrantFiled: April 11, 1997Date of Patent: November 2, 1999Assignees: OsteoBiologics, Inc., USBiomaterials CorporationInventors: Barbara D. Boyan, Gabriele Niederauer, Kristine Kieswetter, Neil C. Leatherbury, David C. Greenspan
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Patent number: 5863297Abstract: This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.Type: GrantFiled: October 8, 1996Date of Patent: January 26, 1999Assignee: OsteoBiologics, Inc.Inventors: Mary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer
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Patent number: 5716413Abstract: This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.Type: GrantFiled: October 11, 1995Date of Patent: February 10, 1998Assignee: OsteoBiologics, Inc.Inventors: Mary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer