Patents by Inventor Neil C. Sheppard

Neil C. Sheppard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAR-T CONSTRUCTS COMPRISING A NOVEL CD19 BINDER COMBINED WITH IL18 AND METHODS OF USING THE SAME
    Publication number: 20240131068
    Abstract: The disclosure relates to immune cells comprising one or more vectors comprising a nucleic acid sequence encoding a chimeric antigen receptor specific for CD19 and a nucleic acid sequence encoding an enhancer of T cell priming (e.g., IL-18), compositions comprising the T cells, and methods of generating and/or using the T cells to treat diseases associated with the expression of CD19.
    Type: Application
    Filed: October 17, 2023
    Publication date: April 25, 2024
    Applicants: Kite Pharma, Inc., The Trustees of the University of Pennsylvania
    Inventors: Neil C. Sheppard, Yanping Luo, David Barrett, Regina Young
  • CD19 BINDERS, CAR-T CONSTRUCTS COMPRISING THE SAME, AND METHODS OF USING THE SAME
    Publication number: 20240123068
    Abstract: The disclosure relates to chimeric antigen receptor (CAR) specific to CD19, vectors encoding the same, and recombinant T cells comprising the CD19 CAR. The disclosure also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD19 binding domain.
    Type: Application
    Filed: October 18, 2023
    Publication date: April 18, 2024
    Applicants: Kite Pharma, Inc., The Trustees of the University of Pennsylvania
    Inventors: Neil C. Sheppard, Yanping Luo, David Barrett, Regina Young