Patents by Inventor Neil COOCH

Neil COOCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANCER VACCINES TARGETING LEMD1 AND USES THEREOF
    Publication number: 20220265800
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen are disclosed. Methods of treating a subject with a LEMD1-expressing tumor and methods of preventing a LEMD1-expressing tumor are disclosed. Mutated consensus LEMD1 antigen is disclosed.
    Type: Application
    Filed: April 25, 2022
    Publication date: August 25, 2022
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • Cancer Vaccines Targeting PRAME and Uses Thereof
    Publication number: 20220265801
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen are disclosed. Methods of treating a subject with a PRAME-expressing tumor and methods of preventing a PRAME-expressing tumor are disclosed. Mutated consensus PRAME antigen is disclosed.
    Type: Application
    Filed: April 25, 2022
    Publication date: August 25, 2022
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • Cancer vaccines targeting LEMD1 and uses thereof
    Patent number: 11338028
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen are disclosed. Methods of treating a subject with a LEMD1-expressing tumor and methods of preventing a LEMD1-expressing tumor are disclosed. Mutated consensus LEMD1 antigen is disclosed.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: May 24, 2022
    Assignee: Inovio Pharmaceuticals, Inc.
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • Cancer vaccines targeting PRAME and uses thereof
    Patent number: 11338029
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen are disclosed. Methods of treating a subject with a PRAME-expressing tumor and methods of preventing a PRAME-expressing tumor are disclosed. Mutated consensus PRAME antigen is disclosed.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: May 24, 2022
    Assignee: Inovio Pharmaceuticals, Inc.
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • CANCER VACCINES TARGETING MUC16 AND USES THEREOF
    Publication number: 20220111026
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen are disclosed. Methods of treating a subject with a MUC16-expressing tumor and methods of preventing a MUC16-expressing tumor are disclosed. Modified consensus MUC16 antigen is disclosed.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • Cancer vaccines targeting MUC16 and uses thereof
    Patent number: 11235044
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen are disclosed. Methods of treating a subject with a MUC16-expressing tumor and methods of preventing a MUC16-expressing tumor are disclosed. Modified consensus MUC16 antigen is disclosed.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: February 1, 2022
    Assignee: Inovio Pharmaceuticals, Inc.
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • CANCER VACCINES TARGETING BORIS AND USES THEREOF
    Publication number: 20210401958
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen are disclosed. Methods of treating a subject with a BORIS-expressing tumor and methods of preventing a BORIS-expressing tumor are disclosed. A synthetic consensus BORIS antigen is disclosed.
    Type: Application
    Filed: September 20, 2021
    Publication date: December 30, 2021
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • CANCER VACCINES TARGETING MESOTHELIN AND USES THEREOF
    Publication number: 20210401959
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen are disclosed. Methods of treating a subject with a mesothelin-expressing tumor and methods of preventing a mesothelin-expressing tumor are disclosed. Modified consensus mesothelin antigen is disclosed.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 30, 2021
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • Cancer vaccines targeting mesothelin and uses thereof
    Patent number: 11154602
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen are disclosed. Methods of treating a subject with a mesothelin-expressing tumor and methods of preventing a mesothelin-expressing tumor are disclosed. Modified consensus mesothelin antigen is disclosed.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: October 26, 2021
    Assignee: Inovio Pharmaceuticals, Inc.
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • Cancer vaccines targeting BORIS and uses thereof
    Patent number: 11154601
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen are disclosed. Methods of treating a subject with a BORIS-expressing tumor and methods of preventing a BORIS-expressing tumor are disclosed. A synthetic consensus BORIS antigen is disclosed.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: October 26, 2021
    Assignee: Inovio Pharmaceuticals, Inc.
    Inventors: Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
  • OPTIMIZED NUCLEIC ACID ANTIBODY CONSTRUCTS
    Publication number: 20210188947
    Abstract: Disclosed herein are compositions comprising structurally modified DNA encoded antibodies (DMAbs), methods of structurally modifying DMAbs, and methods of using structurally modified DMAbs.
    Type: Application
    Filed: May 10, 2018
    Publication date: June 24, 2021
    Inventors: David Weiner, Ghiabe Guibinga, Neil Cooch, Charles Reed
  • CANCER VACCINES TARGETING LEMD1 AND USES THEREOF
    Publication number: 20190175712
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen are disclosed. Methods of treating a subject with a LEMD1-expressing tumor and methods of preventing a LEMD1-expressing tumor are disclosed. Mutated consensus LEMD1 antigen is disclosed.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 13, 2019
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • CANCER VACCINES TARGETING PRAME AND USES THEREOF
    Publication number: 20190175713
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen are disclosed. Methods of treating a subject with a PRAME-expressing tumor and methods of preventing a PRAME-expressing tumor are disclosed. Mutated consensus PRAME antigen is disclosed.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 13, 2019
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • CANCER VACCINES TARGETING MUC16 AND USES THEREOF
    Publication number: 20190175708
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen are disclosed. Methods of treating a subject with a MUC16-expressing tumor and methods of preventing a MUC16-expressing tumor are disclosed. Modified consensus MUC16 antigen is disclosed.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 13, 2019
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • CANCER VACCINES TARGETING SURVIVIN AND USES THEREOF
    Publication number: 20190175707
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode synthetic consensus Survivin antigens. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode synthetic consensus Survivin antigens are disclosed. Methods of treating a subject with a Survivin-expressing tumor and methods of preventing a Survivin-expressing tumor are disclosed. Synthetic consensus Survivin antigens are disclosed.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 13, 2019
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • CANCER VACCINES TARGETING MESOTHELIN AND USES THEREOF
    Publication number: 20190175711
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen are disclosed. Methods of treating a subject with a mesothelin-expressing tumor and methods of preventing a mesothelin-expressing tumor are disclosed. Modified consensus mesothelin antigen is disclosed.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 13, 2019
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
  • CANCER VACCINES TARGETING BORIS AND USES THEREOF
    Publication number: 20190175710
    Abstract: Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen are disclosed. Methods of treating a subject with a BORIS-expressing tumor and methods of preventing a BORIS-expressing tumor are disclosed. A synthetic consensus BORIS antigen is disclosed.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 13, 2019
    Inventors: Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH