Patents by Inventor Neil D. Perkins

Neil D. Perkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagents and methods for identifying and modulating expression of genes regulated by CDK inhibitors
    Publication number: 20030186424
    Abstract: This invention provides methods and reagents for identifying compounds that inhibit the induction of genes involved in cancer, age-related diseases, and viral diseases, such genes being induced by p21Waf1/Cip1/Sdi1.
    Type: Application
    Filed: August 29, 2002
    Publication date: October 2, 2003
    Inventors: Igor B. Roninson, Neil D. Perkins, David J. Gregory, Jason C. Poole
  • DNA and RNA encoding proteins useful in the regulation of KB-containing genes, and cells containing same
    Patent number: 5460965
    Abstract: Proteins, and corresponding DNA and RNA sequences, useful for the regulation of expression of .kappa.B-containing genes are disclosed. These proteins are useful to either stimulate or inhibit the expression of .kappa.B-containing genes. Proteins stimulating the expression of .kappa.B-containing genes have an amino acid sequence at least 80% identical to the amino acid sequence of from position 1 to position 374 of p100 [SEQ ID NO: 2]. Proteins having an inhibitory effect on the expression of .kappa.B-containing genes have sequences either at least 80% identical to the amino acid sequence of from position 407 to the carboxyl end of p100 [SEQ ID NO: 2] or having an amino acid sequence at least 80% identical to the amino sequence of either from position 1 to 100 sor from position 101 to position 374 of p100 [SEQ ID NO: 2].
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: October 24, 1995
    Assignee: The Regents of the University of Michigan
    Inventors: Gary J. Nabel, Roland M. Schmid, Neil D. Perkins
  • Proteins useful in the regulation of .kappa.B-containing genes
    Patent number: 5324818
    Abstract: Proteins, and corresponding DNA and RNA sequences, useful for the regulation of expression of .kappa.B-containing genes are disclosed. These proteins are useful to either stimulate or inhibit the expression of .kappa.B-containing genes. Proteins stimulating the expression of .kappa.B-containing genes have an amino acid sequence at least 80% identical to the amino acid sequence of from position 1 to position 374 of p100 [SEQ ID NO: 2]. Proteins having an inhibitory effect on the expression of .kappa.B-containing genes have sequences either at least 80% identical to the amino acid sequence of from position 407 to the carboxyl end of p100 [SEQ ID NO: 2] or having an amino acid sequence at least 80% identical to the amino sequence of either from position 1 to 100 sor from position 101 to position 374 of p100 [SEQ ID NO: 2].
    Type: Grant
    Filed: August 21, 1991
    Date of Patent: June 28, 1994
    Assignee: The Regents of the University of Michigan
    Inventors: Gary J. Nabel, Roland M. Schmid, Neil D. Perkins
  • Proteins useful in the regulation of .kappa.B-containing genes
    Patent number: RE35823
    Abstract: Proteins, and corresponding DNA and RNA sequences, useful for the regulation of expression of .kappa.B-containing genes are disclosed. These proteins are useful to either stimulate or inhibit the expression of .kappa.B-containing genes. Proteins stimulating the expression of .kappa.B-containing genes have an amino acid sequence at least 80% identical to the amino acid sequence of from position 1 to position 374 of p100 ?SEQ ID NO: 2!. Proteins having an inhibitory effect on the expression of .kappa.B-containing genes have sequences either at least 80% identical to the amino acid sequence of from position 407 to the carboxyl end of p100 ?SEQ ID NO: 2! or having an amino acid sequence at least 80% identical to the amino sequence of either from position 1 to 100 sor from position 101 to position 374 of p100 ?SEQ ID NO: 2!.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: June 9, 1998
    Assignee: The Regents of the University of Michigan
    Inventors: Gary J. Nabel, Roland M. Schmid, Neil D. Perkins