Patents by Inventor Neil David Pearson

Neil David Pearson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity
    Patent number: 6962917
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: November 8, 2005
    Assignee: SmithKline Beecham P.L.C.
    Inventors: David Thomas Davies, Graham Elgin Jones, Andrew P Lightfoot, Roger Edward Markwell, Neil David Pearson
  • Quinoline derivatives as antibacterials
    Patent number: 6911442
    Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or N-oxide thereof: corresponding novel medicaments, pharmaceutical compositions and/or methods of
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: June 28, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Thomas Davies, Roger Edward Markwell, Neil David Pearson, Andrew Kenneth Takle
  • Compounds and methods for the treatment of neoplastic disease
    Patent number: 6803369
    Abstract: A method of modulating the activity of a aberrant cell topoisomerase enzyme involving contacting the enzyme with a compound that inhibits enzyme-mediated cleavage of a polynucleotide substrate with which the enzyme is in complex. Pharmaceutical compositions containing such compounds may be used to treat neoplasias or to inhibit the growth of certain cancer cells. Screening methods can be employed to identify other compounds for these uses.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: October 12, 2004
    Assignees: SmithKline Beecham Corporation, SmithKlineBeecham p.l.c.
    Inventors: Symon G. Erskine, Michael Gwynn, Neil David Pearson, Edwina Imogen Wilding
  • Medicaments
    Publication number: 20040198756
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: May 24, 2004
    Publication date: October 7, 2004
    Inventors: David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials
    Publication number: 20040198755
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: May 24, 2004
    Publication date: October 7, 2004
    Inventors: Catherine Genevieve Yvette Dartois, Roger Edward Markwell, Guy Marguerite Marie Gerard Nadler, Neil David Pearson
  • Nitrogen-containing bicyclic heterocycles for use as antibacterials
    Publication number: 20040171620
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: April 6, 2004
    Publication date: September 2, 2004
    Inventors: Gerald Brooks, David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Quinolines and nitrogenated derivative therof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents
    Publication number: 20040138219
    Abstract: Piperidine derivatives of formula (I) and pharmaceutically derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: January 26, 2004
    Publication date: July 15, 2004
    Inventors: David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, William Miller, Neil David Pearson
  • Compounds
    Publication number: 20040116452
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: November 24, 2003
    Publication date: June 17, 2004
    Applicant: SmithKline Beecham p.I.c.
    Inventors: Roger Edward Markwell, Neil David Pearson
  • Quinolines and nitrogenated derivatives thereof substituted in 4-position by a piperazine-containing moiety and their use as antibacterial agents
    Publication number: 20040077656
    Abstract: Piperazine derivatives, containing a quinoline analog moiety, of formula (I) and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammal, particularly in man.
    Type: Application
    Filed: November 13, 2003
    Publication date: April 22, 2004
    Inventors: Roger Edward Markwell, Neil David Pearson, Christian Smethurst
  • Piperazine derivatives for treatment of bacterial infections
    Publication number: 20040077655
    Abstract: Piperazine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: November 13, 2003
    Publication date: April 22, 2004
    Inventors: Catherine Genevieve Yvette Dartois, Roger Edward Markwell, Marcel Moran, Guy Marguerite Marie Gerard, Neil David Pearson
  • Quinoline derivatives as antibacterials
    Publication number: 20040053928
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 18, 2004
    Inventors: David Thomas Davies, Roger Edward Markwell, Neil David Pearson
  • Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity
    Publication number: 20040038998
    Abstract: Aminopiperidine derivatives of formula (I) and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: August 28, 2003
    Publication date: February 26, 2004
    Inventors: David Thomas Davies, Graham Elgin Jones, Andrew Peightfoot, Roger Edward Markwell, Neil David Pearson
  • Naphthrydine compounds and their azaisosteric analogues as antibacterials
    Publication number: 20030212084
    Abstract: Piperidine derivatives of formula (I) or a pharmaceutically acceptable derivative thereof and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: December 20, 2001
    Publication date: November 13, 2003
    Inventors: Ian Keith Hatton, Neil David Pearson
  • Compounds and methods for the treatment of neoplastic disease
    Publication number: 20030203917
    Abstract: A method of modulating the activity of a aberrant cell topoisomerase enzyme involving contacting the enzyme with a compound that inhibits enzyme-mediated cleavage of a polynucleotide substrate with which the enzyme is in complex. Pharmaceutical compositions containing such compounds may be used to treat neoplasias or to inhibit the growth of certain cancer cells. Screening methods can be employed to identify other compounds for these uses.
    Type: Application
    Filed: May 20, 2003
    Publication date: October 30, 2003
    Applicant: SmithKline Beecham Corporation and SmithKline Beecham p.l.c.
    Inventors: Symon G. Erskine, Michael Gwynn, Neil David Pearson, Edwina Imogen Wilding
  • Quinoline derivatives and their use as antibacterial agents
    Patent number: 6602882
    Abstract: Piperidine derivatives and pharmaceutical derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: August 5, 2003
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Thomas Davies, Roger Edward Markwell, Neil David Pearson, Andrew Kenneth Takle
  • METHOD FOR SCREENING COMPOUNDS WHICH INTERACT WITH THE L-ENANTIOMER OF A TARGET RNA
    Publication number: 20010007743
    Abstract: A method of identifying compounds which interact, directly or indirectly, with a target molecule of interest, wherein the target molecule of interest is an RNA, comprises screening compounds for interaction with the (L)-enantiomer of the said RNA, and identifying, as hits, the enantiomers of those compounds for which a said interaction is detected.
    Type: Application
    Filed: May 26, 1999
    Publication date: July 12, 2001
    Inventors: DAVID JUSTIN CHARLES KNOWLES, BRIAN METCALF, NEVILLE HUBERT NICHOLSON, NEIL DAVID PEARSON, CATHERINE DENISE PRESCOTT