Patents by Inventor Neil E. Kay

Neil E. Kay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASSESSING AND TREATING CANCER
    Publication number: 20250269022
    Abstract: This document provides methods and materials for assessing cancer. For example, methods and materials that can be used to determine if a mammal (e.g., a human) having cancer is likely to be responsive to a cancer immunotherapy (e.g., a chimeric T cell therapy) are provided. In some cases, methods and materials for treating a mammal having cancer and identified as being likely to respond to a cancer immunotherapy (e.g., a chimeric T cell therapy) are also provided.
    Type: Application
    Filed: May 6, 2022
    Publication date: August 28, 2025
    Inventors: Saad J. Kenderian, Michelle J. Cox, Neil E. Kay
  • Methods and materials for treating cancer
    Patent number: 12257286
    Abstract: This document relates to methods and materials involved in treating mammals having a cancer (e.g., a cancer having one or more CD19 positive extracellular vesicles (EVs) and/or one or more small EVs in the tumor microenvironment). For example, methods of treating a mammal having a blood cancer including one or more CD19 positive EVs and/or one or more small EVs in the blood by administering one or more cancer immunotherapies (e.g., one or more chimeric antigen receptor (CAR) T-cell therapies) to the mammal are provided.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: March 25, 2025
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Saad J. Kenderian, Neil E. Kay, Michelle J. Cox, Fabrice Lucien-Matteoni
  • METHODS AND MATERIALS FOR TREATING CANCER
    Publication number: 20210401886
    Abstract: This document relates to methods and materials involved in treating mammals having a cancer (e.g., a cancer having one or more CD19 positive extracellular vesicles (EVs) and/or one or more small EVs in the tumor microenvironment). For example, methods of treating a mammal having a blood cancer including one or more CD19 positive EVs and/or one or more small EVs in the blood by administering one or more cancer immunotherapies (e.g., one or more chimeric antigen receptor (CAR) T-cell therapies) to the mammal are provided.
    Type: Application
    Filed: October 31, 2019
    Publication date: December 30, 2021
    Inventors: Saad J. Kenderian, Neil E. Kay, Michelle J. Cox, Fabrice Lucien-Matteoni
  • MATERIALS AND METHODS FOR TREATING CANCER
    Publication number: 20210145830
    Abstract: This document provides methods for determining biological age of mammalian subjects or assessing whether the subjects are aging normally. Also provided herein are methods for determining whether therapeutic treatment or other interventions for reversing or slowing down aging are effective. This document also provides methods and materials for slowing the progression of biological aging.
    Type: Application
    Filed: April 5, 2019
    Publication date: May 20, 2021
    Inventors: Saad J. Kenderian, Neil E. Kay, Reona Sakemura, Steven L. Warner, David J. Bearss, Jason Marc Foulks, Lars Mouritsen, Clifford J. Whatcott
  • METHODS OF TREATING HEMATOLOGIC CANCERS
    Publication number: 20140274937
    Abstract: This disclosure relates to the treatment of hematologic cancers, for example, cancers of the blood, by methods that include administration of EGCG and at least one of a purine nucleoside analog and an alkylating agent. In particular, methods of treating chronic lymphocytic leukemia (CLL) and acute lymphocytic leukemia (ALL) are described.
    Type: Application
    Filed: May 30, 2014
    Publication date: September 18, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Neil E. Kay, Tait D. Shanafelt
  • Methods of treating hematologic cancers
    Patent number: 8772264
    Abstract: This disclosure relates to the treatment of hematologic cancers, for example, cancers of the blood, by methods that include administration of EGCG and at least one of a purine nucleoside analog and an alkylating agent. In particular, methods of treating chronic lymphocytic leukemia (CLL) and acute lymphocytic leukemia (ALL) are described.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: July 8, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Neil E. Kay, Tait D. Shanafelt
  • METHODS OF TREATING HEMATOLOGIC CANCERS
    Publication number: 20120190638
    Abstract: This disclosure relates to the treatment of hematologic cancers, for example, cancers of the blood, by methods that include administration of EGCG and at least one of a purine nucleoside analog and an alkylating agent. In particular, methods of treating chronic lymphocytic leukemia (CLL) and acute lymphocytic leukemia (ALL) are described.
    Type: Application
    Filed: July 27, 2010
    Publication date: July 26, 2012
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Neil E. Kay, Tait D. Shanafelt