Patents by Inventor Neil Fanger
Neil Fanger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190070287Abstract: The present disclosure is directed to compositions comprising one or more components of a polypeptide, a reovirus-derived targeting protein, and a cleavable linker, and related methods and compositions for the generation of tolerance against the polypeptide. In some embodiments, the polypeptide is antigenic, such as comprising at least one epitope from a food allergen, an environmental allergen, an auto-antigen, and/or a biological therapeutic, and/or at least one epitope derived therefrom.Type: ApplicationFiled: February 10, 2017Publication date: March 7, 2019Applicant: Virtici, LLCInventors: Neil A. Fanger, Paul Hill, Stacy Martin
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Publication number: 20180243408Abstract: The present disclosure is directed to compositions comprising one or more components of a polypeptide allergen combined with a reovirus-derived targeting protein, and related methods for the generation of tolerance against the polypeptide allergens.Type: ApplicationFiled: February 12, 2016Publication date: August 30, 2018Applicant: Virtici, LLCInventors: Neil A. Fanger, Paul Hill
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Patent number: 7935338Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: GrantFiled: December 11, 2002Date of Patent: May 3, 2011Assignees: University of Massachusetts, Corixa CorporationInventors: Gary R. Fanger, Neil Fanger, David King, Marc W. Retter, Kenneth L. Rock
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Publication number: 20100303817Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: ApplicationFiled: December 8, 2009Publication date: December 2, 2010Applicants: UNIVERSITY OF MASSACHUSETTS, Corixa CorporationInventors: Gary R. FANGER, Neil FANGER, David KING, Marc W. RETTER, Kenneth L. ROCK
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Patent number: 7781569Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: GrantFiled: April 28, 2006Date of Patent: August 24, 2010Assignees: University of Massachusetts, Corixa CorporationInventors: Gary Fanger, Neil Fanger, David John King, Marc W. Retter, Kenneth L. Rock
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Publication number: 20070031423Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: ApplicationFiled: April 28, 2006Publication date: February 8, 2007Applicants: UNIVERSITY OF MASSACHUSETTS, Corixa CorpInventors: Gary Fanger, Neil Fanger, David King, Marc Retter, Kenneth Rock
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Publication number: 20060275307Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: ApplicationFiled: August 1, 2006Publication date: December 7, 2006Applicants: UNIVERSITY OF MASSACHUSETTS, Corixa CorpInventors: Gary Fanger, Neil Fanger, David King, Marc Retter, Kenneth Rock
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Publication number: 20060263374Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: ApplicationFiled: August 1, 2006Publication date: November 23, 2006Applicants: UNIVERSITY OF MASSACHUSETTS, Corixa CorpInventors: Gary Fanger, Neil Fanger, David King, Marc Retter, Kenneth Rock
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Patent number: 7049063Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.Type: GrantFiled: December 12, 2000Date of Patent: May 23, 2006Assignee: Corixa CorporationInventors: Tongtong Wang, Liqun Fan, Michael D. Kalos, Chaitanya S. Bangur, Nancy A. Hosken, Gary R. Fanger, Samuel X. Li, Aijun Wang, Yasir A. W. Skeiky, Robert A. Henderson, Patricia D. McNeill, Neil Fanger
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Patent number: 7010760Abstract: An autofill algorithm provides tools for defining and automatically executing batch based procedures in an adaptive hierarchical workflow environment, and may be suitable for a large variety of applications including laboratory procedure planning, execution, documentation, as wells ad driving robotic apparatus.Type: GrantFiled: March 11, 2004Date of Patent: March 7, 2006Assignee: Teranode CorporationInventors: Lawrence F. Arnstein, Zheng Li, John M. Hill, Michael R. Kellen, Christophe Poulain, Neil A. Fanger, Kuang Chen
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Publication number: 20050065767Abstract: A method for integrating models of biological systems (i.e., molecules, cells, organs, organisms) that can be simulated with models of laboratory procedures that can be executed, to support close-loop iteration between in silico and physical modeling and experimentation in support of scientific research, discovery, and product development.Type: ApplicationFiled: August 3, 2004Publication date: March 24, 2005Applicant: Teranode CorporationInventors: Lawrence Arnstein, Neil Fanger, Michael Kellen, Zheng Li
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Publication number: 20040243599Abstract: An autofill algorithm provides tools for defining and automatically executing batch based procedures in an adaptive hierarchical workflow environment, and may be suitable for a large variety of applications including laboratory procedure planning, execution, documentation, as wells ad driving robotic apparatus.Type: ApplicationFiled: March 11, 2004Publication date: December 2, 2004Applicant: Teranode CorporationInventors: Lawrence F. Arnstein, Zheng Li, John M. Hill, Michael R. Kellen, Christophe Poulain, Neil A. Fanger, Kuang Chen
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Publication number: 20040126378Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: ApplicationFiled: December 11, 2002Publication date: July 1, 2004Inventors: Gary R. Fanger, Neil Fanger, David King, Marc W. Retter, Kenneth L. Rock
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Publication number: 20040115204Abstract: Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.Type: ApplicationFiled: December 11, 2002Publication date: June 17, 2004Inventors: Gary R. Fanger, Neil Fanger, David King, Marc W. Retter, Kenneth L. Rock
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Publication number: 20030064947Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.Type: ApplicationFiled: November 30, 2001Publication date: April 3, 2003Applicant: Corixa CorporationInventors: Tongtong Wang, Aijun Wang, Yasir A. W. Skeiky, Samuel X. Li, Michael D. Kalos, Robert A. Henderson, Patricia D. McNeill, Neil Fanger, Marc W. Retter, Margarita Durham, Gary R. Fanger, Thomas S. Vedvick, Darrick Carter, Yoshihiro Watanabe, David W. Peckham, Feng Cai, Teresa M. Foy
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Publication number: 20020147143Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.Type: ApplicationFiled: June 28, 2001Publication date: October 10, 2002Applicant: Corixa CorporationInventors: Tongtong Wang, Margarita Durham, Gary R. Fanger, Thomas S. Vedvick, Darrick Carter, Yoshihiro Watanabe, Robert A. Henderson, David W. Peckham, Neil Fanger
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Publication number: 20020052329Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.Type: ApplicationFiled: December 12, 2000Publication date: May 2, 2002Inventors: Tongtong Wang, Liqun Fan, Michael D. Kalos, Chaitanya S. Bangur, Nancy A. Hosken, Gary R. Fanger, Samuel X. Li, Aijun Wang, Yasir A. W. Skeiky, Robert A. Henderson, Patricia D. McNeill, Neil Fanger