Patents by Inventor Neil Howard

Neil Howard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020087011
    Abstract: Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentano[b]pyridine derivatives. The most preferred compounds prepared by this inventino are (+)(1S,2R,3S)-3-[2-(2-hydroxyeth-1-yloxy)-4-methoxyphenyl]-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof and (+)(1S,2R,3S)-3-[(2-carboxymethoxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof. Also invented are novel intermediates useful in preparing these compounds.
    Type: Application
    Filed: September 10, 2001
    Publication date: July 4, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Yemane Woldeselassie Andemichael, Neil Howard Baine, William Morrow Clark, Conrad John Kowalski, Michael Anthony McGuire, Robert John Mills
  • Patent number: 6408587
    Abstract: A structural member, e.g. a truss for erection of temporary structures, comprises a number of elongate elements disposed in spaced generally parallel relationship to one another with transversely extending elements therebetween, and an element extending longitudinally of the structural member has a formation extending lengthwise of it for engagement by an attachment member which is to be retained to the longitudinally extending element at any of a range of positions therealong. The attachment member may provide for connection of a safety element to the structural member, and be freely movable therealong in use.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: June 25, 2002
    Assignee: Total Fabrications Limited
    Inventors: Christopher Patrick Noel Cronin, Neil Howard Darracott
  • Publication number: 20010044455
    Abstract: A method of treatment using a compound of Formula I: 1
    Type: Application
    Filed: May 23, 2001
    Publication date: November 22, 2001
    Applicant: Boehringer Mannheim Pharmaceuticals Corporation-
    Inventors: Mary Ann Lukas-Laskey, Robert Ruffolo, Neil Howard Shusterman, Gisbert Sponer, Klaus Strein
  • Patent number: 6288247
    Abstract: Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentano[b]pyridine derivatives. The most preferred compounds prepared by this invention are (+)(1S, 2R, 3S)-3-[2-(2-hydroxyeth-1-yloxy)-4-methoxyphenyl]-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof and (+)(1S, 2R, 3S)-3-(2-carboxymethoxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof. Also invented are novel intermediates useful in preparing these compounds.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: September 11, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Yemane Woldeselassie Andemichael, Neil Howard Baine, William Morrow Clark, Conrad John Kowalski, Michael Anthony McGuire, Robert John Mills
  • Publication number: 20010004823
    Abstract: A structural member, e.g. a truss for erection of temporary structures, comprises a number of elongate elements disposed in spaced generally parallel relationship to one another with transversely extending elements therebetween, and an element extending longitudinally of the structural member has a formation extending lengthwise of it for engagement by an attachment member which is to be retained to the longitudinally extending element at any of a range of positions therealong. The attachment member may provide for connection of a safety element to the structural member, and be freely movable therealong in use.
    Type: Application
    Filed: December 21, 2000
    Publication date: June 28, 2001
    Inventors: Christopher Patrick Noel Cronin, Neil Howard Darracott
  • Patent number: 6147232
    Abstract: Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentano[b]pyridine derivatives. The most preferred compounds prepared by this invention are (+)(1S, 2R, 3S)-3-[2-(2-hydroxyeth-1-yloxy)-4-methoxyphenyl]-1-(3,4-methylenedioxyphen yl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof and (+)(1S, 2R, 3S)-3-(2-carboxymethoxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(p rop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof. Also invented are novel intermediates useful in preparing these compounds.
    Type: Grant
    Filed: May 8, 1998
    Date of Patent: November 14, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Yemane Woldeselassie Andemichael, Neil Howard Baine, William Morrow Clark, Conrad John Kowalski, Michael Anthony McGuire, Robert John Mills
  • Patent number: 5859266
    Abstract: Polymorph "A" a novel polymorphic form of N-t-butyl-androst-3,5-diene-17.beta.-carboxamide-3-carboxylic acid. Novel processes for preparing polymorph "A" are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 12, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Neil Howard Baine, Neville Lewis Holder, Donald Nathaniel Klein, Robert Lee Webb, Gary Edward Zuber
  • Patent number: 5760069
    Abstract: A method of treatment using a compound of Formula I: ##STR1## wherein: R.sub.1 is hydrogen, lower alkanoyl of up to 6 carbon atoms or aroyl selected from benzoyl and naphthoyl;R.sub.2 is hydrogen, lower alkyl of up to 6 carbon atoms or arylalkyl selected from benzyl, phenylethyl and phenylpropyl;R.sub.3 is hydrogen or lower alkyl of up to 6 carbon atoms;R.sub.4 is hydrogen or lower alkyl of up to 6 carbon atoms, or when X is oxygen, R.sub.4 together with R.sub.5 can represent --CH.sub.2 --O--;X is a valency bond, --CH.sub.2, oxygen or sulfur;Ar is selected from phenyl, naphthyl, indanyl and tetrahydronaphthyl;R.sub.5 and R.sub.6 are individually selected from hydrogen, fluorine, chlorine, bromine, hydroxyl, lower alkyl of up to 6 carbon atoms, a --CONH.sub.2 -- group, lower alkoxy of up to 6 carbon atoms, benzyloxy, lower alkylthio of up to 6 carbon atoms, lower alkysulphinyl of up to 6 carbon atoms and lower alkylsulphonyl of up to 6 carbon atoms; orR.sub.5 and R.sub.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 2, 1998
    Assignee: Boehringer Mannheim Pharmaceuticals Corporation-SmithKline Beecham Corporation Limited Partnership #1
    Inventors: Mary Ann Lukas-Laskey, Robert Ruffolo, Jr., Neil Howard Shusterman, Gisbert Sponer, Klaus Strein
  • Patent number: 5675786
    Abstract: By sampling the initial result of a query to the database, thereby producing a sampled result which is substantially smaller than the initial result, the sampled result is easier to analyse statistically and is easier to transmit across a communications medium such as a network.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: October 7, 1997
    Inventors: Neil Howard McKee, Peter Phaal
  • Patent number: 5115439
    Abstract: A gas discharge tube for a gas laser includes a discharge chamber having a first end and a second end. A cathode is mounted near the first end in a cathode region of the discharge chamber and an anode is mounted near the second end. An electromagnet induces an axial magnetic field within the discharge region, and a pole piece is mounted on the end of the electromagnet adjacent the cathode region. By using a pole piece for attenuating the axial magnetic field in the cathode region, a significant reduction in 60-60 Hz modulation of the light beam is realized, as well as a reduction of sputtering in the throat region of the discharge tube, additionally, the cathode placement relative to the throat region may be optimized leading to an increase in plasma tube efficiency. In addition, a second pole piece is mounted on the end of the electromagnetic coil, adjacent the anode region, for attenuating the axial magnetic field inside the anode region after the discharge reaches the anode.
    Type: Grant
    Filed: November 29, 1989
    Date of Patent: May 19, 1992
    Assignee: Spectra-Physics Lasers, Inc.
    Inventor: Neil Howard