Patents by Inventor Neil J. Hales

Neil J. Hales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transition metal complexes as linkers
    Patent number: 6821783
    Abstract: The invention relates to new traceless linkers which use transition metal complexes to link a &pgr;-orbital containing substrate for subsequent synthesis by, for example, combinatorial chemistry or multiple parallel synthesis (MPS) to a support.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: November 23, 2004
    Assignee: Astrazeneca AB
    Inventors: Alex C Comely, Sue E Gibson, Neil J Hales, Mark A Peplow
  • Antioestrogenic phenol derivatives
    Patent number: 4833135
    Abstract: A phenol derivative of the formulaNU-A-X-R.sup.1wherein NU is a defined bis-phenolic nucleus including a hydroxyphenyl-hydroxynaphthyl; hydroxyphenyl-hydroxy-indanyl, hydroxyphenyl-hydroxybenzothienyl or di-hydroxyphenyl-ethylene or vinylene nucleus; wherein A is alkylene, alkenylene or cycloalkylene which is interrupted by a heterocyclene linkage, wherein R.sup.1 is hydrogen, or alkyl, alkenyl, cycloalkyl, halogenoalkyl, aryl or arylalkyl, or R.sup.1 is joined to R.sup.2, and wherein X is --CONR.sup.2 --, --CSNR.sup.2 --, --NR.sup.12 CO--, --NR.sup.12 CS--, --NR.sup.12 CONR.sup.2 --, ##STR1## --SO.sub.2 NR.sup.2 -- or --CO--, or, when R.sup.1 is not hydrogen, is --NR.sup.12 COO--, --S--, --SO-- or --SO.sub.2 --, wherein R.sup.2 is hydrogen or alkyl, or R.sup.1 and R.sup.2 together form alkylene; wherein R.sup.12 is hydrogen or alkyl, and wherein R.sup.22 is hydrogen, cyano or nitro; or a salt thereof when appropriate.
    Type: Grant
    Filed: April 24, 1985
    Date of Patent: May 23, 1989
    Assignee: Imperial Chemical Industries PLC
    Inventors: Philip N. Edwards, Neil J. Hales, Derek W. Young