Patents by Inventor Neil L. Berinstein

Neil L. Berinstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210052724
    Abstract: The present invention provides methods for improving the efficacy of a vaccine in the treatment of cancer. The methods of the invention comprise the administration of at least two doses of an agent that interferes with DNA replication prior to vaccination with a survivin vaccine. Also provided are compositions for use in the methods of the invention.
    Type: Application
    Filed: July 29, 2020
    Publication date: February 25, 2021
    Applicant: Immunovaccine Technologies, Inc.
    Inventors: Marc MANSOUR, Neil L. BERINSTEIN, Genevieve Mary WEIR, Marianne M. STANFORD
  • Publication number: 20200330557
    Abstract: Aspects of the disclosure relate to methods for treating cancer, e.g., by administering to a subject having cancer a primary cell-derived biologic with multiple cytokine components in combination with an antagonist of programmed cell death-ligand 1 (PD-L1) or programmed cell death 1 (PD-1) and/or with an antagonist of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). Other aspects of the disclosure relate to methods of identifying a subject for treatment with an antagonist of PD-L1 or PD-1 and/or an antagonist of CTLA-4 or assessing the likelihood that a subject will be responsive to an antagonist of PD-L1 or PD-1 and/or an antagonist of CTLA-4.
    Type: Application
    Filed: August 18, 2017
    Publication date: October 22, 2020
    Applicant: Brooklyn Immunotherapeutics LLC
    Inventors: John W. Hadden II, Neil L. Berinstein, James E. Egan
  • Patent number: 10729766
    Abstract: The present invention provides methods for improving the efficacy of a vaccine in the treatment of cancer. The methods of the invention comprise the administration of at least two doses of an agent that interferes with DNA replication prior to vaccination with a survivin vaccine. Also provided are compositions for use in the methods of the invention.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: August 4, 2020
    Assignee: IMMUNOVACCINE TECHNOLOGIES INC.
    Inventors: Marc Mansour, Neil L. Berinstein, Genevieve Mary Weir, Marianne M. Stanford
  • Publication number: 20180289801
    Abstract: The present invention provides methods for improving the efficacy of a vaccine in the treatment of cancer. The methods of the invention comprise the administration of at least two doses of an agent that interferes with DNA replication prior to vaccination with a survivin vaccine. Also provided are compositions for use in the methods of the invention.
    Type: Application
    Filed: June 20, 2018
    Publication date: October 11, 2018
    Applicant: Immunovaccine Technologies, Inc.
    Inventors: Marc Mansour, Neil L. Berinstein, Genevieve Mary Weir, Marianne M. Stanford
  • Patent number: 10022441
    Abstract: The present invention provides methods for improving the efficacy of a vaccine in the treatment of cancer. The methods of the invention comprise the administration of at least two doses of an agent that interferes with DNA replication prior to vaccination with a survivin vaccine. Also provided are compositions for use in the methods of the invention.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: July 17, 2018
    Assignee: Immunovaccine Technologies, Inc.
    Inventors: Marc Mansour, Neil L. Berinstein, Genevieve Mary Weir, Marianne M. Stanford
  • Publication number: 20160067335
    Abstract: The present invention provides methods for improving the efficacy of a vaccine in the treatment of cancer. The methods of the invention comprise the administration of at least two doses of an agent that interferes with DNA replication prior to vaccination with a survivin vaccine. Also provided are compositions for use in the methods of the invention.
    Type: Application
    Filed: March 27, 2013
    Publication date: March 10, 2016
    Inventors: Marc Mansour, Neil L. Berinstein, Genevieve Mary Weir, Marianne M. Stanford