Abstract: The present relates to VEGF traps and VEGF mini-traps that include VEGF receptor Ig-like domains, fused to a multimerizing component, which bind to VEGF and block its interaction with the VEGF receptor. Such molecules are useful for treating angiogenic eye disorders (e.g., age-related macular degeneration), cancer and for other undesired angiogenesis.

Abstract: A heat-assisted magnetic recording head includes a laser, a near-field transducer, a primary waveguide, a secondary waveguide, and a photodiode. The laser is configured to emit electromagnetic radiation. The near-field transducer is configured to focus and emit an optical near-field. The primary waveguide configured to receive the electromagnetic radiation and propagate the electromagnetic radiation toward and proximal to the near-field transducer. The secondary waveguide configured to receive a portion of the electromagnetic radiation from the primary waveguide. The photodiode configured to receive the portion of the electromagnetic radiation from the secondary waveguide and emit a signal that represents a magnitude of the electromagnetic radiation that the laser emits.

Abstract: The present disclosure provides systems for gel electrophoresis and electrotransfer comprising one or more chambers that can removably and interchangeably receive either an electrophoresis cassette, or an electrotransfer cassette, and provides an electrical interface for both electrophoresis and electrotransfer of biomolecules. The present disclosure also provides electrophoresis devices including clamps and electrotransfer cassettes and related devices. Methods for electrophoresis and electrotransfer using the systems and devices of the disclosure are also provided.

Abstract: A female-molded double-walled underground storage tank is provided with an annulus of reduced thickness, defined by a plastic film. The film separates the inner and outer walls of the tank, providing an annulus which can be monitored to monitor the tank for failure of either the inner or the outer tank, before contamination of the exterior environment. The tank is formed of fiberglass reinforced plastic, the inner and outer walls thereof being tied together by fiberglass reinforced plastic which holds the annular film in place. The domes of the outer and inner shell are separated due to a layer of wax and alcohol applied to the inner surface of the dome of the exterior tank prior to formation of the interior tank. The spaces between the flats of the two tanks, the domes of the two tanks, and the interior of the ribs of the exterior tank are placed in fluid communication by gutters running along the length of the tank.