Abstract: The present invention provides a large-area flat plate detector. The detector includes a conversion layer which converts incident electromagnetic radiation into electric charges. The detector has a first electrode in communication with the conversion layer and a second electrode formed as a plurality of pixels arranged in a matrix. The detector includes an array of CMOS tiles, each of the tiles comprised of a plurality of pixels and having four side abuttability. The tile array is configured so that each of the tiles is separated by a spacing equal to about one pixel length from every adjacent tile and internally configured to allow for a high readout rate. Each of the tile pixels is arranged in electrical communication with and mapped in one-to-one fashion with the pixels of the second electrode. The readout electronics is capable of reading out CMOS provided data at a rate of at least 30 fps.