Patents by Inventor Neil Purdie

Neil Purdie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6737275
    Abstract: The invention presents a method designed to simultaneously measure certain unsaturated lipids and certain vitamins present either as single substances or in complex mixtures such as exist in serum and natural oils. Target lipids are free cholesterol, unsaturated cholesteryl esters; free polyunsaturated fatty acids, and their esters as triglycerides, and phospholipids. Distributions of these analytes over the broad range of serum lipoproteins from chylomicrons to high density fractions are determined using a procedure that involves a single step reaction in which the molecular unsaturations are subjected to non-enzymatic color inducing reagents. For natural oils and vitamins, the same method serves as a quality control procedure. Analytical detection is achieved using broad spectrum absorbance and/or fluorescence measurements. Measured spectra are aggregates of the absorbance contributions from each of the analytes. Data analyses follow two paths. One uses raw spectral data.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: May 18, 2004
    Assignees: The Board of Regents for Oklahoma State University, University of Cape Town
    Inventors: Neil Purdie, Justin A. Krouse, Joe Studer, Adrian D. Marais
  • Publication number: 20020160519
    Abstract: The invention presents a method designed to simultaneously measure certain unsaturated lipids and certain vitamins present either as single substances or in complex mixtures such as exist in serum and natural oils. Target lipids are free cholesterol, unsaturated cholesteryl esters; free polyunsaturated fatty acids, and their esters as triglycerides, and phospholipids. Distributions of these analytes over the broad range of serum lipoproteins from chylomicrons to high density fractions are determined using a procedure that involves a single step reaction in which the molecular unsaturations are subjected to non-enzymatic color inducing reagents. For natural oils and vitamins, the same method serves as a quality control procedure. Analytical detection is achieved using broad spectrum absorbance and/or fluorescence measurements. Measured spectra are aggregates of the absorbance contributions from each of the analytes. Data analyses follow two paths. One uses raw spectral data.
    Type: Application
    Filed: February 5, 2002
    Publication date: October 31, 2002
    Inventors: Neil Purdie, Justin A. Krouse, Joe Studer, Adrian D. Marais
  • Patent number: 5989916
    Abstract: The present invention relates to the direct quantitative determination of cholesterol and involves the formation of a spectrophotometrically active product of cholesterol obtained by contacting cholesterol with an acyl compound and a perchlorate effective to form the spectrophotometrically active product.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: November 23, 1999
    Assignee: Research Corporation Technologies, Inc.
    Inventor: Neil Purdie
  • Patent number: 5593894
    Abstract: The present invention relates to the direct quantitative determination of cholesterol and involves the formation of a spectrophotometrically active product of cholesterol obtained by contacting cholesterol with an acyl compound and a perchlorate effective to form the spectrophotometrically active product.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 14, 1997
    Assignee: Research Corporation Technologies, Inc.
    Inventor: Neil Purdie
  • Patent number: 5252488
    Abstract: Spectrophotometric methods, including the use of circular dichroism, spectrophotometric absorption detection fluorescence and derivative spectrophotometric absorption methods for use in clinical chemistry detection methods. More specifically, with the use of such spectrophotometric methods in the measurement of cholesterol levels and direct measurement of cholesterol subfractions in test samples. The invention is also concerned with providing certain absorption detection spectrophotometric apparatus and spectrophotometric reagents useful in the aforesaid methods.
    Type: Grant
    Filed: October 31, 1991
    Date of Patent: October 12, 1993
    Assignee: Research Corporation Technologies, Inc.
    Inventor: Neil Purdie
  • Patent number: 5246864
    Abstract: Spectrophotometric methods, including the use of convention spectroscopic absorption or circular dichroism, for clinical chemistry detection methods. More specifically, with the use of such spectrophotometric methods in the measurement of cholesterol levels and direct measurement of cholesterol subfractions in clinical samples, and in the measurement of lipoprotein levels in a clinical test sample, as well as in the detection of anabolic steroids and other steroid products. The invention is also concerned with providing certain CD and conventional spectrophotometric apparatus useful in each of the aforesaid chemical methods.
    Type: Grant
    Filed: January 9, 1991
    Date of Patent: September 21, 1993
    Assignee: Research Corporation Technologies, Inc.
    Inventor: Neil Purdie