Abstract: Transmissible spongiform encephalopathy (TSE) infection is treated by administration of an antibody that binds to prion dimer. A conjugate of a carrier and a fragment of a prion protein, optionally in oligomeric form and optionally having cyclic regions, is used to stimulate antibody production.

Abstract: A presser foot for a sewing machine having a base section, a support projecting upwardly from the base section for attachment to a sewing machine, and a fulling rod secured to the base section. The base section has a needle hole and a front face, a rear face, and opposed first and second sides. The lower surface of the base section has first and second surfaces each extending between the front face and rear face of the base section. The first surface is a planar surface extending substantially horizontally from the first side of the base section to a junction with the second surface. The second surface extends generally diagonally upwardly from the junction to the second side of the base section. The fulling rod extends below and spaced apart from the second surface over substantially the full length of the base section.

Abstract: A mop is provided with a fibrous yarn head, there being a ring engaging the yarn strands and forming them into loops, the ring being carried on a sleeve which is slidable and rotational over the mop handle, the handle having means projecting from one end and engaging the loop strands intermediate their ends, such that when the sleeve is in one position the strands have their intermediate portions withdrawn towards the sleeve and in cross-section define a general cardioid shape, while in another position the strands are stretched out to define a general cylindrical shape, and in the second position the strands can be wrung by a relative twisting action between the sleeve and the handle.