Abstract: A sensor interface system for providing a connection between at least one sensor and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the sensor(s) into uterine activity data signals for use by the maternal-fetal monitor. The sensor interface system of the invention preferably includes a conversion means for converting the signals from the sensor(s) into signals similar to those produced by a tocodynamometer.

Abstract: The present disclosure relates to assessment of genetic variation, and in particular to techniques for detection of chromosomal and sub-chromosomal copy number variations. In one aspect, a computer-implemented method is provided for detecting a presence or absence of copy number variation in a target sample. The method includes obtaining sequencing data for a plurality of samples, determining a first normalized coverage for each segment/element in each of the samples according to the sequencing data, determining a second normalized coverage, including a copy number, for each segment/element in each of the samples according to the first normalized coverage, classifying the copy number for each segment/element in a target set in the target sample based on rule-based approaches, machine learning based approaches, or a combination thereof, and outputting a presence or absence of a copy number variation for each segment/element in the target set in the target sample according to the classification.

Abstract: A novel clinical decision support system (CDS) helps the clinician set up, maintain, and interpret an esophageal pressure measurement. The esophageal pressure CDS (Pes CDS) would remind the clinician to do an occlusion test whenever the balloon is first inserted or changes dramatically. It could monitor the occlusion test and provide feedback on the performance and success of the occlusion test. Changes in the patient or monitored data can be tracked by looking for changes in the balloon baseline pressure, changes in the amplitude of the pressure waveform, or changes in the pattern of the Pes waveform. Having information from the ventilator will further increase the ability of the system to determine when Pes is changing unexpectedly.

Abstract: An electrode interface system for providing a connection between at least one electrode and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the electrode(s) into uterine activity data signals for use by the maternal-fetal monitor. The electrode interface system of the invention preferably includes a conversion means for converting the signals from the electrode(s) into signals similar to those produced by a tocodynometer.

Abstract: A novel clinical decision support system (CDS) helps the clinician setup, maintain, and interpret esophageal pressure measurement. The esophageal pressure CDS (Pes CDS) would remind the clinician to do an occlusion test whenever the balloon is first inserted or changes dramatically. It could monitor the occlusion test and provide feedback on the performance and success of the occlusion test. Changes in the patient or monitored data can be tracked by looking for changes in the balloon baseline pressure, changes in the amplitude of the pressure waveform, or changes in the pattern of the Pes waveform. Having information from the ventilator will further increase the ability of the system to determine when Pes is changing unexpectedly.

Abstract: A stairlift has a communication interface configured to allow communication between a user and a remote site via a variety of communication technologies whilst preventing use of the stairlift if a user is not accompanied by a means of communicating.

Abstract: A system and method for diagnosing and classifying preeclampsia-related conditions in a patient is provided. Also provided is a system and method for distinguishing preeclampsia-related conditions from other forms of hypertension that may be present in labor and delivery as well as distinguishing patients who will develop the more severe form of preeclampsia. The preeclampsia diagnosis and classification system utilizes non-invasive tests and comprises at least one sensor and a processor comprising a preeclampsia recognizer. In certain embodiments, the system further comprises a user interface.

Abstract: Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy.

Abstract: A novel clinical decision support system (CDS) helps the clinician setup, maintain, and interpret aesophageal pressure measurement. The esophageal pressure CDS (Pes CDS) would remind the clinician to do an occlusion test whenever the balloon is first inserted or changes dramatically. It could monitor the occlusion test and provide feedback on the performance and success of the occlusion test. Changes in the patient or monitored data can be tracked by looking for changes in the balloon baseline pressure, changes in the amplitude of the pressure waveform, or changes in the pattern of the Pes waveform. Having information from the ventilator will further increase the ability of the system to determine when Pes is changing unexpectedly.

Abstract: A sensor interface system for providing a connection between at least one sensor and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the sensor(s) into uterine activity data signals for use by the maternal-fetal monitor. The sensor interface system of the invention preferably includes a conversion means for converting the signals from the sensor(s) into signals similar to those produced by a tocodynamometer.

Abstract: A system and method for automated inspiratory muscle strength exercise includes software for setting a mechanical ventilator for a pressure regulated breath with an initial pressure target that is at the highest pressure setting a patient can tolerate and increasing the pressure target as tolerated.

Abstract: Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy.

Abstract: A system and method for automated inspiratory muscle strength exercise includes software for setting a mechanical ventilator for a pressure regulated breath with an initial pressure target that is at the highest pressure setting a patient can tolerate and increasing the pressure target as tolerated.

Abstract: Methods for non-invasively and accurately estimating and monitoring resistance and work of breathing parameters from airway pressure and flow sensors attached to the ventilator-dependent patient using an adaptive mathematical model are provided. These methods are based on calculations using multiple parameters derived from the above-mentioned sensors. The resistance and work of breathing parameters are important for: assessing patient status and diagnosis, appropriately selecting treatment, assessing efficacy of treatment, and properly adjusting ventilatory support.

Abstract: An event location system identifies events of interest to a user. The system uses a filter and location associated with the user to search a database of events, thereby producing an event result set representing current events near the user's location that match the user's filter. The filter may include one or more criteria, such as criteria obtained from one or more social networking profiles of the user. The location may be identified automatically, such as by using a Global Positioning System (GPS) module. The system may automatically update the event result set over time and as the user's location changes so that the event result set is always up-to-date and reflects the user's current location.

Abstract: Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy.

Abstract: A sensor interface system for providing a connection between at least one sensor and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the sensor(s) into uterine activity data signals for use by the maternal-fetal monitor. The sensor interface system of the invention preferably includes a conversion means for converting the signals from the sensor(s) into signals similar to those produced by a tocodynamometer.

Abstract: An electrode interface system for providing a connection between at least one electrode and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the electrode(s) into uterine activity data signals for use by the material monitor. The electrode interface system of the invention preferably includes a conversion means for converting the signals from the electrode(s) into signals similar to those produced by a tocodynometer.

Abstract: A sensor interface system for providing a connection between at least one sensor and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the sensor(s) into uterine activity data signals for use by the maternal-fetal monitor. The sensor interface system of the invention preferably includes a conversion means for converting the signals from the sensor(s) into signals similar to those produced by a tocodynamometer.

Abstract: An electrode interface system for providing a connection between at least one electrode and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the electrode(s) into uterine activity data signals for use by the maternal-fetal monitor. The electrode interface system of the invention preferably includes a signal converter for processing the signals from the electrode(s) into signals similar to those produced by a tocodynometer.