Abstract: Cutting members including a body including a first surface, a second surface spaced from the first surface and extending in a plane substantially aligned with the first surface, a leading surface extending between the first surface and the second surface, the leading surface extending in a plane transverse to the first surface and the second surface, and an attaching surface distal the leading surface, the attaching surface extending between the first surface and the second surface and a plurality of abrasive elements integrated in the body. In some examples, the cutting member is configured as a cylindrical drill bit and the abrasive elements are aligned transverse the leading surface. In some further examples, the cutting member is configured as a circular disk and the abrasive elements are aligned transverse the first surface and the second surface.

Abstract: The invention provides an aqueous shampoo composition comprising, in admixture: (i) a first anionic surfactant in which the ratio between the molecular weights of the polar (hydrophilic) and non-polar (hydrophobic) parts of the molecule is less than 1.5; (ii) a second anionic surfactant in which the ratio between the molecular weights of the polar (hydrophilic) and non-polar (hydrophobic) parts of the molecule is greater than 1.5, and (iii) a cationic polymer having a molecular weight of at least 100,000 Dalton and a cationic charge density of at least 0.5 meq/g; in which the weight ratio of (i):(ii) ranges from 3:1 to 1:3. Shampoo compositions according to the invention demonstrate reduced extensional viscosity (i.e. are less “stringy”). They also provide for the delivery of a significantly increased level of conditioning without any significant increase in product stringiness.

Abstract: A combination cancer therapy based upon catechins, the major biologically active polyphenol in plant products, including green tea extract, and one or more chemotherapeutic agents. A common complication of cancer chemotherapy is neutropenia, and in spite of advances in its prophylactic management is a major cause of risk for the development of serious microbial infections leading to increased morbidity and mortality in both humans and animals. The use of cathechins such as those found in green tea (Camellia sinensis), including but not limited to epigallocatechin gallate (EGCG) as nontoxic adjuvant to aid in the prevention of opportunistic microbial infections in patients undergoing immunosuppressive chemotherapy is a novel application. Also contemplated are methods using catechins to ameliorate the immunosuppressive effects of cancer chemotherapy by administering the compound to a patient in need thereof.

Abstract: Aqueous hair conditioning compositions comprising a) from 1% to 50% by weight of a cleansing surfactant, b) discrete, dispersed droplets comprising a water insoluble silicone conditioning oil, with a Sauter mean diameter from 2 to 100 micrometres and c) a surface active block copolymer according to Formula (I): HO(CH2CH2O)m[—Si(CH3)2?O?]n(CH2CH20)m H wherein m is 30 or more, n is 5 or more and the ratio n/m is from 0.1 to 1.2, provide improved conditioning of hair tips.

Abstract: Aqueous hair cleansing and conditioning compositions are disclosed comprising comprising; a) from 1% to 50% by weight of a cleansing surfactant, b) discrete, dispersed droplets comprising a water-insoluble silicone conditioning oil characterised in that the mean diameter of the droplets (D3,2) is from 2 to 100 micrometres and c) a surface active block copolymer with a mean molecular weight of 4000 unified atomic mass units or more comprising polyethyleneoxide blocks and polypropyleneoxide blocks, wherein each block consists of 2 or more ethylene oxide or propylene oxide monomer units and wherein the mean number propylene monomer units in the block copolymer is 25 or more.

Abstract: An aqueous hair conditioner composition comprising: a) a cationic conditioning surfactant, b) discrete, dispersed droplets comprising a water-insoluble conditioning oil and c) a block copolymer with a mean molecular weight of 1000 unified atomic mass units or more, comprising polyethyleneoxide and polypropyleneoxide blocks selected from the group consisting of (i) poloxamers according to formula (I), wherein the mean value of (y) is from 18 to 60 and the mean value (x) is from 7 to 140 such that the mean value of the ratio (x/y) is from 0.4 to 3.0 and (ii) poloxamines according to formula (II), wherein the mean value of (a) is 2 or more and the mean value of (b) is 2 or more.

Abstract: Hair washing compositions are disclosed which comprise cleansing surfactant, water, first and second cationic polymers having at pH7 a charge density from 0.2 to 1 meq/gm and from 1.3 to 3 meq/gm respectively, and droplets of a water-insoluble conditioning oil of diameter 4 micrometres or less. The compositions provide cleansing with conditioning and low friction and ease of combing for wet and dry hair.

Abstract: An aqueous hair conditioning composition comprising discrete, dispersed droplets of a hydrophobic conditioning oil with a mean droplet diameter (D3,2) of 4 micrometres or less, a cationic deposition polymer and a block copolymer of ethylene glycol and propylene glycol according to the Formula (I) with the mean value of y from 10 to 60 and the values of x and z both from 1 to 150, or a block copolymer according to Formula (II) wherein the mean value of a is 2 or more and the mean value of b is 2 or more.