Abstract: A series of substituted imidazo[1,2-b]pyridazine derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

Abstract: Rack mounting adapters with airflow management are disclosed. In one embodiment, rack mounting adapter apparatus comprises: a housing configured to adapt an electrical component chassis subrack configured for side-to-side airflow cooling to mount to an equipment rack; and an airflow management system within the housing that converts the side-to-side airflow cooling of the electrical component chassis subrack to a front-to-back airflow configuration that intakes air from a front of the equipment rack and exhausts air to a back of the equipment rack.

Abstract: A calibration sub-system for calibrating a unit of a distributed antenna system is provided. The calibration sub-system includes a signal generator, a receiver, and a processor. The signal generator provides test signals to a communication path that are generated based on modification schemes for an in-phase signal component (“I component”) or a quadrature signal component (“Q component”). The receiver receives output signals generated from test signals. The processor determines output power values for an undesirable signal component of the output signals. Each output power value is a Taylor series function or a polynomial function of a respective modification scheme for the I or Q component of the respective test signal. The processor determines an optimal modification scheme for the I or Q component that minimizes an output power of the undesirable signal component. An output value of the function is minimized by having the optimal modification scheme as an input.

Abstract: A calibration sub-system for calibrating a unit of a distributed antenna system is provided. The calibration sub-system includes a signal generator, a receiver, and a processor. The signal generator provides test signals to a communication path that are generated based on modification schemes for an in-phase signal component (“I component”) or a quadrature signal component (“Q component”). The receiver receives output signals generated from test signals. The processor determines output power values for an undesirable signal component of the output signals. Each output power value is a Taylor series function or a polynomial function of a respective modification scheme for the I or Q component of the respective test signal. The processor determines an optimal modification scheme for the I or Q component that minimizes an output power of the undesirable signal component. An output value of the function is minimized by having the optimal modification scheme as an input.

Abstract: A repeat prescription ordering system for allowing patients requiring resupply of medication or medical products to access a server using a portable communications and data processing device such as a smart phone or personal digital assistant. The server supplies to the patient a list of medication and medical products which they are authorized to order. The patient can select the products required, and the order is logged by the server and allocated to a supplier for completion of the order. The server maintains an estimate of the amount of medication or medical product held by the patient, this being based on the prescribed dosage regimen and information entered by the patient on their usage and, optionally, on checks on their own health. The patient may be alerted when the estimate indicates that their supplies are running low. The estimate is allowed to go below zero, this implying a possible departure from the prescribed medication regimen.

Abstract: A method and apparatus for locating a feature in a photoplethysmograph or blood pressure signal, comprising a series of signal complexes each having a principal peak (or equivalent trough), is disclosed. The signal is processed to identify a reference point on the upslope of a principal peak. The signal is then searched for the feature in the vicinity of the reference point.