Patents by Inventor Neil W. Loomis
Neil W. Loomis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6786874Abstract: The present invention involves apparatus and methods for use in collecting bodily fluids, such as interstitial fluids, from the epidermal layer of an animal. A preferred apparatus includes a pressure head and, optionally, a holder therefor for supplying a positive pressure to the head. The methods include the application of a positive pressure to the area surrounding an epidermal site from which stratum corneum has been breached, such as by laser ablation, to cause bodily fluids, such as interstitial fluids, to exude from the site and collecting the fluids exuding therefrom.Type: GrantFiled: September 13, 2002Date of Patent: September 7, 2004Assignee: Abbott LaboratoriesInventors: John P. Grace, Neil W. Loomis, Thomas G. Schapira, Sie Ting Wong, Kristin M. Noonan, Michael G. Lowery, Pete M. Bojan, Daniel P. Schmidt, Tung-Ming Huang, Robert G. Hiltibran, Mark R. Pope, John J. Kotlarik, Brian Joseph Tarkowski, David Dean Cunningham
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Patent number: 6679841Abstract: An article capable of both collecting interstitial fluid and detecting an analyte in that fluid and a method for use of that article. Preferably, the article is also capable of measuring the amount of analyte in the interstitial fluid. The article can be used in conjunction with a meter that contains an appropriate detection element for determining the amount of analyte in the interstitial fluid.Type: GrantFiled: June 15, 2001Date of Patent: January 20, 2004Assignee: Abbott LaboratoriesInventors: Peter M. Bojan, Timothy P. Henning, Neil W. Loomis, Mark R. Pope, Jonathan A. Eppstein
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Publication number: 20030114774Abstract: The present invention involves apparatus and methods for use in collecting bodily fluids, such as interstitial fluids, from the epidermal layer of an animal. A preferred apparatus includes a pressure head and, optionally, a holder therefor for supplying a positive pressure to the head. The methods include the application of a positive pressure to the area surrounding an epidermal site from which stratum corneum has been breached, such as by laser ablation, to cause bodily fluids, such as interstitial fluids, to exude from the site and collecting the fluids exuding therefrom.Type: ApplicationFiled: September 13, 2002Publication date: June 19, 2003Inventors: John P. Grace, Neil W. Loomis, Thomas G. Schapira, Sie Ting Wong, Kristin M. Noonan, Michael G. Lowery, Pete M. Bojan, Daniel P. Schmidt, Tung-Ming Huang, Robert G. Hiltibran, Jon G. Hiltibran, Mark R. Pope, John J. Kotlarik, Brian Joseph Tarkowski, David Dean Cunningham
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Patent number: 6468229Abstract: The present invention involves apparatus and methods for use in collecting bodily fluids, such as interstitial fluids, from the epidermal layer of an animal. A preferred apparatus includes a pressure head and, optionally, a holder therefor for supplying a positive pressure to the head. The methods include the application of a positive pressure to the area surrounding an epidermal site from which stratum corneum has been breached, such as by laser ablation, to cause bodily fluids, such as interstitial fluids, to exude from the site and collecting the fluids exuding therefrom.Type: GrantFiled: January 26, 2001Date of Patent: October 22, 2002Assignee: Abbott LaboratoriesInventors: John P. Grace, Neil W. Loomis, Thomas G. Schapira, Sie Ting Wong, Kristin M. Noonan, Michael G. Lowery, Pete M. Bojan, Daniel P. Schmidt, Tung-Ming Huang, Robert G. Hiltibran, Mark R. Pope, John J. Kotlarik, Brian Joseph Tarkowski, David Dean Cunningham
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Publication number: 20020099308Abstract: An article capable of both collecting interstitial fluid and detecting an analyte in that fluid and a method for use of that article. Preferably, the article is also capable of measuring the amount of analyte in the interstitial fluid. The article can be used in conjunction with a meter that contains an appropriate detection element for determining the amount of analyte in the interstitial fluid.Type: ApplicationFiled: June 15, 2001Publication date: July 25, 2002Inventors: Peter M. Bojan, Timothy P. Henning, Neil W. Loomis, Mark R. Pope, Jonathan A. Eppstein
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Patent number: 6245060Abstract: A method for increasing the permeability of the stratum corneum by means of a source of light, preferably a laser, more preferably a pulsed laser. By increasing the permeability of the stratum corneum, access to the interstitial fluid is achieved, thereby enabling measurement of analytes in the interstitial fluid. In one aspect, the method comprises the steps of: (a) providing a source of light having a wavelength of from about 930 nm to about 1040 nm; and (b) exposing a region of the stratum corneum of the patient to said source of light for a period of time sufficient to form an opening in the stratum corneum.Type: GrantFiled: December 27, 1999Date of Patent: June 12, 2001Assignee: Abbott LaboratoriesInventors: Neil W. Loomis, Peter M. Bojan, Timothy P. Henning, Mark R. Pope, Andrew J. Muetterties
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Patent number: 6027496Abstract: A method for increasing the permeability of the stratum corneum by means of a source of light, preferably a laser, more preferably a pulsed laser. By increasing the permeability of the stratum corneum, access to the interstitial fluid is achieved, thereby enabling measurement of analytes in the interstitial fluid. In one aspect, the method comprises the steps of:(a) providing a source of light having a wavelength of from about 930 nm to about 1040 nm; and(b) exposing a region of the stratum corneum of the patient to said source of light for a period of time sufficient to form an opening in the stratum corneum.Type: GrantFiled: March 25, 1997Date of Patent: February 22, 2000Assignee: Abbott LaboratoriesInventors: Neil W. Loomis, Peter M. Bojan, Timothy P. Henning, Mark R. Pope, Andrew J. Muetterties
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Patent number: 5952173Abstract: The present invention relates to analytical devices for determining the presence or amount of an analyte in a test sample. The analytical devices comprise an inlet port, a vent, a channel, and an array of structures. The structures have immobilized reagent covalently or non-covalently attached to the surface of the structures. The immobilized reagent captures analyte in the test sample where it is detected by a detection system. The present invention also provides methods and reagents for performing assays utilizing the analytical devices of the present invention. The present invention also provides methods of manufacturing the analytical devices of the present invention.Type: GrantFiled: August 21, 1997Date of Patent: September 14, 1999Assignee: Abbott LaboratoriesInventors: Douglas D. Hansmann, John P. Grace, Michael G. Lowery, Gary M. Oosta, Neil W. Loomis, Eric B. Shain, Thomas G. Schapira
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Patent number: 5707799Abstract: The present invention relates to analytical devices for determining the presence or amount of an analyte in a test sample. The analytical devices comprise an inlet port, a vent, a channel, and an array of structures. The structures have immobilized reagent covalently or non-covalently attached to the surface of the structures. The immobilized reagent captures analyte in the test sample where it is detected by a detection system. The present invention also provides methods and reagents for performing assays utilizing the analytical devices of the present invention. The present invention also provides methods of manufacturing the analytical devices of the present invention.Type: GrantFiled: September 30, 1994Date of Patent: January 13, 1998Assignee: Abbott LaboratoriesInventors: Douglas D. Hansmann, John P. Grace, Michael G. Lowery, Gary M. Oosta, Neil W. Loomis, Eric B. Shain, Thomas G. Schapira
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Patent number: 4491732Abstract: In a modular solid state detector of the type including a scintillator and diodes for converting x-ray flux to a measurable electrical signal, the diodes are mounted out of the path of incident x-radiation to minimize noise and to limit degradation. The resulting configuration reduces efficiency because the active diode area is limited and the length of the light path between the scintillator and diode is increased. In order to compensate for that reduction in efficiency, optical potting material is used to join the scintillator to the diodes in order to minimize light attenuation between those elements. In addition, the outer surface of the cured optical potting material is coated with a thin specular layer of silver to keep the light within the optical potting material and thus most efficiently reflected from the scintillator to the diode.Type: GrantFiled: August 25, 1982Date of Patent: January 1, 1985Assignee: General Electric CompanyInventors: Dennis H. Pritzkow, Neil W. Loomis, Thomas M. Golner, David M. Hoffman
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Patent number: 4417144Abstract: A modular solid-state detector cell which intimately associates a scintillator body with a pair of photoresponsive semiconductors so as to present on a single collimator plate all of the elements necessary for transforming incident X-radiation into a measurable electrical signal. The detector is provided with a precision slotted mounting arrangement for receiving the unit cells, and the cells when positioned within the detector assembly have the photoresponsive semiconductors enclosed within the light tight cell. The unit is adaptable to off-line testing of the separate cells for screening before assembly.Type: GrantFiled: February 23, 1981Date of Patent: November 22, 1983Assignee: General Electric CompanyInventors: David M. Hoffman, Neil W. Loomis, Ralph C. Ehlert, Peter S. Shelley