Abstract: The present invention provides improved devices for inserting solid materials under a tissue, the devices particularly containing a penetration guide means designed to facilitate the implantation by limiting the insertion of the implants to positions under and substantially parallel to the plane of the tissue.

Abstract: An ophthalmic applicator device for mechanically inserting solid medicaments in the form of inserts into the cul-de-sac of the eye, comprising an elongated tip of non-toxic, pliable material terminating in a groove through an end of said tip sufficient to form two flexible, opposed termini of said tip whereby said insert is releasably gripped by frictional engagement between said termini; said groove having cross-sectional conformation and dimensions sufficient to releasably grip said insert, and at least one dimension sufficiently less than the greatest dimension of said insert to result in removal of said insert from the ophthalmic applicator device by contact of said insert with the cul-de-sac of the eye; and a handle attached to said tip at the end of said tip opposite said termini, and forming an interior angle therewith of from about 30.degree. to about 120.degree..

Abstract: A dispensing and packaging system for pellets such as ampules or vials. The system comprises an elongated resilient plastic tube in which the pellets are arranged in a line. The tube is of slightly smaller inner diameter than the pellets; and it is slit along its length so that it expands circumferentially to accomodate the pellets. The plastic material of the tube is sufficiently flexible and resilient at room temperatures to neck down in regions between adjacent pellets or in regions of the pellets which are of small diameter. This necking down provides restraint against axial movement of the pellets to hold them securely in the tube while allowing them to be dispensed individually with a minimum of difficulty.

Abstract: A dispensing container for pellets such as capsules and pills and comprising an elongated tubular member holding the pellets in a line, the member being slit helically along its length and being resilient so that when twisted about its longitudinal axis the slit opens for dispensing a pellet.