Patents by Inventor Nels Pederson

Nels Pederson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of supplementing culture media to prevent undesirable amino acid substitutions
    Patent number: 9096879
    Abstract: The present invention relates to methods of reducing substitution of amino acids during the production of polypeptides of interest in mammalian cells. By varying the concentration of amino acids in the culture medium, heterogeneity of the polypeptide's amino acid sequence is decreased, leading to higher yields of functional protein.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: August 4, 2015
    Assignee: BIOGEN MA INC.
    Inventors: Anurag Khetan, Yao-ming Huang, Jana Dolnikova, Nels Pederson, Helena Yusuf-Makagiansar, Paul Chen, Thomas Ryll
  • Method of Supplementing Culture Media to Prevent Undesirable Amino Acid Substitutions
    Publication number: 20130096283
    Abstract: The present invention relates to methods of reducing substitution of amino acids during the production of polypeptides of interest in mammalian cells. By varying the concentration of amino acids in the culture medium, heterogeneity of the polypeptide's amino acid sequence is decreased, leading to higher yields of functional protein.
    Type: Application
    Filed: November 24, 2009
    Publication date: April 18, 2013
    Applicant: Biogen Idec MA inc.
    Inventors: Anurag Khetan, Yao-ming Huang, Jana Dolnikova, Nels Pederson, Helena Yusuf-Makagiansar, Paul Chen, Thomas Ryll
  • Neublastin expression constructs
    Publication number: 20050158824
    Abstract: A method of producing a secreted neublastin polypeptide using a heterologous signal sequence is disclosed. The secreted neublastin does not contain a neublastin pro sequence.
    Type: Application
    Filed: October 1, 2004
    Publication date: July 21, 2005
    Inventors: Nels Pederson, William Sisk