Patents by Inventor Nelsi Zaccheroni

Nelsi Zaccheroni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230122419
    Abstract: A method for detecting nano- and micro-plastics in an aqueous sample suspected of being polluted with nano- or micro-plastics is provided. The method is based on interaction of the nano- and micro-plastics with hyaluronic acid functionalized with a luminescent or fluorescent dye. The luminescent or fluorescent dye is Rhodamine B or the metallorganic complex Ru(bpy)32+.
    Type: Application
    Filed: January 19, 2021
    Publication date: April 20, 2023
    Inventors: Damiano GENOVESE, Luca PRODI, Enrico RAMPAZZO, Nelsi ZACCHERONI
  • Patent number: 9616141
    Abstract: The present invention relates to silica nanoparticles comprising at least two dyes. Said dyes have a respective relationship of donor-acceptor couple in an energy transfer process and have a molar absorption coefficient ?10,000 M?1 cm?1 for the considered spectral region, a fluorescence quantum yield ?0.01, good overlap integral, according to the Förster theory, between said donor and said acceptor dye; said active compounds may be lipophilic or may present a functionality useful for the introduction of a trialkoxysilane moiety. The dyes provide an efficient energy transfer process. Said nanoparticles are useful as probes in the field of medicine, in particular therapy and diagnostics, more particularly in theranostics, and in the field of analytical chemistry.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: April 11, 2017
    Assignee: ALMA MATER STUDIORUM UNIVERSITA DI BOLOGNA
    Inventors: Sara Bonacchi, Marco Montalti, Luca Prodi, Nelsi Zaccheroni, Riccardo Juris, Damiano Genovese, Enrico Rampazzo
  • Patent number: 8771642
    Abstract: Nanoparticles, which are luminescent and/or electroactive and/or suitable for MRI (magnetic resonance imaging and/or PET (positron emission tomography) applications, comprise a micelle, which has a hydrophilic shell and an hydrophobic central portion, and a polysilicate core; the micelle comprises a plurality of molecules of a functionalized surfactant having the following structure: M1-Hydro1-Lipo-Hydro2-M2 wherein Lipo indicates a hydrophobic chain; Hydro1 ed Hydro2 indicate, each, a respective hydrophilic chain; M1 ed M2 represent respective recognition functionalities.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: July 8, 2014
    Assignee: Alma Mater Studiorum—Universita' Di Bologna
    Inventors: Sara Bonacchi, Riccardo Juris, Marco Montalti, Luca Prodi, Enrico Rampazzo, Nelsi Zaccheroni
  • Publication number: 20130315835
    Abstract: The present invention relates to silica nanoparticles comprising at least two dyes. Said dyes have a respective relationship of donor-acceptor couple in an energy transfer process and have a molar absorption coefficient ?10,000 M?1 cm?1 for the considered spectral region, a fluorescence quantum yield ?0.01, good overlap integral, according to the Förster theory, between said donor and said acceptor dye; said active compounds may be lipophilic or may present a functionality useful for the introduction of a trialkoxysilane moiety. The dyes provide an efficient energy transfer process. Said nanoparticles are useful as probes in the field of medicine, in particular therapy and diagnostics, more particularly in theranostics, and in the field of analytical chemistry.
    Type: Application
    Filed: October 13, 2011
    Publication date: November 28, 2013
    Applicant: ALMA MATER STUDIORUM UNIVERSITÀ DI BOLOGNA
    Inventors: Sara Bonacchi, Marco Montalti, Luca Prodi, Nelsi Zaccheroni, Riccardo Juris, Damiano Genovese, Enrico Rampazzo
  • Publication number: 20130301679
    Abstract: Use for measuring temperatures of a coordination complex presenting formula I, wherein M1, M2, M3, M4, M5 are chosen, each independently of the others, in the group consisting of: CuI, AgI, AuI, PdII; n is equal to the sum of the oxidation states of M1, M2, M3, M4, M5 minus 3; II represents a respective portion of each tridentate ligand having the formula III in which R1 is chosen in the group consisting of: Ph, C1-C4 alkyl, halo-alkyl C1-C4 substituted phenyl; R2 is chosen in the group consisting of: Ph, C1-C4 alkyl, C1-C4 halo-alkyl-, substituted phenyl; R3 is chosen in the group consisting of: C3-C18 alkyl, benzyl, substituted benzyl, C1-C20 hydroxy-alkyl, C1-C20 alkoxy silane.
    Type: Application
    Filed: October 26, 2011
    Publication date: November 14, 2013
    Applicants: UNIVERSITA ' DELGI STUDI DI PARMA, ALMA MATER STUDIORUM- UNIVERSITA' DI BOLOGNA
    Inventors: Sara Bonacchi, Marco Montalti, Luca Prodi, Nelsi Zaccheroni, Francesco Zerbetto, Matteo Calvaresi, Daniele Alessandro Cauzzi
  • Publication number: 20110274621
    Abstract: Nanoparticles, which are luminescent and/or electroactive and/or suitable for MRI (magnetic resonance imaging and/or PET (positron emission tomography) applications, comprise a micelle, which has a hydrophilic shell and an hydrophobic central portion, and a polysilicate core; the micelle comprises a plurality of molecules of a functionalized surfactant having the following structure: M1-Hydro1-Lipo-Hydro2-M2 wherein Lipo indicates a hydrophobic chain; Hydro1 ed Hydro2 indicate, each, a respective hydrophilic chain; M1 ed M2 represent respective recognition functionalities.
    Type: Application
    Filed: July 31, 2009
    Publication date: November 10, 2011
    Applicant: ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA
    Inventors: Sara Bonacchi, Riccardo Juris, Marco Montalti, Luca Prodi, Enrico Rampazzo, Nelsi Zaccheroni
  • Publication number: 20110262356
    Abstract: Luminescent and/or electroactive nanoparticles suitable for MRI (Magnetic Resonance Imaging) and/or PET (Positron Emission Tomography) are prepared by mixing luminescent or electroactive compounds and ethyl oxide/propyl oxide block-copolymers in an organic solvent, which is thereafter evaporated in order to obtain a residue; and by hydrolyzing-condensating tetraalkoxysilanes in an aqueous solution in the presence of the residue; the obtained nanoparticles show no or a negligible release of the luminescent or electroactive compounds and are useful for bio-analytic and bio-medic applications.
    Type: Application
    Filed: July 31, 2009
    Publication date: October 27, 2011
    Applicants: CYANAGEN S.R.L., ALMA MASTER STUDIORUM-UNIVERSITA' DI BOLOGNA
    Inventors: Sara Bonacchi, Ricarrdo Juris, Marco Montalti, Luca Prodi, Enrico Rampazzo, Nelsi Zaccheroni, Leopoldo Della Ciana, Serena Fabbroni, Stafano Grilli, Ettore Marzocchi