Patents by Inventor Nelson Arispe

Nelson Arispe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Histidine related compounds for identifying and blocking amyloid beta ion channels
    Patent number: 8476240
    Abstract: The present disclosure relates to amyloid beta (A?) channels and the diseases and disorders caused by abnormal activity in these channels, such as Alzheimer's disease, Lewy body dementia, inclusion body myositis, or cerebral amyloid angiopathy. The disclosure provides compositions and methods that block A? channel activity and/or reduce A?-induced toxicity in a cell. Compositions comprised of compounds having histidine coordinating capacity are used in methods to prevent, reduce, or eliminate damage caused by A? ion channels.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: July 2, 2013
    Assignee: The Henry M. Jackson Foundation for The Advancement of Military Medicine, Inc.
    Inventor: Nelson Arispe
  • HISTIDINE RELATED COMPOUNDS FOR IDENTIFYING AND BLOCKING AMYLOID BETA ION CHANNELS
    Publication number: 20110015139
    Abstract: The present disclosure relates to amyloid beta (A?) channels and the diseases and disorders caused by abnormal activity in these channels, such as Alzheimer's disease, Lewy body dementia, inclusion body myositis, or cerebral amyloid angiopathy. The disclosure provides compositions and methods that block AO channel activity and/or reduce A?-induced toxicity in a cell. Compositions comprised of compounds having histidine coordinating capacity are used in methods to prevent, reduce, or eliminate damage caused by A? ion channels.
    Type: Application
    Filed: March 18, 2009
    Publication date: January 20, 2011
    Applicant: he Henry M. JAckson Foundation for the Advancement of Military Medicine, Inc.
    Inventor: Nelson Arispe