Patents by Inventor Nelson D. Horseman

Nelson D. Horseman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150196507
    Abstract: The present invention is a method for increasing serotonin activity in mammary glands such that involution of milk secretion of the same mammary glands occurs. The present invention further is a composition that can be implanted, or infused into the mammary glands to cause involution of milk secretion.
    Type: Application
    Filed: January 14, 2015
    Publication date: July 16, 2015
    Inventors: Nelson D. Horseman, Robert J. Collier, Aaron M. Marshall, Laura Hernandez Baumgard
  • Patent number: 8987336
    Abstract: The present invention is a method for increasing serotonin activity in mammary glands such that involution of milk secretion of the same mammary glands occurs. The present invention further is a composition that can be implanted, or infused into the mammary glands to cause involution of milk secretion.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: March 24, 2015
    Assignee: Amelgo, LLC
    Inventors: Nelson D. Horseman, Robert J. Collier, Aaron M. Marshall, Laura Hernandez Baumgard
  • Patent number: 8133916
    Abstract: The present invention is a method for increasing serotonin activity in mammary glands such that involution of milk secretion of the same mammary glands occurs. The present invention further is a composition that can be implanted, or infused into the mammary glands to cause involution of milk secretion.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: March 13, 2012
    Assignee: Amelgo, LLC
    Inventors: Nelson D. Horseman, Robert J. Collier, Aaron M. Marshall, Laura Hernandez Baumgard
  • Publication number: 20100311117
    Abstract: A recombinant intestinal nucleic acid is provided. One embodiment of the present invention contemplates the use of a gut-specific promoter, wherein a promoter can be the chicken intestinal fatty acid binding protein promoter region. A method for making a transgenic bird is also disclosed by transfecting a bird with a vector comprising a recombinant nucleic acid comprising a chicken intestinal fatty acid binding protein promoter region operably linked to a heterologous nucleic acid expressing a desired polypeptide to be expressed in the gut tissue of an avian.
    Type: Application
    Filed: September 3, 2009
    Publication date: December 9, 2010
    Inventors: NELSON D. HORSEMAN, SCOTT L. PRATT
  • Patent number: 7241797
    Abstract: The invention relates generally to the use of pharmaceutical compositions to increase milk production alone or in combination with certain biological active ingredients. Specifically, the method relates to the use of pharmaceutical compositions that will act on the feedback of the intrinsic regulatory pathway in the mammalian mammary gland. The present invention provides for as a method of increasing bovine milk production as well as a method of correcting certain human lactation abnormalities. Preferably, the compounds used in the methods of the present invention are one or more active agents capable of inhibiting peripheral aromatic amino acid decarboxylase (AADC) enzymes, peripheral tryptophan hydroxylase (TPH) enzymes, peripheral serotonin (5-HT) enzymes, or a combination of enzymes thereof.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: July 10, 2007
    Assignee: University of Cincinnati
    Inventor: Nelson D. Horseman
  • Patent number: 7135562
    Abstract: A recombinant nucleic acid is provided having an avian promoter. One embodiment of the present invention contemplates the use of a gut-specific promoter, wherein a promoter can be the chicken intestinal fatty acid binding protein promoter region. A method for making a transgenic bird is also disclosed by transfecting a bird with a vector comprising a recombinant nucleic acid comprising a chicken intestinal fatty acid binding protein promoter region operably linked to a heterologous nucleic acid expressing a desired polypeptide to be expressed in the gut tissue of an avian.
    Type: Grant
    Filed: March 14, 2002
    Date of Patent: November 14, 2006
    Assignee: University of Cincinnati
    Inventors: Nelson D. Horseman, Scott L. Pratt
  • Publication number: 20030177516
    Abstract: A recombinant nucleic acid is provided having an avian promoter. One embodiment of the present invention contemplates the use of a gut-specific promoter, wherein a promoter can be the chicken intestinal fatty acid binding protein promoter region. A method for making a transgenic bird is also disclosed by transfecting a bird with a vector comprising a recombinant nucleic acid comprising a chicken intestinal fatty acid binding protein promoter region operably linked to a heterologous nucleic acid expressing a desired polypeptide to be expressed in the gut tissue of an avian.
    Type: Application
    Filed: March 14, 2002
    Publication date: September 18, 2003
    Inventors: Nelson D. Horseman, Scott L. Pratt
  • Publication number: 20030139420
    Abstract: The invention relates generally to the use of pharmaceutical compositions to increase milk production alone or in combination with certain biological active ingredients. Specifically, the method relates to the use of pharmaceutical compositions that will act on the feedback of the intrinsic regulatory pathway in the mammalian mammary gland. The present invention provides for as a method of increasing bovine milk production as well as a method of correcting certain human lactation abnormalities. Preferably, the compounds used in the methods of the present invention are one or more active agents capable of inhibiting peripheral aromatic amino acid decarboxylase (AADC) enzymes, peripheral tryptophan hydroxylase (TPH) enzymes, peripheral serotonin (5-HT) enzymes, or a combination of enzymes thereof.
    Type: Application
    Filed: January 22, 2003
    Publication date: July 24, 2003
    Inventor: Nelson D. Horseman