Patents by Inventor Nelson Johansen

Nelson Johansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARTIFICIAL EXPRESSION CONSTRUCTS FOR MODULATING GENE EXPRESSION IN CELLS WITHIN THE SPINAL CORD
    Publication number: 20260226502
    Abstract: Artificial expression constructs for modulating gene expression in targeted central nervous system cell types are described. The artificial expression constructs can be used to express synthetic genes or modify gene expression in the spinal cord spinal motor neurons including Spp1 spinal motor neurons, Parg spinal motor neurons, Ogdh1 spinal motor neurons, or ChAT spinal motor neurons; alpha motor neurons including Chodl spinal motor neurons; gamma motor neurons; spinal excitatory motor neurons including Mafa excitatory neurons, Esrrg Trhr excitatory neurons, Slc17a6 spinal cord excitatory neurons; spinal inhibitory neurons including Slc6a5 spinal cord inhibitory neurons; pan spinal neurons including Esrrg spinal motor neurons and pan spinal cord types; cerebrospinal fluid-contacting neurons including Poln spinal motor neurons; and spinal non-neuronal cells including astrocytes and oligodendrocytes.
    Type: Application
    Filed: February 2, 2024
    Publication date: August 6, 2026
    Applicant: Allen Institute
    Inventors: Tanya Daigle, Yuan Gao, Nelson Johansen, Edward Sebastian Lein, Boaz P. Levi, John K. Mich, Bosiljka Tasic, Jonathan Ting, Zizhen Yao, Hongkui Zeng