Patents by Inventor Nenad S. Markovic

Nenad S. Markovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040137551
    Abstract: Cervical Acid Phosphatase-Papanicolaou Test Kit (CPK) is an assembly of reagents, controls and instructions for visualization of cervical acid phosphatase on smears or monolayers of cervical specimens, and for performing the CAP-PAP Test (CPT).
    Type: Application
    Filed: January 13, 2003
    Publication date: July 15, 2004
    Inventors: Nenad S. Markovic, Olivera Markovic
  • Patent number: 5620961
    Abstract: A specialized derivative of fructose in which the compound is a fructose ester complexed with .beta.-cyclodextrin. Preferably, the fructose derivative is fructosehexanoate .beta.-cyclodextrin complex, and more preferably the fructose derivative is fructose-1-O-hexanoate .beta.-cyclodextrin complex. Fructose pentanoate and fructose heptanoate .beta.-cyclodextrin complexes are also included within the scope of the invention, and the fructose ester and the .beta.-cyclodextrin must be combined in approximately molar equivalent amounts. The present invention also includes a method for treating animals and humans with the instant fructose derivatives, to protect against tissue damage caused by doxorubicin cytotoxicity (particularly doxorubicin-induced cardiomyopathy or mucositis), ischemia, radiation damage and other sources of free oxygen radical cellular damage to the tissue of living animals and humans.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: April 15, 1997
    Inventors: Nenad S. Markovic, Olivera T. Markovic
  • Patent number: 5358855
    Abstract: A cyto(histo)chemical technique for determining inosine 5'-monophosphate dehydrogenase (IMPD) presence and concentration within one or more morphologically classified or classifiable cells taken from an animal or a human subject. Cell monolayers are prepared, fixed and stained according to a specified procedure in which inosine 5'-monophosphate (as enzyme substrate), nicotinamide adenine dinucleotide (NAD), phenazine methosulfate (PMS) and nitro blue tetrazolium (NBT) as a diazonium salt together produce a granular, dark blue deposit of formazan generally proportional to the IMPD activity in the cell. Cells are evaluated either visually or by image analysis, with a computerized image analyzer or other imaging system, according to accepted biostatistical methods and standards.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: October 25, 1994
    Assignee: The Medical College of Pennsylvania
    Inventors: Olivera T. Markovic, Nenad S. Markovic, Jay Roberts, Charles D. Puglia, Svetomir N. Markovic