Patents by Inventor Netanja Slager

Netanja Slager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING EYE DISORDERS
    Publication number: 20150050328
    Abstract: The present invention relates to compositions and methods for inhibiting loss of a retinal ganglion cell in a subject, comprising non-invasively applying to the surface of the eye of the subject an ophthalmic composition comprising a therapeutically effective amount of at least one siRNA which down regulates expression of a target gene associated with loss of the retinal ganglion cell, thereby inhibiting loss of the retinal ganglion cell in the subject. The methods of the invention also relate to the use of chemically modified siRNA compounds possessing structural motifs which down-regulate the expression of human genes expressed in retinal tissue in the mammalian eye.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 19, 2015
    Inventors: Elena FEINSTEIN, Evgenia ALPERT, Igor METT, Hagar KALINSKI, Amir BAR-ILAN, Igor SPIVAK, Netanja SLAGER
  • Double-stranded oligonucleotide compound for down-regulating the expression of CASP2 gene
    Patent number: 8765931
    Abstract: The present invention relates to compositions and methods for inhibiting loss of a retinal ganglion cell in a subject, comprising non-invasively applying to the surface of the eye of the subject an ophthalmic composition comprising a therapeutically effective amount of at 5 least one siRNA which down regulates expression of a target gene associated with loss of the retinal ganglion cell, thereby inhibiting loss of the retinal ganglion cell in the subject. The methods of the invention also relate to the use of chemically modified siRNA compounds possessing structural motifs which down-regulate the expression of human genes expressed in retinal tissue in the mammalian eye.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: July 1, 2014
    Assignee: Quark Pharmaceuticals, Inc.
    Inventors: Elena Feinstein, Evgenia Alpert, Igor Mett, Amir Bar-Ilan, Igor Spivak, Hagar Kalinski, Netanja Slager, James D. Thompson
  • METHODS FOR TREATING EYE DISORDERS
    Publication number: 20110229557
    Abstract: The present invention relates to compositions and methods for inhibiting loss of a retinal ganglion cell in a subject, comprising non-invasively applying to the surface of the eye of the subject an ophthalmic composition comprising a therapeutically effective amount of at 5 least one siRNA which down regulates expression of a target gene associated with loss of the retinal ganglion cell, thereby inhibiting loss of the retinal ganglion cell in the subject. The methods of the invention also relate to the use of chemically modified siRNA compounds possessing structural motifs which down-regulate the expression of human genes expressed in retinal tissue in the mammalian eye.
    Type: Application
    Filed: October 22, 2009
    Publication date: September 22, 2011
    Inventors: Elena Feinstein, Evgenia Alpert, Igor Mett, Amir Bar-Ilan, Igor Spivak, Hagar Kalinski, Netanja Slager