Patents by Inventor Netta Sela-Paswell

Netta Sela-Paswell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of generating antibodies to metalloenzymes
    Patent number: 10066024
    Abstract: A method of generating an antibody which inhibits a metalloenzyme is disclosed. The method comprises immunizing a subject with: (i) a synthetic zinc mimicry compound having structural and electronic properties similar to a catalytic domain of the metalloenzyme; and (ii) the metalloenzyme, Antibodies generated by this method are also disclosed as well as uses thereof.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: September 4, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irit Sagi, Netta Sela-Paswell, Moran Grossman
  • Antibodies that inhibit metalloproteins
    Patent number: 9217041
    Abstract: An antibody is disclosed which comprises an antigen recognition region which comprises six CDR amino acid sequences selected from the group consisting of SEQ ID NOs: 4-15. Uses thereof are also disclosed.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: December 22, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irit Sagi, Netta Sela-Paswell, Tamar Danon, Raanan Margalit
  • ANTIBODIES THAT INHIBIT METALLOPROTEINS
    Publication number: 20140141014
    Abstract: An antibody is disclosed which comprises an antigen recognition region which comprises six CDR amino acid sequences selected from the group consisting of SEQ ID NOs: 4-15. Uses thereof are also disclosed.
    Type: Application
    Filed: January 30, 2014
    Publication date: May 22, 2014
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Irit SAGI, Netta Sela-Paswell, Tamar Danon, Raanan Margalit
  • Antibodies that inhibit metalloproteins
    Patent number: 8697078
    Abstract: The present application relates to antibodies which recognize [2(2-aminoethylcarbomoyl)-ethoxymethyl]-tris-[2-N-(3-imidazol-1-yl-propyl))-ethoxymethyl]methane, a hapten molecule which closely mimics the local structure and conformation of the reactive zinc site in matrix metalloproteinases. An antibody is disclosed which comprises an antigen recognition region which comprises six CDR amino acid sequences selected from the group consisting of SEQ ID NOs: 4-15. Uses thereof are also disclosed.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: April 15, 2014
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irit Sagi, Netta Sela-Paswell, Tamar Danon, Raanan Margalit
  • METHODS OF GENERATING ANTIBODIES TO METALLOENZYMES
    Publication number: 20130209491
    Abstract: A method of generating an antibody which inhibits a metalloenzyme is disclosed. The method comprises immunizing a subject with: (i) a synthetic zinc mimicry compound having structural and electronic properties similar to a catalytic domain of the metalloenzyme; and (ii) the metalloenzyme, Antibodies generated by this method are also disclosed as well as uses thereof.
    Type: Application
    Filed: October 27, 2011
    Publication date: August 15, 2013
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Irit Sagi, Netta Sela-Paswell, Moran Grossman
  • ANTIBODIES THAT INHIBIT METALLOPROTEINS
    Publication number: 20130039922
    Abstract: The present application relates to antibodies which recognize [2 (2-aminoethylcarbomoyl)-ethoxymethyl]-tris-[2-N-(3-imidazol-1-yl-propyl))-ethoxymethyl]methane, a hapten molecule which closely mimics the local structure and conformation of the reactive zinc site in matrix metalloproteinases. An antibody is disclosed which comprises an antigen recognition region which comprises six CDR amino acid sequences selected from the group consisting of SEQ ID NOs: 4-15. Uses thereof are also disclosed.
    Type: Application
    Filed: January 27, 2011
    Publication date: February 14, 2013
    Applicant: Yeda research and Development Co. Ltd.
    Inventors: Irit Sagi, Netta Sela-Paswell, Tamar Danon, Raanan Margalit