Abstract: Disclosed herein is an automated method for real-time pairing of weapon systems with targets. Databases are populated with inputs which include available weapon systems, targets, and threats. These inputs are entered into a table and the inputs in the table are pre-processed to create formatted data. An optimization engine is executed which analyses the model formulation, selects an algorithm then runs the algorithm. The optimization engine solution is processed into recommended weapon system-target pairings. These recommended weapon system-target pairings are received from the engine then displayed on a user interface. The populating, entering, pre-processing, running, receiving, and displaying are performed in real-time.