Patents by Inventor Neville Crawford

Neville Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iontophoresis, electroporation and combination patches for local drug delivery to body tissues
    Patent number: 6662044
    Abstract: Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined inontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: December 9, 2003
    Assignee: GMP Drug Delivery, Inc.
    Inventors: Neville Crawford, Charles L. Brown, III
  • Iontophoresis, electroporation and combination patches for local drug delivery to body tissues
    Publication number: 20020183685
    Abstract: Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined iontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
    Type: Application
    Filed: July 22, 2002
    Publication date: December 5, 2002
    Applicant: GMP Drug Delivery, Inc.
    Inventors: Neville Crawford, Charles L. Brown
  • Iontophoresis electroporation and combination patches for local drug delivery to body tissues
    Patent number: 6424862
    Abstract: Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined iontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
    Type: Grant
    Filed: February 10, 2000
    Date of Patent: July 23, 2002
    Assignee: GMP Drug Delivery, Inc.
    Inventors: Charles L. Brown, III, Neville Crawford
  • Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
    Patent number: 6219577
    Abstract: Catheter-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the wall tissues of tubular compartments of the living body. One catheter device provides an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only. Another device uses iontophoresis only, electroporation only, or combined iontophoresis and electroporation. In the latter device, the two procedures may be applied sequentially in any order without removing or repositioning the catheter.
    Type: Grant
    Filed: February 19, 1999
    Date of Patent: April 17, 2001
    Assignee: Global Vascular Concepts, Inc.
    Inventors: Charles L. Brown, III, Neville Crawford, Steven Freear
  • Processes for the production of blood products
    Patent number: 4680177
    Abstract: Blood products and derivatives, such as procoagulants--e.g. Factor VIII and rothrombin--plasma proteins, immunoglobulin and complement growth factors and various leucocytes, are obtained from shed blood or its tissue precursor, bone marrow, that has been anticoagulated by the use of a neutral salt that does not bind calcium ions. The preferred anticoagulants are salts containing the divalent ions calcium, magnesium, barium or strontium. Salts of calcium and magnesium are especially preferred because of their relatively lower toxicity, the salt of choice being a magnesium salt, for instance magnesium chloride, because magnesium salts exhibit the required anticoagulating action at levels compatible with retention of normal ionic strength and osmolarity. The toxicity of the neutral salt is eliminated by its removal.
    Type: Grant
    Filed: December 28, 1983
    Date of Patent: July 14, 1987
    Assignees: Trustees of the Garfield Weston Trust for Research into Heart Surgery, The Royal College of Surgeons of England, British Postgraduate Medical Federation
    Inventors: Charles R. W. Gray, Neville Crawford