Patents by Inventor Ángel Cuesta-Martínez

Ángel Cuesta-Martínez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT AND PREVENTION OF GLIOBLASTOMA
    Publication number: 20220008362
    Abstract: The invention relates to the use of a selective ?2 adrenergic receptor antagonist for treating glioma. In particular, the invention relates to the use of an alkanolamine derivative or a pharmaceutically acceptable acid-addition salt thereof for treating a glioblastoma in a patient.
    Type: Application
    Filed: December 12, 2019
    Publication date: January 13, 2022
    Inventors: José María SÁNCHEZ-PUELLES GONZÁLEZ-CARVAJAL, Luisa María BOTELLA CUBELLS, Tania AGUADO SANCHEZ, Ángel CUESTA MARTÍNEZ, Virginia ALBIÑANA DÍAZ, Karina VILLAR GOMEZ-DE LAS HERAS
  • GENERATION OF MULTIFUNCTIONAL AND MULTIVALENT POLYPEPTIDE COMPLEXES WITH COLLAGEN XVIII TRIMERIZATION DOMAIN
    Publication number: 20150139991
    Abstract: The invention relates to the design of trimeric polypeptide complexes using polypeptide structural elements derived from the collagen XVIII protein, and their use in diagnostic and therapeutic systems in vivo and in vitro. The invention also relates to nucleic acids and vectors useful for producing said trimeric complexes.
    Type: Application
    Filed: October 17, 2011
    Publication date: May 21, 2015
    Applicant: LEADARTIS, S.L.
    Inventors: Luis Álvarez Vallina, Ángel Cuesta Martinez, Noelia Sainz Pastor, Laura Sanz Alcober
  • ENGINEERING MULTIFUNCTIONAL AND MULTIVALENT MOLECULES WITH COLLAGEN XV TRIMERIZATION DOMAIN
    Publication number: 20140348826
    Abstract: The invention relates generally to a new trimerization domain useful for developing multifunctional and multivalent complexes. Particularly, the invention relates to the design of trimeric polypeptide complexes using polypeptide structural elements derived from the collagen XV protein, and their use in diagnostic and therapeutic systems in vivo and in vitro. The invention also relates to nucleic acids and vectors useful for producing said trimeric complexes.
    Type: Application
    Filed: August 22, 2011
    Publication date: November 27, 2014
    Applicant: LEADARTIS, S.L.
    Inventors: Luis Álvarez Vallina, Ángel Cuesta-Martínez, Noelia Sainz Pastor, Laura Sanz Alcober
  • Multifunctional and Multivalent Angiogenesis Inhibitors
    Publication number: 20070253952
    Abstract: Multifunctional and multivalent angiogenesis inhibitors are made up of fusion proteins comprising a polypeptide which recognizes and blocks a functionally active region of a molecule involved in the angiogenesis process and a polypeptide comprising an oligomerization domain and functionally active, inhibitor or modulator region of the angiogenesis process, separated by a proteinase-sensitive region. These inhibitors are applicable in treating and preventing pathologies occurring with angiogenesis process, for example cancer, rheumatic arthritis or psoriasis.
    Type: Application
    Filed: October 31, 2005
    Publication date: November 1, 2007
    Applicant: UNIVERSISDAD AUTONOMA DE MADRID
    Inventors: Luis Alvarez Vallina, Victor Sanchez-Arevalo Lobo, Angel Cuesta Martinez, Laura Sanz Alcober, Juan Varga Nunez, Marta Compte Grau