Abstract: Methods and systems for attaching a radiopaque marker to a prosthetic heart valve to indicate a location of a commissure of the prosthetic heart valve are disclosed. As one example, a prosthetic heart valve includes a frame including a plurality of struts forming a plurality of cells of the frame arranged between an inflow end and an outflow end of the frame, a plurality of leaflets arranged within the frame, and at least one commissure comprising an attachment member arranged across a selected cell of the plurality of cells of the frame and commissure tabs of two adjacent leaflets coupled to the attachment member. The valve further includes a radiopaque marker arranged on the attachment member of the commissure within the selected cell.

Abstract: A sheet conveyance device includes a sheet passage, a first sheet stacker, a second sheet stacker, and a sheet feeder. The first sheet stacker has a bottom and a lift. The sheet feeder includes an opening and a feed roller. The sheet conveyance device includes an assist plate supported to be movable between a first and a second position and an urging member. With the first sheet stacker mounted in an apparatus body, the assist plate moves from the first to the second position against the urging force of the urging member to allow passage of a sheet from the first sheet stacker to the sheet feeder. With the first sheet stacker removed from the apparatus body, the assist plate is urged by the urging member to move from the second to the first position to support the sheet conveyed from the second sheet stacker to the sheet feeder.

Abstract: A sheet conveyance device includes a sheet passage, a first sheet stacker, a second sheet stacker, and a sheet feeder. The first sheet stacker has a bottom and a lift. The sheet feeder includes an opening and a feed roller. The sheet conveyance device includes an assist plate supported to be movable between a first and a second position and an urging member. With the first sheet stacker mounted in an apparatus body, the assist plate moves from the first to the second position against the urging force of the urging member to allow passage of a sheet from the first sheet stacker to the sheet feeder. With the first sheet stacker removed from the apparatus body, the assist plate is urged by the urging member to move from the second to the first position to support the sheet conveyed from the second sheet stacker to the sheet feeder.

Abstract: In one embodiment, an irrigated catheter ablation apparatus comprises an elongated body having a distal end, a proximal end, and at least one fluid lumen extending longitudinally therein; and a plurality of segmented ablation electrodes on a distal portion of the elongated body. The electrodes are spaced from the proximal end and from the distal end of the elongated body by electrically nonconductive segments. The electrodes are spaced from each other longitudinally by electrically nonconductive segments. For each electrode that is longitudinally disposed next to one of the nonconductive segments, an edge is formed between an electrode end of the electrode and a nonconductive segment end of the nonconductive segment. A plurality of elution holes are disposed adjacent to the edges. A plurality of ducts establish fluid communication between the elution holes and the fluid lumen.

Abstract: In one embodiment, an irrigated catheter ablation apparatus comprises an elongated body having a distal end, a proximal end, and at least one fluid lumen extending longitudinally therein; and a plurality of segmented ablation electrodes on a distal portion of the elongated body. The electrodes are spaced from the proximal end and from the distal end of the elongated body by electrically nonconductive segments. The electrodes are spaced from each other longitudinally by electrically nonconductive segments. For each electrode that is longitudinally disposed next to one of the nonconductive segments, an edge is formed between an electrode end of the electrode and a nonconductive segment end of the nonconductive segment. A plurality of elution holes are disposed adjacent to the edges. A plurality of ducts establish fluid communication between the elution holes and the fluid lumen.

Abstract: The present invention is directed to a panel of single nucleotide polymorphisms (SNPs) in specific genes that serve as biomarkers for sex-specific prenatal loss of a conceptus or embryo. There is provided herein methods and reagents for assessing the specific SNPs in those genes. The method useful in applying these SNPs in predicting an increased risk of prenatal loss is also disclosed.

Abstract: A system for background image subtraction includes a computing device coupled with a 3D video camera, a processor of the device programmed to receive a video feed from the camera containing images of one or more subject that include depth information. The processor, for an image: segments pixels and corresponding depth information into three different regions including foreground (FG), background (BG), and unclear (UC); categorizes UC pixels as FG or BG using a function that considers the color and background history (BGH) information associated with the UC pixels and the color and BGH information associated with pixels near the UC pixels; examines the pixels marked as FG and applies temporal and spatial filters to smooth boundaries of the FG regions; constructs a new image by overlaying the FG regions on top of a new background; displays a video feed of the new image in a display device; and continually maintains the BGH.

Abstract: A system is disclosed for executing depth image-based rendering of a 3D image by a computer having a processor and that is coupled with one or more color cameras and at least one depth camera. The color cameras and the depth camera are positionable at different arbitrary locations relative to a scene to be rendered. In some examples, the depth camera is a low resolution camera and the color cameras are high resolution. The processor is programmed to propagate depth information from the depth camera to an image plane of each color camera to produce a propagated depth image at each respective color camera, to enhance the propagated depth image at each color camera with the color and propagated depth information thereof to produce corresponding enhanced depth images, and to render a complete, viewable image from one or more enhanced depth images from the color cameras. The processor may be a graphics processing unit.

Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.

Abstract: The present invention is directed to a panel of single nucleotide polymorphisms (SNPs) in specific genes that serve as biomarkers for sex-specific prenatal loss of a conceptus or embryo. There is provided herein methods and reagents for assessing the specific SNPs in those genes. The method useful in applying these SNPs in predicting an increased risk of prenatal loss is also disclosed.

Abstract: A system for background image subtraction includes a computing device coupled with a 3D video camera, a processor of the device programmed to receive a video feed from the camera containing images of one or more subject that include depth information. The processor, for an image: segments pixels and corresponding depth information into three different regions including foreground (FG), background (BG), and unclear (UC); categorizes UC pixels as FG or BG using a function that considers the color and background history (BGH) information associated with the UC pixels and the color and BGH information associated with pixels near the UC pixels; examines the pixels marked as FG and applies temporal and spatial filters to smooth boundaries of the FG regions; constructs a new image by overlaying the FG regions on top of a new background; displays a video feed of the new image in a display device; and continually maintains the BGH.

Abstract: Novel methods for making dosages form comprising a cushioning component. The methods of the present invention provides dosage forms which can be compressed to form compressed dosage forms that are substantially uniform in composition and robust and exhibit reduced friability. The invention also relates to methods for making fast-disintegrating dosage forms.

Abstract: A system is disclosed for executing depth image-based rendering of a 3D image by a computer having a processor and that is coupled with one or more color cameras and at least one depth camera. The color cameras and the depth camera are positionable at different arbitrary locations relative to a scene to be rendered. In some examples, the depth camera is a low resolution camera and the color cameras are high resolution. The processor is programmed to propagate depth information from the depth camera to an image plane of each color camera to produce a propagated depth image at each respective color camera, to enhance the propagated depth image at each color camera with the color and propagated depth information thereof to produce corresponding enhanced depth images, and to render a complete, viewable image from one or more enhanced depth images from the color cameras. The processor may be a graphics processing unit.

Abstract: In one embodiment, an irrigated catheter ablation apparatus comprises an elongated body having a distal end, a proximal end, and at least one fluid lumen extending longitudinally therein; and a plurality of segmented ablation electrodes on a distal portion of the elongated body. The electrodes are spaced from the proximal end and from the distal end of the elongated body by electrically nonconductive segments. The electrodes are spaced from each other longitudinally by electrically nonconductive segments. For each electrode that is longitudinally disposed next to one of the nonconductive segments, an edge is formed between an electrode end of the electrode and a nonconductive segment end of the nonconductive segment. A plurality of elution holes are disposed adjacent to the edges. A plurality of ducts establish fluid communication between the elution holes and the fluid lumen.

Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.

Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.

Abstract: The present invention is directed to a panel of single nucleotide polymorphisms (SNPs) in specific genes that serve as biomarkers for sex-specific childhood leukemia risk. There is provided herein methods and reagents for assessing the specific SNPs in those genes. The method useful in applying these SNPs in predicting an increased risk or a decreased risk for childhood leukemia for males and females is also disclosed.

Abstract: The present invention is directed to a panel of single nucleotide polymorphisms (SNPs) in specific genes that serve as biomarkers for sex-specific prenatal loss of a conceptus or embryo. There is provided herein methods and reagents for assessing the specific SNPs in those genes. The method useful in applying these SNPs in predicting an increased risk of prenatal loss is also disclosed.

Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.

Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.