Abstract: A multilayer metal structure is provided that includes an inner layer of metal materials which are not titanium and outer layers on both sides of the inner layer which are formed by rolling titanium powders. A method for manufacturing the multilayer metal structure is provided that includes preparing titanium powders and metal materials which are not titanium, feeding the titanium powders and the metal materials to a vertical type rolling mill, simultaneously rolling the titanium powders and the metal materials by the rolling mill and forming the multilayer metal structure consisting of an inner layer and outer layers on both sides of the inner layer, and post-forming the multilayer metal structure to increase a packing density.

Abstract: The present invention relates to novel hexa-arm polyethylene glycol (6-arm PEG) and its derivatives. The core of 6-arm PEG derivatives is sorbitol and the end groups can be derivatized into many different reactive functionalities that are useful in conjugating with many different targets. The present invention also provides a biodegradable polymeric hydrogel-forming composition comprising the 6-arm PEG and its derivatives, and methods of using such 6-arm PEG derivatives as surgical or biological implants or sealants.

Abstract: The invention relates to a method for treating symptoms such as stroke comprising administering PEG-hemoglobin (polyethylene glycol-conjugated hemoglobin) solution with specific ability to deliver oxygen to cells under ischemia or hypoxia.