Patents by Inventor Nhuan Phu Nghiem

Nhuan Phu Nghiem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to produce succinic acid from raw hydrolysates
    Patent number: 6743610
    Abstract: A method for producing succinic acid from industrial-grade hydrolysates is provided, comprising supplying an organism that contains mutations for the genes ptsG, pflB, and ldhA, allowing said organism to accumulate biomass, and allowing said organism to metabolize the hydrolysate. Also provided is a bacteria mutant characterized in that it produces succinic acid from substrate contained in industrial-grade hydrolysate in a ratio of between 0.6:1 and 1.3:1 succinic acid to substrate.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: June 1, 2004
    Assignee: The University of Chicago
    Inventors: Mark I. Donnelly, Cynthia Y. Sanville-Millard, Nhuan Phu Nghiem
  • Method to produce succinic acid from raw hydrolysates
    Publication number: 20030017559
    Abstract: A method for producing succinic acid from industrial-grade hydrolysates is provided, comprising supplying an organism that contains mutations for the genes ptsG, pflB, and ldhA, allowing said organism to accumulate biomass, and allowing said organism to metabolize the hydrolysate. Also provided is a bacteria mutant characterized in that it produces succinic acid from substrate contained in industrial-grade hydrolysate in a ratio of between 0.6:1 and 1.3:1 succinic acid to substrate.
    Type: Application
    Filed: March 30, 2001
    Publication date: January 23, 2003
    Inventors: Mark I. Donnelly, Cynthia Y. Sanville-Millard, Nhuan Phu Nghiem
  • Method for the production of dicarboxylic acids
    Patent number: 5869301
    Abstract: The present invention is an economical fermentation method for the production of carboxylic acids comprising the steps of a) inoculating a medium having a carbon source with a carboxylic acid-producing organism; b) incubating the carboxylic acid-producing organism in an aerobic atmosphere to promote rapid growth of the organism thereby increasing the biomass of the organism; c) controllably releasing oxygen to maintain the aerobic atmosphere; d) controllably feeding the organism having increased biomass with a solution containing the carbon source to maintain the concentration of the carbon source within the medium of about 0.5 g/L up to about 1 g/L; e) depriving the aerobic atmosphere of oxygen to produce an anaerobic atmosphere to cause the organism to undergo anaerobic metabolism; f) controllably feeding the organism having increased biomass a solution containing the carbon source to maintain the concentration of the carbon source within the medium of .gtoreq.
    Type: Grant
    Filed: January 31, 1997
    Date of Patent: February 9, 1999
    Assignee: Lockhead Martin Energy Research Corporation
    Inventors: Nhuan Phu Nghiem, Mark Donnelly, Cynthia S. Millard, Lucy Stols