Abstract: Provided is an anesthetic composition for locally administering a local anesthetic agent to a subject in need thereof. The anesthetic composition has a lipid based complex prepared by hydrating a lipid cake containing a local anesthetic agent and a lipid mixture with an aqueous buffer solution at a pH higher than 5.5. Also provided is a method to prepare an anesthetic composition using a simpler and more robust for large-scale manufacture and for providing a high molar ratio of local anesthetic agent to phospholipid content as compared to the prior art. This anesthetic composition has a prolonged duration of efficacy adapted to drug delivery.

Abstract: Examples of an integrated circuit with gate cut features and a method for forming the integrated circuit are provided herein. In some examples, a workpiece is received that includes a substrate and a plurality of fins extending from the substrate. A first layer is formed on a side surface of each of the plurality of fins such that a trench bounded by the first layer extends between the plurality of fins. A cut feature is formed in the trench. A first gate structure is formed on a first fin of the plurality of fins, and a second gate structure is formed on a second fin of the plurality of fins such that the cut feature is disposed between the first gate structure and the second gate structure.

Abstract: A wavelength conversion element including a substrate, a blocking wall structure layer, and a wavelength conversion layer is provided. The blocking wall structure layer is disposed on a surface of the substrate and defines multiple microgrooves. Reflectivity of the blocking wall structure layer is in a range of 1% to 99%. The wavelength conversion layer is disposed in the microgrooves and includes multiple wavelength conversion particles. A height of the blocking wall structure layer along a normal direction of the surface of the substrate is greater than a height of the wavelength conversion layer along the normal direction of the surface of the substrate. A backlight module adopting the wavelength conversion element is also provided.

Abstract: A hammer structure includes a hammer body, at least one hitting block, a compression spring, and a shaft. The hammer body has a radial through hole. The hitting block includes a mounting portion having an accommodating hole. The compression spring is accommodated in the accommodating hole. The shaft is inserted through the compression spring so that it can be elastically extended and retracted via the compression spring. The mounting portion of the hitting block is screwed to the end of the hammer body. The shaft counteracts an elastic force of the compression spring to be partially engaged in the radial through hole. The hammer structure can prevent the hitting block screwed to a mounting groove of the hammer body from being loosened due to strong impact and vibration in the hitting process, so as to fix the hitting block and avoid damage effectively.

Abstract: A quantum dot composition includes a matrix resin, a quantum dot phosphor, and a polysilane polymer. The matrix resin includes epoxy-fluorene copolymer acrylic resin represented by Formula 1: Formula 1. In Formula 1, R1 and R4 each is independently hydrogen or a C1-C12 long alkyl carbon chain. R2 and R3 each is independently a is an integer from 1 to 10, and b and c each is independently an integer from 0 to 10. X is 0.1 to 0.9. A color conversion film including the quantum dot composition and a backlight module using the color conversion film are also provided.

Abstract: A quantum dot composition includes a matrix resin, a quantum dot phosphor, and a polysilane polymer. The matrix resin includes epoxy-fluorene copolymer acrylic resin represented by Formula 1: Formula 1. In Formula 1, R1 and R4 each is independently hydrogen or a C1-C12 long alkyl carbon chain. R2 and R3 each is independently a is an integer from 1 to 10, and b and c each is independently an integer from 0 to 10. X is 0.1 to 0.9. A color conversion film including the quantum dot composition and a backlight module using the color conversion film are also provided.

Abstract: The disclosure relates to compositions and methods for treatment of diseases associated with aberrant lysosomal function, such as fronto-temporal dementia (FTD). The disclosure also provides expression constructs comprising a transgene encoding progranulin or a portion thereof. The disclosure provides methods of treating FTD by administering such expression constructs to a subject in need thereof.

Abstract: Disclosed herein is a method against influenza A viral infection, including administering to a subject in need thereof tryptophan and arginine.

Abstract: A method and a device for dynamically switching a keyboard background are disclosed. The method comprises: monitoring a parameter associated with switching the keyboard background and determining whether to trigger a dynamic switching of the keyboard background (S1); and when it is determined to trigger a dynamic switching of the keyboard background, obtaining an unused picture corresponding to a designated view from a respective background package and replacing a picture being currently used in the designated view with said unused picture (S2). Monitoring the associated parameters allows switching the background between predetermined pictures and hence provides a better personalized experience.

Abstract: The present invention relates to a use of alpha-(8-quinolinyloxy) mono-substituted phthalocyanine zinc for the treatment of psoriasis. The use is suitable for various type of psoriasis by utilizing photodynamic therapy. The photosensitizer is used to treat psoriasis by utilizing laser wave length of 670 nm, with high light sensitivity, fast photobleaching, short time needed in protection from light, and avoiding potential toxic and side-effect of photochemistry therapy by using ultraviolet irradiation. The preparation used in the use of ?-(8-quinolinyloxy) mono-substituted phthalocyanine zinc for the treatment of psoriasis includes solution, cream, nanomicelle, microsphere etc, and mode of administration can be systemic or topical administration. The practicability of treating psoriasis by photodynamic therapy has been validated on cell and animal model. The use achieves perfect effect.

Abstract: The present invention relates to a use of alpha-(8-quinolinyloxy) mono-substituted phthalocyanine zinc for the treatment of psoriasis. The use is suitable for various type of psoriasis by utilizing photodynamic therapy. The photosensitizer is used to treat psoriasis by utilizing laser wave length of 670 nm, with high light sensitivity, fast photobleaching, short time needed in protection from light, and avoiding potential toxic and side-effect of photochemistry therapy by using ultraviolet irradiation. The preparation used in the use of ?-(8-quinolinyloxy) mono-substituted phthalocyanine zinc for the treatment of psoriasis includes solution, cream, nanomicelle, microsphere etc, and mode of administration can be systemic or topical administration. The practicability of treating psoriasis by photodynamic therapy has been validated on cell and animal model. The use achieves perfect effect.

Abstract: The present invention aims at converting factor IX into a molecule with enhanced activity which provides an alternative for replacement therapy and gene therapy for hemophilia B. Using recombinant techniques, factor IX with replacement at positions 86, 277, and 338 exhibits better clotting activity than recombinant wild type factor IX.

Abstract: The present invention aims at converting factor IX into a molecule with enhanced activity which provides an alternative for replacement therapy and gene therapy for hemophilia B. Using recombinant techniques, factor IX having substitution of amino acid residue of SEQ ID NO: 7 at amino acid position selected from the group consisting of 86, 277, and 338 (exclude the circumstance of a single substitution at amino acid position 338) exhibits better clotting activity than recombinant wild type factor IX.

Abstract: The present invention aims at converting factor IX into a molecule with enhanced activity which provides an alternative for replacement therapy and gene therapy for hemophilia B. Using recombinant techniques, factor IX with replacement at positions 86, 277, and 338 exhibits better clotting activity than recombinant wild type factor IX.

Abstract: A screwdriver handle includes a body having an angled hollow grip at the rear end and a chuck at the front end for the mounting of an adapter shaft to hold a screwdriver tip in axial alignment with the body, a rack insertable into the inside of the hollow grip and having two rows of vertically spaced C-shaped clamping plates for accommodating screwdriver tips and an extension rod holder groove for accommodating an extension rod, and a cap capped on the bottom end of the grip to close the grip and to hold down the rack firmly inside the grip

Abstract: An integrated module of antenna and connector has an insulative housing receiving a plurality of conductive terminals therein, a metal shell shielding the insulative housing, and a coupling device assembled on the metal shell. The metal shell is grounded and defines a slot with a particular shape. A feed-in terminal is provided on a side of the slot and includes a soldering portion and a contact portion. The soldering portion of the feed-in terminal connects with a circuit board. The coupling device contacts the contact portion of the feed-in terminal, feeding in high-frequency voltage which forms voltage difference relative to a plane of the slot. A resonant electromagnetic field is produced in the slot for working as an antenna for electromagnetic wave radiation. Thus, functions of an antenna and a connector are combined, reducing the occupied space and decreasing the cost.

Abstract: The present invention aims at converting factor IX into a molecule with enhanced activity which provides an alternative for replacement therapy and gene therapy for hemophilia B. Using recombinant techniques, factor IX with replacement at positions 86, 277, and 338 exhibits better clotting activity than recombinant wild type factor IX.

Abstract: An integrated module of antenna and connector has an insulative housing receiving a plurality of conductive terminals therein, a metal shell shielding the insulative housing, and a coupling device assembled on the metal shell. The metal shell is grounded and defines a slot with a particular shape. A feed-in terminal is provided on a side of the slot and includes a soldering portion and a contact portion. The soldering portion of the feed-in terminal connects with a circuit board. The coupling device contacts the contact portion of the feed-in terminal, feeding in high-frequency voltage which forms voltage difference relative to a plane of the slot. A resonant electromagnetic field is produced in the slot for working as an antenna for electromagnetic wave radiation. Thus, functions of an antenna and a connector are combined, reducing the occupied space and decreasing the cost.

Abstract: A multiband frequency selective filter is assembled on a housing or an antenna module of a small portable device. The multiband frequency selective filter comprises at least two overlapped substrates. Each substrate includes a dielectric base and a conductive layer. The conductive layers respectively form unit cells. The unit cells are arrayed periodically or non-periodically. Appropriate shape and arrangement of the unit cells and overlapping of the substrates, forms a three-dimensional resonant array of inductance and capacitance in direction of a plane and height of the unit cells, thereby evidently lessening resonant wave length of electromagnetic wave and achieving miniature of unit cells of FSS.