Patents by Inventor Ni Ming Hong

Ni Ming Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
    Patent number: 7589099
    Abstract: Compounds of Formula (I) are described: in which the R1 group is as defined in the specification and includes the condensation of 7-t-butoxyiminomethylcamptothecin in position 20 with a cyclopeptide containing the RGD sequence. Said compounds are endowed both with high affinity for integrin receptors ?v?3 and ?v?5 and with selective cytotoxic activity on human tumour cell lines at micromolar concentrations.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: September 15, 2009
    Assignee: Sigma-Tau Industrie Farmaceutiche Reunite S.p.A.
    Inventors: Claudio Pisano, Giuseppe Giannini, Loredana Vesci, Domenico Alloatti, Sergio Penco, Alma Dal Pozzo, Ni Ming Hong, Sabrina Dallavalle, Lucio Merlini, Maria Ornella Tinti, Franco Zunino