Patents by Inventor Niall Hynes

Niall Hynes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12110546
    Abstract: The present application relates to tertiary amine substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: October 8, 2024
    Assignee: Illumina Cambridge Limited
    Inventors: Nikolai Nikolaevich Romanov, Patrick McCauley, Niall Hynes
  • Publication number: 20240271209
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: April 9, 2024
    Publication date: August 15, 2024
    Inventors: Nikolai Nikolaevich Romanov, Michael Callingham, Carole Anastasi, Patrick McCauley, Niall Hynes, Natasha Crake, Xiaolin Wu, Xiaohai Liu
  • Publication number: 20240264182
    Abstract: Extended duration cell analysis is provided via a device, comprising: a chamber configured to accept: a sample carrier, that includes a plurality of wells having electrodes in electrical communication with an impedance meter; and a cartridge, including a compound and at least one delivery port for the compound; a camera configured to capture images of a cell culture in each well via associated windows in the wells when the sample carrier is positioned at a first location; a fluid handler, in communication with the sample carrier and the cartridge when the sample carrier is positioned at a second location, configured to deliver the compound from the cartridge to a given well based on an impedance measurement of a sample in the given well; and a motion stage configured to move the sample carrier between the first location and the second location.
    Type: Application
    Filed: February 2, 2024
    Publication date: August 8, 2024
    Inventors: Brady Robert Paradis, James Niall Hynes, Maria Natalia Romero Filardo, Jason Dell'Arciprete
  • Patent number: 11981964
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: May 14, 2024
    Assignee: Illumina Cambridge Limited
    Inventors: Nikolai Nikolaevich Romanov, Michael Callingham, Carole Anastasi, Patrick Mccauley, Niall Hynes, Natasha Crake, Xiaolin Wu, Xiaohai Liu
  • Patent number: 11858923
    Abstract: The present application relates to secondary amine-substituted coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: January 2, 2024
    Assignee: Illumina Cambridge Limited
    Inventors: Nikolai Nikolaevich Romanov, Patrick McCauley, Carole Anastasi, Xiaolin Wu, Niall Hynes
  • Publication number: 20230313292
    Abstract: The present application relates to chromenoquinoline dyes and their uses as fluorescent labels. For example, these dyes may be used to label nucleotides for nucleic acid sequencing.
    Type: Application
    Filed: March 27, 2023
    Publication date: October 5, 2023
    Inventors: Michael Callingham, Niall Hynes, Nikolai Nikolaevich Romanov
  • Publication number: 20230128888
    Abstract: Disclosed herein are methods and systems for evaluating the bioenergetic poise and bioenergetic capacity of living cells in a single assay.
    Type: Application
    Filed: October 11, 2022
    Publication date: April 27, 2023
    Inventors: Maria Natalia Romero Filardo, James Niall Hynes
  • Publication number: 20230025669
    Abstract: The present application relates to secondary amine-substituted coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: July 1, 2022
    Publication date: January 26, 2023
    Inventors: Nikolai Nikolaevich ROMANOV, Patrick MCCAULEY, Carole ANASTASI, Xiaolin WU, Niall HYNES
  • Patent number: 11390619
    Abstract: The present application relates to secondary amine-substituted coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: July 19, 2022
    Assignee: Illumina Cambridge Limited
    Inventors: Nikolai Nikolaevich Romanov, Patrick McCauley, Carole Anastasi, Xiaolin Wu, Niall Hynes
  • Publication number: 20220033900
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: July 26, 2021
    Publication date: February 3, 2022
    Inventors: Nikolai Nikolaevich ROMANOV, Michael CALLINGHAM, Carole ANASTASI, Patrick MCCAULEY, Niall HYNES, Natasha CRAKE, Xiaolin WU, Xiaohai LIU
  • Publication number: 20210188832
    Abstract: The present application relates to secondary amine-substituted coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: October 16, 2018
    Publication date: June 24, 2021
    Inventors: Nikolai Nikolaevich ROMANOV, Patrick MCCAULEY, Carole ANASTASI, Xiaolin WU, Niall HYNES
  • Publication number: 20200277670
    Abstract: The present application relates to tertiary amine substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: February 28, 2020
    Publication date: September 3, 2020
    Inventors: Nikolai Nikolaevich Romanov, Patrick McCauley, Niall Hynes