Patents by Inventor Nian-Han MA

Nian-Han MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11427870
    Abstract: A method for estimating a risk for a subject suffering from encapsulating peritoneal sclerosis is provided, including measuring an expression level of at least one microRNA from a sample of the subject, and the microRNA is selected from miR-17, miR-100, miR-155, miR-202, miR-422a, and miR-483; comparing the expression level of the microRNA in the sample to that of a same miRNA of a control, when the expression level of miRNA in the sample is lower than that of the control, the subject is estimated having the risk of encapsulating peritoneal sclerosis. A kit for estimating a risk for a subject suffering from encapsulating peritoneal sclerosis is also provided, including at least one agent for identifying the at least one microRNA as above mentioned from the sample of the subject.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: August 30, 2022
    Assignee: National Central University
    Inventors: Nian-Han Ma, Chiu-Chin Huang, Jin-Bor Chen, Chin-Chung Tseng, I-Kuan Wang, Chien-Lung Chen, An-Lun Li
  • Publication number: 20210388440
    Abstract: A method for estimating a risk for a subject suffering from encapsulating peritoneal sclerosis is provided, including measuring an expression level of at least one microRNA from a sample of the subject, and the microRNA is selected from miR-17, miR-100, miR-155, miR-202, miR-422a, and miR-483; comparing the expression level of the microRNA in the sample to that of a same miRNA of a control, when the expression level of miRNA in the sample is lower than that of the control, the subject is estimated having the risk of encapsulating peritoneal sclerosis. A kit for estimating a risk for a subject suffering from encapsulating peritoneal sclerosis is also provided, including at least one agent for identifying the at least one microRNA as above mentioned from the sample of the subject.
    Type: Application
    Filed: July 9, 2020
    Publication date: December 16, 2021
    Applicant: National Central University
    Inventors: Nian-Han Ma, Chiu-Chin Huang, Jin-Bor Chen, Chin-Chung Tseng, I-Kuan Wang, Chien-Lung Chen, An-Lun Li
  • Patent number: 11098371
    Abstract: A kit for detecting urothelial carcinoma is provided. The kit includes at least one primer or probe for detecting one or more miRNAs, and the one or more miRNAs are selected from the group consisting of miR-19b-1, miR-636, miR-150, miR-155, miR-183, miR-378, miR-210, miR-487, and combinations thereof. A method for detecting urothelial carcinoma is also provided. The method includes detecting the expression level(s) of one or more miRNAs in a sample of a subject, and the one or more miRNAs are selected from the group consisting of miR-19b-1, miR-636, miR-150, miR-155, miR-183, miR-378, miR-210, miR-487, and combinations thereof.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: August 24, 2021
    Assignees: NATIONAL CENTRAL UNIVERSITY, DELTA ELECTRONICS. INC.
    Inventors: Nian-Han Ma, Chien-Lung Chen, Chen-Huan Lin, An-Lun Li, Chiu-Chin Huang, Chao-Hsiang Chang
  • Patent number: 10738363
    Abstract: The present invention provides an analyzer for predicting a prognosis of cancer radiotherapy, including a detection device and an arithmetic device. In a specimen, expression levels of a plurality of microRNAs (miRNAs) can be detected by the detection device. The miRNAs includes hsa-miR-130a-3p, hsa-miR-215-5p, hsa-miR-29a-3p, hsa-let-7b-5p, hsa-miR-19b-3p, hsa-miR-374a-5p and hsa-miR-148a-3p. The expression levels of miRNAs can be analyzed by the arithmetic device using logistic regression, and the analyzed values can be used to determine that the prognosis of cancer radiotherapy is poor or good.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: August 11, 2020
    Assignees: NATIONAL CENTRAL UNIVERSITY
    Inventors: Nian-Han Ma, Tao-Sheng Chung, An-Lun Li, Yao-Ning Chan, Chien-Lung Chen
  • Publication number: 20200248268
    Abstract: A method for estimating a risk for a subject suffering from an urothelial carcinoma is provided, including measuring an expression level of at least one miRNA in a sample of the subject, and the miRNA is selected from miR-1274, miR-19a, miR-30, and miR-708; and comparing the expression level of the same miRNA in the sample to that of a control for estimating whether the subject has the risk of suffering from the urothelial carcinoma or not. A kit for estimating a risk for a subject suffering from an urothelial carcinoma is also provided, including at least one reagent for detecting an expression level of at least one miRNA as above mentioned in a sample of the subject.
    Type: Application
    Filed: October 21, 2019
    Publication date: August 6, 2020
    Inventors: Nian-Han Ma, Chiu-Chin Huang, Chao-Hsiang Chang, Chien-Lung Chen, An-Lun Li
  • Publication number: 20200149113
    Abstract: A kit for detecting urothelial carcinoma is provided. The kit includes at least one primer or probe for detecting one or more miRNAs, and the one or more miRNAs are selected from the group consisting of miR-19b-1, miR-636, miR-150, miR-155, miR-183, miR-378, miR-210, miR-487, and combinations thereof. A method for detecting urothelial carcinoma is also provided. The method includes detecting the expression level(s) of one or more miRNAs in a sample of a subject, and the one or more miRNAs are selected from the group consisting of miR-19b-1, miR-636, miR-150, miR-155, miR-183, miR-378, miR-210, miR-487, and combinations thereof.
    Type: Application
    Filed: July 2, 2019
    Publication date: May 14, 2020
    Inventors: Nian-Han MA, Chien-Lung CHEN, Chen-Huan LIN, An-Lun LI, Chiu-Chin HUANG, Chao-Hsiang CHANG
  • Publication number: 20180057891
    Abstract: The present invention provides an analyzer for predicting a prognosis of cancer radiotherapy, including a detection device and an arithmetic device. In a specimen, expression levels of a plurality of microRNAs (miRNAs) can be detected by the detection device. The miRNAs includes hsa-miR-130a-3p, hsa-miR-215-5p, hsa-miR-29a-3p, hsa-let-7b-5p, hsa-miR-19b-3p, hsa-miR-374a-5p and hsa-miR-148a-3p. The expression levels of miRNAs can be analyzed by the arithmetic device using logistic regression, and the analyzed values can be used to determine that the prognosis of cancer radiotherapy is poor or good.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 1, 2018
    Inventors: Nian-Han MA, Tao-Sheng CHUNG, An-Lun LI, Yao-Ning CHAN, Chien-Lung CHEN