Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: The present invention relates to a negative electrode material comprising a hydrogen storage alloy and a coating layer on a surface of the hydrogen storage alloy. Based on the mass of the negative electrode active material, a content of the coating layer is no less than 2 wt %. The coating layer comprises a component shown by a general formula LnFx, wherein Ln is one element selected from the group consisting of La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Y, and Sc. The present invention also relates to a preparation method for the above-described negative electrode material. The present invention also relates to a nickel-metal hydride secondary battery using this negative electrode material.

Abstract: This application discloses data transmission that includes: dividing to-be-transmitted content into a plurality of data units at a session layer; transmitting the data units to the target terminal device by using a first transmission channel as a responsible channel of the to-be-transmitted content; distributing, by the session layer in a case that the session layer switches the responsible channel of the to-be-transmitted content from the first transmission channel to a second transmission channel with a different transmission protocol, the data units to the second transmission channel; and transmitting the data units distributed by the session layer to the target terminal device through the second transmission channel. In data transmission in this application, the session layer controls switching of the channels and distribution of the data units, so that the transmission sequence is free from constraints of protocols and the degree of freedom in data transmission is increased.

Abstract: The invention provides a beam optical axis self-stabilizing device and method based on reflection mechanical modulation. The device includes a polarized beam splitter, a quarter-wave plate, a structural reflecting element, and a driving source. The quarter-wave plate is located at an output end of the polarized beam splitter. The reflecting element is located at a side of the quarter-wave plate away from the polarized beam splitter. The driving source drives the structural reflecting element to rotate at a uniform speed with an optical axis as an axis. Incident light passes through the polarized beam splitter to obtain split light. The split light passes through the quarter-wave plate to enter the structural reflecting element. The structural reflecting element rotates so that the phase of reflected light varies with time. The reflected light is modulated by the quarter-wave plate and emitted through the polarized beam splitter, and a target beam is obtained.

Abstract: The invention disclosed an intelligent dehumidification device for a hot air circulation baking system, which internally includes a compressor, a condenser, a throttle valve, an evaporator, a total heat exchanger, a controller, a heat dissipation fan, a liquid level sensor, a temperature and humidity sensor, an axial flow fan, a drain solenoid valve, a condensate collecting box and a temperature sensor and externally includes a dehumidification air inlet, a dehumidification air outlet, a fresh air inlet, a heat dissipation air outlet and a condensate discharge port.

Abstract: The invention disclosed an intelligent dehumidification device for a hot air circulation baking system, which internally includes a compressor, a condenser, a throttle valve, an evaporator, a total heat exchanger, a controller, a heat dissipation fan, a liquid level sensor, a temperature and humidity sensor, an axial flow fan, a drain solenoid valve, a condensate collecting box and a temperature sensor and externally includes a dehumidification air inlet, a dehumidification air outlet, a fresh air inlet, a heat dissipation air outlet and a condensate discharge port.

Abstract: A nozzle assembly includes a support member, a first tube, a second tube, and a baffling member. The support member defines a receiving hole and an opening communicating with the receiving hole. The first tube extends through the opening and defines a first space communicating with the receiving hole. The second tube is retained within the receiving hole and defines a second space communicating with the receiving hole. The baffling member is securely connected to an end of the second tube that is retained within the receiving hole. The baffling member forms a plurality of gaps for directing the airflow from the first space.

Abstract: A nozzle assembly includes a support member, a first tube, a second tube, and a baffling member. The support member defines a receiving hole and an opening communicating with the receiving hole. The first tube extends through the opening and defines a first space communicating with the receiving hole. The second tube is retained within the receiving hole and defines a second space communicating with the receiving hole. The baffling member is securely connected to an end of the second tube that is retained within the receiving hole. The baffling member forms a plurality of gaps for directing the airflow from the first space.

Abstract: An energy harvesting device (FIG. 1) and a method of using the energy harvesting device to generate an electrical charge are described. The energy harvesting device comprises a mass (2) and at least two tethers (4, 6, S and 10), at least one of which comprises a piezoelectric material that is mechanically stressable upon deflection of the at least two tethers. Each of the tethers comprises a first end (12) coupled to the mass (2) and a second end (14) copied to a reference structure (16), and the tethers are arranged about the mass such that the mass is moveable within a straight line path relative to the reference. The movement of the mass causes the deflection of the tethers, resulting in the generation of an electric charge. The device is preferably operable at the microscale.

Abstract: An energy harvesting device and a method of using the energy harvesting device to generate an electrical charge are described. The energy harvesting device comprises a mass and at least two tethers, at least one of which comprises a piezoelectric material that is mechanically stressable upon deflection of the at least two tethers. Each of the tethers comprises a first end coupled to the mass and a second end coupled to a reference structure, and the tethers are arranged about the mass such that the mass is moveable within a straightline path relative to the reference. The movement of the mass causes the deflection of the tethers, resulting in the generation of an electric charge. The device is preferably operable at the microscale.

Abstract: The present invention provides transgenic mice and nucleic acid constructs and methods for creating them. The transgenic mice are generated preferably by electroporation-mediated transfection of a nucleic acid construct into the testes of a sterile spermatogenesis-deficient male mouse. The construct includes DNA encoding a spermatogenesis rescue factor resulting in rescue of spermatogenesis while contemporaneously transferring a nucleic acid of interest for expression in the transgenic mouse so that progeny sired by the transgenic mouse also harbor the transgene. Certain embodiments of the invention also utilize (a) the salmonid derived Sleeping Beauty transposition system to augment genomic integration of the transgene and/or (b) the Cre/loxP recombination system for excision from sired progeny of the DNA responsible for spermatogenesis rescue.

Abstract: This invention relates to a new synthetic process for the preparation of anti-tumor agent Etoposide (VP16-213). the process, which has shorten reaction route, simple procedure, high yield and low materials cost, therefore facilitates the commercial manufacture of etoposide.