Patents by Inventor Niccolo PENGO

Niccolo PENGO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES AGAINST TDP-43 AND METHODS OF USING THE SAME
    Publication number: 20240150449
    Abstract: The present invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to the pathological form of TDP-43, which characterizes various TDP-43 proteinopathies. The antibodies, and antigen binding fragments thereof, decrease TDP-43 aggregation observed under pathological conditions. The invention also relates to nucleic acids that encode, and to cells that express such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies and antibody fragments in the diagnosis, treatment and prevention of TDP-43 proteinopathies.
    Type: Application
    Filed: March 10, 2022
    Publication date: May 9, 2024
    Inventors: Dimitri BIELI, Natascha WUILLEMIN, Niccolo PENGO, Tiziana Maria SONATI, Pierre DE ROSSI, Magdalini POLYMENIDOU, Marc EMMENEGGER, Adriano AGUZZI
  • ANTIBODIES AGAINST KLK5
    Publication number: 20230075753
    Abstract: The present invention relates to antibodies which bind and inhibit KLK5 and methods of using the same to treat diseases caused by KLK5 imbalance. In particular, the present invention relates to inhibitory antibodies binding KLK5 and their use in the treatment of Netherton disease, atopic dermatitis and cancer.
    Type: Application
    Filed: February 1, 2021
    Publication date: March 9, 2023
    Inventors: Neesha DEDI, Peter Charles ELLIOTT, Seppe Frans Roman LEYSEN, Sean MASON, David James MCMILLAN, Gillian Claire NESS, Niccolo PENGO, Martin Anthony REDHEAD, Alison TURNER, Kerry Louise TYSON
  • ANTIBODIES AGAINST KLK5
    Publication number: 20230070261
    Abstract: The present invention relates to antibodies which bind and inhibit KLK5 and methods of using the same to treat diseases caused by KLK5 imbalance. In particular, the present invention relates to inhibitory anti-KLK5 antibodies and their use in the treatment of Netherton disease, atopic dermatitis and cancer.
    Type: Application
    Filed: February 1, 2021
    Publication date: March 9, 2023
    Inventors: Neesha DEDI, Peter Charles ELLIOTT, Seppe Frans Roman LEYSEN, Sean MASON, David James MCMILLAN, Gillian Claire NESS, Niccolo PENGO, Martin Anthony REDHEAD, Alison TURNER, Kerry Louise TYSON