Patents by Inventor Nicholaos K. Harakas

Nicholaos K. Harakas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Large scale production of plasminogen activator from normal human colon cells
    Patent number: 5132214
    Abstract: Plasminogen activators (PA) are obtained from cultured normal human colon cells which are adaptable to large scale production. A purified tissue PA (t-PA) is obtained from CCD-18Co normal human colon fibroblast cells which shows chemical differences from Bowes melanoma t-PA.
    Type: Grant
    Filed: April 9, 1986
    Date of Patent: July 21, 1992
    Assignee: Monsanto Company
    Inventors: Joseph Feder, Nicholaos K. Harakas, Jon P. Schaumann, Daniel T. Connolly, Arthur J. Wittwer
  • Monoclonal antibody specific for human colon fibroblast-derived t-PA
    Patent number: 4891312
    Abstract: A monoclonal antibody is disclosed which is specific for human colon fibroblast-derived tissue plasminogen activator (t-PA), and which is useful for immunoaffinity chromatography purification of t-PA and determination of t-PA in a biological sample.
    Type: Grant
    Filed: January 6, 1989
    Date of Patent: January 2, 1990
    Assignee: Monsanto Company
    Inventors: Jon P. Schaumann, Jitka V. Olander, Nicholaos K. Harakas, Joseph Feder
  • Monoclonal antibody specific for human colon fibroblast-derived t-PA
    Patent number: 4833085
    Abstract: A monoclonal antibody is disclosed which is specific for human colon fibroblast-derived tissue plasminogen activator (t-PA), and which is useful for immunoaffinity chromatography purification of t-PA and determination of t-PA in a biological sample.
    Type: Grant
    Filed: August 13, 1986
    Date of Patent: May 23, 1989
    Assignee: Monsanto Company
    Inventors: Jon P. Schaumann, Jitka V. Olander, Nicholaos K. Harakas, Joseph Feder