Patents by Inventor NICHOLAS A. BE

NICHOLAS A. BE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160136255
    Abstract: Vaccines comprising Mycobacterium tuberculosis (M. tuberculosis) PknD sensor polypeptides, compositions, kits, and methods of use for treating central nervous system tuberculosis are disclosed. More specifically, the disclosure provides a method for treating or preventing central nervous system (CNS) tuberculosis (TB) in a subject, the method comprises administering to the subject a therapeutically effective amount of a vaccine comprising an M tuberculosis PknD sensor polypeptide, or an immunogenic fragment for inhibiting or preventing M tuberculosis bacterial invasion of brain microvascular endothelia.
    Type: Application
    Filed: June 6, 2014
    Publication date: May 19, 2016
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: SANJAY K. JAIN, CIARAN SKERRY, NICHOLAS A. BE