Abstract: Provided herein are systems, devices, and methods for performing optical multianalyte detection in a sample, such as a human blood sample. The system processes sample in a single-use support pack that holds the blood sample and contains pipette tips, buffers, reagent preparation wells and a monolayer. Sample is transferred from the sample pack to a single-use disc consumable that contains microwells pre-filled with dried chemistries, plasma separation features, and a hematocrit channel. The instrument comprises a cell imager, an absorbance module comprising a spectrophotometer, a fluorescent laser scanning module, and a camera. The system uses only a small amount of blood from a single heparinized sample, to simultaneously provide results for a full panel of routine blood tests spanning elecochemistry, clinical chemistry, hematology, immunoassays and combinations thereof.

Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: Embodiments of the present invention provide concepts for camera modules including multiple apertures but only one image sensor for sensing light received via the multiple apertures. In particular, embodiments may provide a camera module including electrically controllable reflective components able to switch between reflective and transmissive states such that light from the apertures may be directed towards the single image sensor or not.

Abstract: A network access point enclosure is configured to house a splice tray that is configured to pivot to provide increased access to opposite sides of the splice tray during assembly. The enclosure includes a base, a cover configured to be sealingly coupled with the base to form a housing, and a splice tray configured to be pivotally coupled with the base. The splice tray is configured to be pivoted between a first orientation relative to the base and a second orientation relative to the base. The splice tray is configured to form a larger angle relative to the base in the first orientation than in the second orientation, and the splice tray is configured to provide increased access to a front side of the splice tray and a rear side of the splice tray in the first orientation than in the second orientation.

Abstract: Methods and systems are described for determining a video resource allocation for outputting content via a display. The video resource allocation may be determined based on priorization data that priorities different areas of the content. A greater portion of resources for outputting the content may be allocated to different areas of the content based on the priorization of data.

Abstract: An example operation may include one or more of downloading a container image of a web service from a data store, wherein the web service is configured to be self-hosted, deploying a self-hosted copy of the web service within a container runtime of a local device based on execution of the downloaded container image, and modifying a domain name system (DNS) to include a mapping of the web service to a local network address of the self-hosted copy of the web service deployed in the container runtime.

Abstract: According to an embodiment, a method includes receiving a pre-trained neural network and removing a last feed forward layer from the pre-trained neural network. The method further includes appending the pre-trained neural network with a secondary last feed forward layer, a quantum circuit, and another feed forward layer, and determining a number of measurements from the quantum circuit based on a plurality of qubits and a plurality of parameters output from the secondary last feed forward layer. The method further includes using a cross-entropy loss function to determine the difference between a probability distribution, output from the last feed forward layer, for a number of variables and a true value for each of the number of variables. Lastly, the method includes updating one or more weights associated with the number of variables in the pre-trained neural network through an optimizer.

Abstract: According to an embodiment, a method includes removing a last feed forward layer from a pre-trained neural network. The method further includes appending the pre-trained neural network with a secondary last feed forward layer configured to output a plurality of parameters. The method further includes updating each one of the plurality of parameters by: 1) multiplying each one of the plurality of parameters by a first factor to produce a plurality of resultant parameters; and 2) adding a second term to each one of the plurality of resultant parameters, wherein both the first factor and the second term vary due to backpropagation. The method further includes using a loss function to determine the distance between a known class embedding and an input from an input dataset. Lastly, the method includes updating one or more weights associated with the number of variables in the pre-trained neural network.

Abstract: This application relates to recombinant adeno-associated virus (rAAV) packaging and/or producer cell lines which have been engineered to reduce expression and/or activity of one or more genes and/or proteins to increase rAAV titers. The methods of generating the engineered cell lines have also been described herein.

Abstract: Techniques for session-based device grouping are described. In an example, a computer system receives first data requesting an output, determines a function to provide content data based at least in part on the first data, determines a session identifier of a session associated with execution of the function, and determines session data associated with the session identifier. The session data includes a first device identifier of a first device, an indication that the first device is outputting the content data, and a second device identifier of a second device. The computer system also causes, based at least in part on the session data including the second device identifier, the second device to output the content data.

Abstract: Methods and systems are disclosed for leveraging user premises supplied electric power to power active components in an information delivery network. In response to one or more conditions, an active component may switch an input power path from using grid-supplied or battery power to draw power from a user premises. The decision to switch the power path may be based on a number of conditions, for example, whether power is available from the grid, the relative cost of power from the user premises and whether the power from the user premises includes power from a renewable source.

Abstract: Disclosed are methods and systems for displaying content. In an aspect, a plurality of content items can be displayed on one user device according to user preference. An example method can comprise positioning a first set of pixels associated with a user device so that first content displayed via the first set of pixels can be viewable in a first viewing location. A second set of pixels associated with the user device can be positioned so that second content displayed via the second set of pixels can be viewable in a second viewing location. The second content can be different from the first content.

Abstract: A protective device for electrical conduits including a body having a lower opening for engaging with a first conduit and a central cavity for receiving conductors extending from the first conduit to a second conduit, a top member having an upper opening for engaging with the second conduit, and a coupler slidably engaged around the body, the coupler slidable between an open position distal to the top member and a closed position attached to the top member.

Abstract: A novel maize variety designated X15R410 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X15R410 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X15R410 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X15R410, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X15R410 are provided. Methods for producing maize varieties derived from maize variety X15R410 and methods of using maize variety X15R410 are disclosed.

Abstract: A protective device for electrical conduits including a body having a lower opening for engaging with a first conduit and a central cavity for receiving conductors extending from the first conduit to a second conduit, a top member having an upper opening for engaging with the second conduit, and a coupler extendable between the body and the top member to close the protective device, wherein the coupler includes an exterior wall with at least one orifice configured for receiving a fastener.

Abstract: Techniques for performing speech processing using multi-modal widget information are described. A system may receive input data corresponding to a user input. The system may also receive widget context data corresponding to one or more multi-modal widgets active at a device. The system may use the widget context data to perform natural language understanding (NLU) processing with respect to the user input, and for selecting a skill component for responding to the user input. The system may send a widget identifier to the skill component when invoking the skill to respond to the user input.

Abstract: A novel maize variety designated 1PFWA03 and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety 1PFWA03 with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 1PFWA03 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety 1PFWA03 or a locus conversion of 1PFWA03 with another maize variety.

Abstract: A novel maize variety designated X15R412 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X15R412 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X15R412 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X15R412, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X15R412 are provided. Methods for producing maize varieties derived from maize variety X15R412 and methods of using maize variety X15R412 are disclosed.

Abstract: A device may include a processor configured to obtain a time series of documents; determine query scores for particular documents of the time series of documents based on a set of query terms; and determine time scores for the particular documents based on timestamps associated with the particular documents. The processor may be further configured to compute document relevancy scores for the particular documents based on a combination of the query scores and the time scores for the particular documents; order the particular documents based on the computed relevancy scores; and generate a document summary by applying a document summarizer applied to the ordered particular documents.