Patents by Inventor Nicholas Barker

Nicholas Barker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210228682
    Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.
    Type: Application
    Filed: January 28, 2021
    Publication date: July 29, 2021
    Applicant: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes Carolus Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Patent number: 10940180
    Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: March 9, 2021
    Assignee: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Patent number: 10845351
    Abstract: A method of processing signals comprising: obtaining an electrical signal from one or more plant specimens; and processing said obtained electrical signal to generate plant data; wherein the plant data is data indicative of a characteristic of said one or more plant specimens, wherein said characteristic comprises at least one of: a measure of the health of said one or more plant specimens, a measure of the vitality of said one or more plant specimens, and a reaction to environmental changes of said one or more plant specimens.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: November 24, 2020
    Assignee: Vivent sárl
    Inventors: Nigel Christopher Wallbridge, Carrol Annette Plummer, Martin Timms, Caleb Carroll, Nicholas Barker
  • Publication number: 20200302338
    Abstract: There is provided a method of assessing a characteristic of a plant (2), comprising: obtaining a training dataset, wherein the training dataset comprises first data characterising a first electrical signal obtained from a first plant during a first time period when a stressor is present in the first plant or a growth environment of the first plant, second data characterising a second electrical signal obtained from the first plant during a second time period when a stressor is not present in the first plant or the growth environment of the first plant, and third data indicative of a characteristic of the first plant during the first time period and a characteristic of the first plant during the second time period; training a machine learning model based upon the training dataset; obtaining a third electrical signal from a second plant; and assessing, using the trained machine learning model, a characteristic of the second plant based upon the third electrical signal.
    Type: Application
    Filed: March 17, 2020
    Publication date: September 24, 2020
    Inventors: Caleb Carroll, Nigel Christopher Wallbridge, Nicholas Barker, Laura Raileanu, Fabien Dutoit, Marco Mazzo, Cedric Camps, Daniel Tran, Carrol Annette Plummer
  • Patent number: 10173059
    Abstract: An apparatus comprising: an electrical signal generation device configured to generate a first electrical signal, the first signal being based upon captured or expected data related to one or more human or animal subjects; and an electrical signal application device configured to apply the first electrical signal in a processed or unprocessed form to a human or animal subject.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: January 8, 2019
    Assignee: VIVENT SÁRL
    Inventors: Nigel Christopher Wallbridge, Carrol Annette Plummer, Martin Timms, Caleb Carroll, Nicholas Barker
  • Publication number: 20180267006
    Abstract: A method of processing signals comprising: obtaining an electrical signal from one or more plant specimens; and processing said obtained electrical signal to generate plant data; wherein the plant data is data indicative of a characteristic of said one or more plant specimens, wherein said characteristic comprises at least one of: a measure of the health of said one or more plant specimens, a measure of the vitality of said one or more plant specimens, and a reaction to environmental changes of said one or more plant specimens.
    Type: Application
    Filed: August 22, 2016
    Publication date: September 20, 2018
    Inventors: Nigel Christopher WALLBRIDGE, Carrol Annette PLUMMER, Martin TIMMS, Caleb CARROLL, Nicholas BARKER
  • Patent number: 10071515
    Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold Includes a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold including a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly includes motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly includes a base and a pair of arms extending from the base, wherein each arm includes a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle includes a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: September 11, 2018
    Assignee: Pipeline Induction Heat Ltd.
    Inventors: Michael George, Anthony Dibble, Nicholas Barker
  • Publication number: 20180221441
    Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.
    Type: Application
    Filed: November 15, 2017
    Publication date: August 9, 2018
    Applicant: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Patent number: 9833496
    Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: December 5, 2017
    Assignee: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Publication number: 20170151308
    Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.
    Type: Application
    Filed: September 23, 2014
    Publication date: June 1, 2017
    Applicant: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Publication number: 20160144173
    Abstract: An apparatus comprising: an electrical signal generation device configured to generate a first electrical signal, the first signal being based upon captured or expected data related to one or more human or animal subjects; and an electrical signal application device configured to apply the first electrical signal in a processed or unprocessed form to a human or animal subject.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 26, 2016
    Inventors: Nigel Christopher WALLBRIDGE, Carrol Annette PLUMMER, Martin TIMMS, Caleb CARROLL, Nicholas BARKER
  • Publication number: 20150231201
    Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.
    Type: Application
    Filed: September 23, 2014
    Publication date: August 20, 2015
    Applicant: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Publication number: 20150044320
    Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold comprises a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold comprising a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly comprises motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly comprises a base and a pair of arms extending from the base, wherein each arm comprises a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle comprises: a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.
    Type: Application
    Filed: August 7, 2014
    Publication date: February 12, 2015
    Inventors: Michael George, Anthony Dibble, Nicholas Barker
  • Publication number: 20150042007
    Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold comprises a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold comprising a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly comprises motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly comprises a base and a pair of arms extending from the base, wherein each arm comprises a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle comprises: a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.
    Type: Application
    Filed: August 7, 2014
    Publication date: February 12, 2015
    Inventors: Michael George, Anthony Dibble, Nicholas Barker
  • Patent number: 8906631
    Abstract: Described are the use of stem cell markers for the isolation of stem cells and the use of the obtained stem cells in, for example, research or treatment, such as for the preparation of a medicament for the treatment of damaged or diseased tissue. In one aspect, provided is a method for obtaining or isolating stem cells that comprises preparing a cell suspension from a tissue or organ sample, contacting the cell suspension with an Lgr 6 or 5 binding compound, identifying the cells bound to the binding compound, and isolating the stem cells from the binding compound. Further described are methods and compositions for cancer treatment, for example, by eradicating cancer stem cells.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: December 9, 2014
    Assignee: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Johannes Carolus Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
  • Publication number: 20140330694
    Abstract: Methods and a system for preparing a financial transaction are described. Input data for a financial information query is received. A query is performed and data for a number of information panels is returned. The data relates to trading information for at least one tradable object associated with the input data. A user may select one or more information panels to generate a trade prompt, which is communicable to a user of a second computing device. Access to the trade prompt allows the user of the second computing device to instruct a trade of one or more tradable objects from the second computing device.
    Type: Application
    Filed: May 3, 2013
    Publication date: November 6, 2014
    Applicant: The Royal Bank of Scotland Group PLC
    Inventors: Nicholas Barker, Craig Goulding
  • Publication number: 20140163048
    Abstract: This disclosure describes solid forms of the compound of Formula (I) and pharmaceutical compositions for inhibiting the TRPA1 ion channel and/or medical conditions related to TRPA1, such as pain.
    Type: Application
    Filed: August 9, 2013
    Publication date: June 12, 2014
    Applicant: Cubist Pharmaceuticals, Inc.
    Inventors: Nicholas Barker, Jian-Qiao Gu, Gaauri NAIK, Jan-Ji LAI, Stephen MACHATHA, You Seok Hwang, Pradip M. Pathare
  • Patent number: 8737048
    Abstract: Patient monitoring systems can include a display unit and a patient parameter module. The patient parameter module can be connected to a docking region so as to communicate with the display unit in two or more orientations.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: May 27, 2014
    Assignee: Mindray DS USA, Inc.
    Inventors: James Fidacaro, James Patrick Thrower, Geoffrey C. Jawidzik, Nicholas Barker, Allan Cameron, Jim Wilson, Hilary Farnsworth, David Chastain
  • Publication number: 20140031637
    Abstract: Patient monitoring systems can include a display unit and a patient parameter module. The patient parameter module can be connected to a docking region so as to communicate with the display unit in two or more orientations.
    Type: Application
    Filed: August 29, 2012
    Publication date: January 30, 2014
    Applicant: Mindray DS USA, Inc.
    Inventors: James Fidacaro, James Patrick Thrower, Geoffrey C. Jawidzik, Nicholas Barker, Allan Cameron, Jim Wilson, Hilary Farnsworth, David Chastain
  • Patent number: 8279586
    Abstract: Patient monitoring systems can include a display unit and a patient parameter module. The patient parameter module can be connected to a docking region so as to communicate with the display unit in two or more orientations.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: October 2, 2012
    Assignee: Mindray DS USA, Inc.
    Inventors: James Fidacaro, James Patrick Thrower, Geoffrey C. Jawidzik, Nicholas Barker, Allan Cameron, Jim Wilson, Hilary Farnsworth, David Chastain