Patents by Inventor Nicholas Barker
Nicholas Barker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11426908Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold comprises a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold comprising a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly comprises motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly comprises a base and a pair of arms extending from the base, wherein each arm comprises a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle comprises: a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.Type: GrantFiled: August 7, 2014Date of Patent: August 30, 2022Assignee: Pipeline Induction Heat Ltd.Inventors: Michael George, Anthony Dibble, Nicholas Barker
-
Publication number: 20210228682Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.Type: ApplicationFiled: January 28, 2021Publication date: July 29, 2021Applicant: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes Carolus Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Patent number: 10940180Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.Type: GrantFiled: November 15, 2017Date of Patent: March 9, 2021Assignee: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Patent number: 10845351Abstract: A method of processing signals comprising: obtaining an electrical signal from one or more plant specimens; and processing said obtained electrical signal to generate plant data; wherein the plant data is data indicative of a characteristic of said one or more plant specimens, wherein said characteristic comprises at least one of: a measure of the health of said one or more plant specimens, a measure of the vitality of said one or more plant specimens, and a reaction to environmental changes of said one or more plant specimens.Type: GrantFiled: August 22, 2016Date of Patent: November 24, 2020Assignee: Vivent sárlInventors: Nigel Christopher Wallbridge, Carrol Annette Plummer, Martin Timms, Caleb Carroll, Nicholas Barker
-
Publication number: 20200302338Abstract: There is provided a method of assessing a characteristic of a plant (2), comprising: obtaining a training dataset, wherein the training dataset comprises first data characterising a first electrical signal obtained from a first plant during a first time period when a stressor is present in the first plant or a growth environment of the first plant, second data characterising a second electrical signal obtained from the first plant during a second time period when a stressor is not present in the first plant or the growth environment of the first plant, and third data indicative of a characteristic of the first plant during the first time period and a characteristic of the first plant during the second time period; training a machine learning model based upon the training dataset; obtaining a third electrical signal from a second plant; and assessing, using the trained machine learning model, a characteristic of the second plant based upon the third electrical signal.Type: ApplicationFiled: March 17, 2020Publication date: September 24, 2020Inventors: Caleb Carroll, Nigel Christopher Wallbridge, Nicholas Barker, Laura Raileanu, Fabien Dutoit, Marco Mazzo, Cedric Camps, Daniel Tran, Carrol Annette Plummer
-
Patent number: 10173059Abstract: An apparatus comprising: an electrical signal generation device configured to generate a first electrical signal, the first signal being based upon captured or expected data related to one or more human or animal subjects; and an electrical signal application device configured to apply the first electrical signal in a processed or unprocessed form to a human or animal subject.Type: GrantFiled: June 13, 2014Date of Patent: January 8, 2019Assignee: VIVENT SÁRLInventors: Nigel Christopher Wallbridge, Carrol Annette Plummer, Martin Timms, Caleb Carroll, Nicholas Barker
-
Publication number: 20180267006Abstract: A method of processing signals comprising: obtaining an electrical signal from one or more plant specimens; and processing said obtained electrical signal to generate plant data; wherein the plant data is data indicative of a characteristic of said one or more plant specimens, wherein said characteristic comprises at least one of: a measure of the health of said one or more plant specimens, a measure of the vitality of said one or more plant specimens, and a reaction to environmental changes of said one or more plant specimens.Type: ApplicationFiled: August 22, 2016Publication date: September 20, 2018Inventors: Nigel Christopher WALLBRIDGE, Carrol Annette PLUMMER, Martin TIMMS, Caleb CARROLL, Nicholas BARKER
-
Patent number: 10071515Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold Includes a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold including a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly includes motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly includes a base and a pair of arms extending from the base, wherein each arm includes a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle includes a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.Type: GrantFiled: August 7, 2014Date of Patent: September 11, 2018Assignee: Pipeline Induction Heat Ltd.Inventors: Michael George, Anthony Dibble, Nicholas Barker
-
Publication number: 20180221441Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.Type: ApplicationFiled: November 15, 2017Publication date: August 9, 2018Applicant: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Patent number: 9833496Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.Type: GrantFiled: September 23, 2014Date of Patent: December 5, 2017Assignee: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Publication number: 20170151308Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.Type: ApplicationFiled: September 23, 2014Publication date: June 1, 2017Applicant: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Publication number: 20160144173Abstract: An apparatus comprising: an electrical signal generation device configured to generate a first electrical signal, the first signal being based upon captured or expected data related to one or more human or animal subjects; and an electrical signal application device configured to apply the first electrical signal in a processed or unprocessed form to a human or animal subject.Type: ApplicationFiled: June 13, 2014Publication date: May 26, 2016Inventors: Nigel Christopher WALLBRIDGE, Carrol Annette PLUMMER, Martin TIMMS, Caleb CARROLL, Nicholas BARKER
-
Publication number: 20150231201Abstract: The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention further relates to the obtained stem cells and their use in for example research or treatment, for example, for the preparation of a medicament for the treatment of damaged or diseased tissue. In one of the embodiments, the invention provides a method for obtaining (or isolating) stem cells comprising optionally preparing a cell suspension from a tissue or organ sample, contacting said cell suspension with an Lgr 6 or 5 binding compound, identify the cells bound to said binding compound, and optionally isolating the stem cells from said binding compound. The invention further relates to means suitable for cancer treatment and even more specific for the treatment of cancer by eradicating cancer stem cells.Type: ApplicationFiled: September 23, 2014Publication date: August 20, 2015Applicant: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes C. Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Publication number: 20150044320Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold comprises a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold comprising a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly comprises motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly comprises a base and a pair of arms extending from the base, wherein each arm comprises a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle comprises: a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.Type: ApplicationFiled: August 7, 2014Publication date: February 12, 2015Inventors: Michael George, Anthony Dibble, Nicholas Barker
-
Publication number: 20150042007Abstract: A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold comprises a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold comprising a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly comprises motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly comprises a base and a pair of arms extending from the base, wherein each arm comprises a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle comprises: a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.Type: ApplicationFiled: August 7, 2014Publication date: February 12, 2015Inventors: Michael George, Anthony Dibble, Nicholas Barker
-
Patent number: 8906631Abstract: Described are the use of stem cell markers for the isolation of stem cells and the use of the obtained stem cells in, for example, research or treatment, such as for the preparation of a medicament for the treatment of damaged or diseased tissue. In one aspect, provided is a method for obtaining or isolating stem cells that comprises preparing a cell suspension from a tissue or organ sample, contacting the cell suspension with an Lgr 6 or 5 binding compound, identifying the cells bound to the binding compound, and isolating the stem cells from the binding compound. Further described are methods and compositions for cancer treatment, for example, by eradicating cancer stem cells.Type: GrantFiled: May 10, 2010Date of Patent: December 9, 2014Assignee: Koninklijke Nederlandse Akademie van WetenschappenInventors: Johannes Carolus Clevers, Nicholas Barker, Andrea Haegebarth, Marcus Lambertus Van de Wetering
-
Publication number: 20140330694Abstract: Methods and a system for preparing a financial transaction are described. Input data for a financial information query is received. A query is performed and data for a number of information panels is returned. The data relates to trading information for at least one tradable object associated with the input data. A user may select one or more information panels to generate a trade prompt, which is communicable to a user of a second computing device. Access to the trade prompt allows the user of the second computing device to instruct a trade of one or more tradable objects from the second computing device.Type: ApplicationFiled: May 3, 2013Publication date: November 6, 2014Applicant: The Royal Bank of Scotland Group PLCInventors: Nicholas Barker, Craig Goulding
-
Publication number: 20140163048Abstract: This disclosure describes solid forms of the compound of Formula (I) and pharmaceutical compositions for inhibiting the TRPA1 ion channel and/or medical conditions related to TRPA1, such as pain.Type: ApplicationFiled: August 9, 2013Publication date: June 12, 2014Applicant: Cubist Pharmaceuticals, Inc.Inventors: Nicholas Barker, Jian-Qiao Gu, Gaauri NAIK, Jan-Ji LAI, Stephen MACHATHA, You Seok Hwang, Pradip M. Pathare
-
Patent number: 8737048Abstract: Patient monitoring systems can include a display unit and a patient parameter module. The patient parameter module can be connected to a docking region so as to communicate with the display unit in two or more orientations.Type: GrantFiled: August 29, 2012Date of Patent: May 27, 2014Assignee: Mindray DS USA, Inc.Inventors: James Fidacaro, James Patrick Thrower, Geoffrey C. Jawidzik, Nicholas Barker, Allan Cameron, Jim Wilson, Hilary Farnsworth, David Chastain
-
Publication number: 20140031637Abstract: Patient monitoring systems can include a display unit and a patient parameter module. The patient parameter module can be connected to a docking region so as to communicate with the display unit in two or more orientations.Type: ApplicationFiled: August 29, 2012Publication date: January 30, 2014Applicant: Mindray DS USA, Inc.Inventors: James Fidacaro, James Patrick Thrower, Geoffrey C. Jawidzik, Nicholas Barker, Allan Cameron, Jim Wilson, Hilary Farnsworth, David Chastain