Abstract: The present application provides a method of producing a “liquid” array of ligand (such as glycan) modified bacteriophage where the ligand modification is encoded genetically within the bacteriophage genome. This method will allow for the determination of the ligand binding profile of biomacromolecules and cells. Furthermore the method allows the elucidation of ligand-protein interactions where ligand binding is co-operative and synergistic.

Abstract: A technique for using symbol position patterns includes performing a selection operation, using the random number generator and a data structure comprising a plurality of symbol position patterns to obtain one of the symbol position patterns, and modifying display of the plurality of symbol positions in accordance with the selected symbol position pattern. A symbol selection instance is performed using a lookup table comprising a plurality of reel strips, wherein the reel strips include a designated symbol with respect to the plurality of symbol positions until an end condition is met, and upon all the symbol positions of the selected symbol position pattern being occupied by the designated symbol when the end condition is met, an outcome is determined.

Abstract: A technique for using symbol position patterns includes performing a selection operation, using the random number generator and a data structure comprising a plurality of symbol position patterns to obtain one of the symbol position patterns, and modifying display of the plurality of symbol positions in accordance with the selected symbol position pattern. A symbol selection instance is performed using a lookup table comprising a plurality of reel strips, wherein the reel strips include a designated symbol with respect to the plurality of symbol positions until an end condition is met, and upon all the symbol positions of the selected symbol position pattern being occupied by the designated symbol when the end condition is met, an outcome is determined.

Abstract: A controlled motion hinge assembly having a base with a first actuator mount, a pivot arm with a second actuator mount, a hinge pivotally connecting the base to the pivot arm to be movable between an extended position and a retracted position, and an actuator shaft. The shaft has a first end, a second end, and a threaded body extending between the first and second ends. The first end is configured to receive a drive torque about the actuator shaft axis. The second end is rotatably connected to the second actuator mount, but fixed thereto along the actuator shaft axis. The threaded body engages a threaded bore of the first actuator mount such that rotation of the body causes the first actuator mount to move along the actuator shaft axis. Also provided is a pole assembly, and a method for retrofitting a pole, with a controlled motion hinge.

Abstract: A gaming system implements a method of gaming. The gaming system includes one or more gaming devices configured to enable a player to place a wager for play of a wagering game, and each gaming device includes a player tracking/marketing module (PTM). A plurality of avatars are selectable by a player, and after receiving inputs from the player relating to the avatars selected and credit allocation for each selected avatar, one is designated as the active avatar. The system receives a credit wager to initiate play of a wagering game, and in response to a user input triggering game play via the gaming device, the PTM records credit wagered for game play against the active avatar. In response to a winning outcome for the triggered game play, the PTM records any award for the game outcome against one or more avatars in accordance with allocation criteria.

Abstract: A gaming system implements a method of gaming. The gaming system includes one or more gaming devices configured to enable a player to place a wager for play of a wagering game, and each gaming device includes a player tracking/marketing module (PTM). A plurality of avatars are selectable by a player, and after receiving one or more inputs from the player relating to the avatars selected and credit allocation for each selected avatar, one is designated as the active avatar for game play. The system receives, via a credit input mechanism, a credit wager to initiate play of a wagering game, and in response to a user input triggering game play via the gaming device, the PTM records credit wagered for game play against the active avatar. Moreover, in response to a winning outcome occurring in a game outcome for the triggered game play, the PTM records any award for the game outcome against one or more avatars in accordance with allocation criteria.

Abstract: A technique for using symbol position patterns includes performing a selection operation, using the random number generator and a data structure comprising a plurality of symbol position patterns to obtain one of the symbol position patterns, and modifying display of the plurality of symbol positions in accordance with the selected symbol position pattern. A symbol selection instance is performed using a lookup table comprising a plurality of reel strips, wherein the reel strips include a designated symbol with respect to the plurality of symbol positions until an end condition is met, and upon all the symbol positions of the selected symbol position pattern being occupied by the designated symbol when the end condition is met, an outcome is determined.

Abstract: A controlled motion hinge assembly having a base with a first actuator mount, a pivot arm with a second actuator mount, a hinge pivotally connecting the base to the pivot arm to be movable between an extended position and a retracted position, and an actuator shaft. The shaft has a first end, a second end, and a threaded body extending between the first and second ends. The first end is configured to receive a drive torque about the actuator shaft axis. The second end is rotatably connected to the second actuator mount, but fixed thereto along the actuator shaft axis. The threaded body engages a threaded bore of the first actuator mount such that rotation of the body causes the first actuator mount to move along the actuator shaft axis. Also provided is a pole assembly, and a method for retrofitting a pole, with a controlled motion hinge.

Abstract: Innovations in implementing a skill-based interaction mechanism after random number generator (“RNG”)-based outcome determination in an electronic gaming device are described herein. For example, after RNG-based outcome determination, objects may be displayed on a touchscreen display of the electronic gaming device. A given object may be associated with one or more functions to be carried out upon interaction with the object (e.g., selection of the object by the user on the touchscreen display). For example, upon selection of the object, a function associated with the object is carried out to change display of the object or generate an additional outcome using the RNG.

Abstract: This invention related to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by the CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular, the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein.

Abstract: An electronic latch assembly includes a latch bolt movable between an extended position and a retracted position; and a motor having a rotatable output shaft arrangement that is either directly or indirectly connected to the latch bolt for moving the latch bolt between the extended and retracted positions and rotating the output shaft arrangement between a first angular position in which the latch bolt is capable of being translated to the retracted position and a second angular position in which the latch bolt is locked and not capable of being translated to the retracted position.

Abstract: A gaming system implements a method of gaming. The gaming system includes one or more gaming devices configured to enable a player to place a wager for play of a wagering game, and each gaming device includes a player tracking/marketing module (PTM). A plurality of avatars are selectable by a player, and after receiving one or more inputs from the player relating to the avatars selected and credit allocation for each selected avatar, one is designated as the active avatar for game play. The system receives, via a credit input mechanism, a credit wager to initiate play of a wagering game, and in response to a user input triggering game play via the gaming device, the PTM records credit wagered for game play against the active avatar. Moreover, in response to a winning outcome occurring in a game outcome for the triggered game play, the PTM records any award for the game outcome against one or more avatars in accordance with allocation criteria.

Abstract: An electronic latch assembly includes a latch bolt movable between an extended position and a retracted position; and a motor having a rotatable output shaft arrangement that is either directly or indirectly connected to the latch bolt for moving the latch bolt between the extended and retracted positions and rotating the output shaft arrangement between a first angular position in which the latch bolt is capable of being translated to the retracted position and a second angular position in which the latch bolt is locked and not capable of being translated to the retracted position.

Abstract: A gaming system implements a method of gaming. The gaming system includes one or more gaming devices configured to enable a player to place a wager for play of a wagering game, and each gaming device includes a player tracking/marketing module (PTM). A plurality of avatars are selectable by a player, and after receiving one or more inputs from the player relating to the avatars selected and credit allocation for each selected avatar, one is designated as the active avatar for game play. The system receives, via a credit input mechanism, a credit wager to initiate play of a wagering game, and in response to a user input triggering game play via the gaming device, the PTM records credit wagered for game play against the active avatar. Moreover, in response to a winning outcome occurring in a game outcome for the triggered game play, the PTM records any award for the game outcome against one or more avatars in accordance with allocation criteria.

Abstract: This invention related to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by the CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular, the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein.

Abstract: A gaming system implements a method of gaming. The gaming system includes one or more gaming devices configured to enable a player to place a wager for play of a wagering game, and each gaming device includes a player tracking/marketing module (PTM). A plurality of avatars are selectable by a player, and after receiving one or more inputs from the player relating to the avatars selected and credit allocation for each selected avatar, one is designated as the active avatar for game play. The system receives, via a credit input mechanism, a credit wager to initiate play of a wagering game, and in response to a user input triggering game play via the gaming device, the PTM records credit wagered for game play against the active avatar. Moreover, in response to a winning outcome occurring in a game outcome for the triggered game play, the PTM records any award for the game outcome against one or more avatars in accordance with allocation criteria.

Abstract: A gaming system implements a method of gaming. The gaming system includes one or more gaming devices configured to enable a player to place a wager for play of a wagering game, and each gaming device includes a player tracking/marketing module (PTM). A plurality of avatars are selectable by a player, and after receiving one or more inputs from the player relating to the avatars selected and credit allocation for each selected avatar, one is designated as the active avatar for game play. The system receives, via a credit input mechanism, a credit wager to initiate play of a wagering game, and in response to a user input triggering game play via the gaming device, the PTM records credit wagered for game play against the active avatar. Moreover, in response to a winning outcome occurring in a game outcome for the triggered game play, the PTM records any award for the game outcome against one or more avatars in accordance with allocation criteria.

Abstract: The present application provides a method of producing a “liquid” array of ligand (such as glycan) modified bacteriophage where the ligand modification is encoded genetically within the bacteriophage genome. This method will allow for the determination of the ligand binding profile of biomacromolecules and cells. Furthermore the method allows the elucidation of ligand-protein interactions where ligand binding is co-operative and synergistic.

Abstract: A gaming machine comprises a reel strip comprising a plurality of trigger symbols, stack symbols, wild symbols and standard symbols, a symbol selector for selecting a plurality of symbols from the reel strip to be displayed on a display during play of a base game, wherein in the base game, said wild symbols substitute for only stack symbols and standard symbols, an outcome evaluator for monitoring play of the game, wherein when a predefined number of trigger symbols is selected for display, a plurality of feature games are triggered, and an interface for receiving a selection of one of the plurality of triggered feature games to play.